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1973

South Dakota State University

Virology

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Application Of 125i To The Detection And Assay Of Viruses And Viral Antibody Adsorbed To Latex Particles, Charles Steven Duvall Jan 1973

Application Of 125i To The Detection And Assay Of Viruses And Viral Antibody Adsorbed To Latex Particles, Charles Steven Duvall

Electronic Theses and Dissertations

This study, then, was undertaken to develop a universal, in vitro, extracellular method utilizing fluorescence and radioactive 125I to rapidly detect, identify, and quantitate pathogenic viruses and viral antibodies. Focus of the study is the CLAM model, which consists of inert latex particles, plus four radioactively labeled components: antibody, virus, enzyme (RNase) and fluorochrome (FITC).