Life Sciences Commons^™

Effects Of Home-Based High-Intensity Interval Training Versus Continuous Walking On Cognition In Overweight And Obese Women, Kelsey C. Bourbeau

Health, Exercise, and Sports Sciences ETDs

Objective: The purpose of the present study was to determine whether six weeks of home-based high-intensity interval training versus six weeks of moderate-intensity walking improves cognition, depression, and anxiety in women that are overweight or obese. Design: A randomized control trial design. Subjects: Twelve sedentary women characterized as overweight or obese were randomized into either a six-week home-based high-intensity interval training (HIIT, n = 6, 26.6 ± 8.9 years, 37.4 ± 4.9% body fat) group or a six-week moderate-intensity walking (Walk, n = 6, 22.5 ± 3.7 years, 40.2 ± 4.1% body fat) group. Main Measures: Pre- and post-intervention, participants …

Temporal Effects Of Acute Moderate Intensity Physical Activity On Working Memory Performance In Young Adults, Kimberly Loy Seibold

Graduate Theses and Dissertations

An ample amount of research suggests that increases in physical activity in young adults could help improve memory and cognitive functions which may aid in academic success (Johnson & Loprinzi, 2019; Perini et al., 2016). A sufficient working memory is critical to learning because it allows us to temporarily store and compare multiple informational items at one time to form a new concept or solve a problem (Cowan, 2013). The purpose of this study was to examine the temporal effects of acute moderate intensity physical activity on working memory in young adults. This study utilized a within-groups (repeated measures) cross-over …

Metabolic Foundations Of Exercise-Induced Cardiac Growth., Kyle Fulghum

Electronic Theses and Dissertations

Regular aerobic exercise promotes physiological cardiac growth, which is an adaptive response thought to enable the heart to meet higher physical demands. Cardiac growth involves coordination of catabolic and anabolic activities to support ATP generation, macromolecule biosynthesis, and myocyte hypertrophy. Although previous studies suggest that exercise-induced reductions in cardiac glycolysis are critical for physiological myocyte hypertrophy, it remains unclear how exercise influences the many interlinked pathways of metabolism that support adaptive remodeling of the heart. In this thesis project, we tested the general hypothesis that aerobic exercise promotes physiological cardiac growth by coordinating myocardial metabolism to promote glucose-supported anabolic pathway …

Non-Photic Mechanisms Of Entrainment In Bmal1 Deficient Conditions, Jamie Tran

Dissertations & Theses (Open Access)

Maintaining our internal circadian (i.e. 24 -hour) clock is imperative to our daily biological and mental well-being. Large epidemiological studies have shown that disruptions of our circadian rhythms can lead to poor mental health, metabolic diseases, and various types of cancer. Various external cues that have become a part of the modern times such as electricity, shift -work, rapid travel across various time zones, easier access to nutritionally unbalanced food items, and various rigid social demands have deleterious effects on our internal clock, and generally reduce robustness of the circadian clock. The two following projects aim to examine two fundamental …

Early-Exercise Effects On Mice Tendon Remodeling, Miles Valencia

Electronic Theses, Projects, and Dissertations

Tendons connect and transmit energy between muscles and bones and play a key role in movement. Tendon remodels by breaking down and absorbing tendon components including collagen fibers and elastin while replacing them with newly formed tendon. These processes can be influenced by short- and long-term factors such as exercise and aging; the magnitude of influence on tendon remodeling remains unclear. I researched the effects of maturation and exercise on tendon remodeling using a mice colony artificially selected for high voluntary wheel running called high-runner mice. Control and high-runner linetype mice were separated into 2 age cohorts that started training …

From Young To Old: The Effects Of Sedentary-Aging And Exercise Interventions On Structural Plasticity Of Lumbar Motor Neurons, Nmj, And Glial Cell Line-Derived Neurotrophic Factor Expression, Alberto Felipe Cintron-Colon

Dissertations

Neuromuscular weakness has been associated with age progression. A possible reason is a disconnection between muscle and neuron, causing components from both the central and peripheral nervous systems to deteriorate. Exercise, however, has beneficial effects for both muscle and nervous tissue, inducing neuroprotection. Neurotrophic factors are powerful regulators of neuronal maintenance and synaptic strength. Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor that has been shown to be a potent survival factor for somatic motor neurons that innervate skeletal muscle.

This study aims to evaluate changes in structural plasticity of motor neurons in the lumbar spinal cord and …

Effects Of Exercise On Fear Behavior In Zebrafish, Tyler Kuni

Undergraduate Theses and Capstone Projects

The experiment focuses on the behaviors of zebrafish when they are exposed to an environment that causes anxiety or fear behavior and how controlled amounts of exercise will affect the behaviors of the fish. Fearful behavior was measured by the activity level and area of the swimming during the fear conditioning process. We investigated whether the changes in activity level, areas of swimming in the tank, and depth of swimming in the tank were significant as well as if there was an interaction effect between the fear conditioning and our dependent variables. Zebrafish were randomly assigned to three groups: the …

The Effects Of Wearing A Sports Mask Compared To A Standard Surgical Face Mask During The Forestry 5 Minute Submaximal Step Test, Christian Kumar

Undergraduate Theses and Capstone Projects

The existence of the COVID-19 global pandemic has forced the introduction of wearing face masks when in public spaces or in near proximity to others. Therefore, the purpose of this study was to determine the physiological effects and perceptions of wearing a sports mask compared to a standard surgical face mask during exercise. Nineteen subjects, 10 male and 9 female subjects ranging between 19-25 years of age completed the 5-minute Forestry Step Test randomized to wear either an Under Armour sports mask, a standard surgical mask, or wearing no mask. Resting and post-exercise heart rate, RPE, and metabolic data was …

The Effects Of Acute Exercise Intensity On Retrieval-Induced Forgetting, Geoffrey Reliquias

Honors Theses

Previous research has indicated that aspects of cognitive inhibition may be enhanced after engaging in acute exercise. Notably, cognitive inhibition has been theorized as a potential mechanism for a form of active forgetting known as retrieval-induced forgetting (RIF). Given that cognitive inhibition may explain the RIF phenomenon, and is also influenced by exercise, it is plausible that acute exercise may directly influence RIF. To our knowledge, only one study has examined whether acute exercise has an effect on RIF. The findings of that study did not find a statistically significant effect for RIF; however, we believe that the rather small …

Effects Of A Remote Exercise Intervention On Aerobic Endurance In Individuals With Down Syndrome, Andrew Murata, Elena Wolf, Jonathan Crimm, Benjamin Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: Down syndrome (Ds) or Trisomy 21 is a common genetic birth condition, and those with Ds typically display decreased cardiorespiratory fitness compared to those without Ds, potentially leading to an increased risk for cardiovascular conditions and mortality. Low cardiorespiratory fitness is partially caused by low physical activity levels in this population. The COVID-19 pandemic caused community-based activity programs to shut down, as individuals with Ds are at increased risk for COVID-19 hospitalization and death. Thus, it was vital to explore alternatives of in-person exercise during the pandemic. The purpose of this study was to investigate the effects of a …

Self-Rated Function And Delayed Onset Muscle Soreness (Doms) Responses To 6-Week Supplementation With Waters With Anti-Inflammatory Capabilities (Wac), Kristin Garner

Health, Human Performance and Recreation Undergraduate Honors Theses

Introduction: Researchers have examined the effects of sedentary lifestyles on diminished health outcomes and are pleading individuals to take on a more active lifestyle to prevent these. However, initial efforts to exercise are often dampened by delayed onset muscle soreness (DOMS) and muscle fatigue. This can greatly reduce exercise adherence, making it difficult for individuals to overcome this temporary discomfort. Background: Research has extensively evaluated nonsteroidal anti-inflammatory drugs (NSAIDs) and fruits as anti-inflammatory supplementation to treat DOMS. Berry-derived essences are more highly concentrated in anti-inflammatory substances than regular fruit juices, but there is minimal research on their effects on exercise …

Comparing Various Physiological System Adaptations Following 8 Weeks Of Resistance Training With Or Without Bfr In Older Males, Ricardo Parra

Theses and Dissertations

PURPOSE: The purpose of this study was to compare the effects of 8 weeks of resistance exercise training with and without BFR on: 1), arterial elasticity and hemodynamics (e.g., blood pressure and resting heart rate), 2) muscular force production (e.g., maximal voluntary contraction, force production, electromyography, and estimated one-repetition maximum) in males between the 50 to 70 years of age.

RESULTS: Significant condition difference for reflection magnitude occurred in BFR group (p < 0.05). Significant time*condition effect occurred in Leg Press 1RM, Leg Extension 1RM, Leg Curl 1RM, Chest Press 1RM, and Shoulder Press 1RM (p < 0.05). Significant condition* time interaction occurred for Isokinetic Leg Extension Test (60°/s) (p < 0.05). A significant time*condition interaction occurred during Maximal Voluntary Contraction (MVC) – Root Mean Square for both vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred in the BFR group for the amplitude mean of the MVC in the vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred for median frequency of the MVC (p < 0.05). A significant difference in Estimated Visceral Adipose Tissue occurred in the BFR group (p < 0.05). A significant condition*time interaction occurred in arm fat percentage (p < 0.05). The BFR group had significantly less fat tissue (%) in the left arm (p < 0.01) and in the right arm (p = 0.04). A significant time*main effect occurred in the total lean tissue for the left side of the body (p = 0.04).

CONCLUSION: Using BFR resistance training at a low intensity can achieve similar adaptations seen at high intensities while reducing the risk of injury that comes with heavier loads.

The Effects Of A Telehealth Exercise Intervention On Balance In Adults With Down Syndrome, Mark Barton, Kristina Guerrero, Andrew Martinez, Alexandria Umagat

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: People with Down syndrome (Ds) often present with balance deficits, which compromise their safety during daily activity. While evidence shows that exercise can improve balance in the Ds population, it is unclear if a telehealth method will elicit similar benefits. We aimed to examine the effects of a virtual exercise program on balance in adults with Ds.

Methods: Twenty participants completed a 12-week telehealth exercise program based on the Mann Method. Balance testing took place before and after the intervention, which included: Timed Up and Go (TUG), Modified Clinical Test of Sensory Interaction in Balance (MCTSIB), Frailty and Injuries: …

Effects Of Acute Exercise Intensity On Memory: Considerations Of Timing And Aerobic Endurance, William Meyers, Caroline Loeb, Mary Collins West, Bailey Bass

Honors Theses

The primary objective of this study was to find the optimal acute exercise intensity and post-exercise recovery time to enhance memory retention. A secondary objective of study was to evaluate the influence of aerobic endurance on memory and whether endurance capacity interacts with exercise intensity and post-exercise recovery period to influence memory performance. Participants were 54 undergraduate and graduate students at the University of Mississippi, with an age range of 18-23 years. Participants completed 13 visits in total. The first visit evaluated their aerobic endurance, with the remaining 12 visits including a 3 (Intensity: Control, Moderate, Vigorous) by 4 (Post-Exercise …

Molecular Architecture Of Cardiometabolic Responses To Regular Exercise, Jacob L. Barber

Theses and Dissertations

Background: To investigate the molecular mechanisms, determinants, and predictors of cardiometabolic responses to regular exercise, this dissertation had two primary aims: 1) Examine the molecular architecture of cardiometabolic responses to exercise training (unsupervised approach) and 2) Identify molecular signatures of responsiveness to regular exercise within clinically relevant lipoprotein traits (supervised approach).

Methodology: Multi-omics data (17,945 muscle transcripts, 4,979 proteins, 411 metabolites) from participants (n=647) who completed 20 weeks of endurance training as part of the HERITAGE Family Study was collected before and after training. We employed an unsupervised machine learning approach (Aim 1) to identify patterns of molecular responses to …

The Effects Of Exercise Training On Cholesterol Efflux Capacity In The Heritage Family Study, Joshua Adam Hawkins

Theses and Dissertations

Cholesterol efflux capacity (CEC) has been associated with cardiovascular disease risk independent of HDL-C levels. However, the effect of regular exercise on CEC is not yet fully understood. Therefore, we examined the effects of exercise training on CEC in the HERITAGE Family Study. In HERITAGE, subjects participated in an endurance training program that consisted of exercise on a cycle ergometer three times per week for 20 weeks. Global and non-ABCA1 CEC were measured at baseline and post-training in 542 subjects via a cell- based radiolabeled CEC assay. Neither global nor non-ABCA1 CEC significantly changed with training in the whole cohort. …

Examining The Effects Of Exercise-Induced, Physical Stress Overtraining On Stress Biomarkers In Adolescent, C57bl/6 Mice, Curtis Scotty Davis

Theses, Dissertations and Capstones

Exercise has long been established as a therapeutic modality to improve health and related physical fitness, sports performance, and injury/risk reduction in both adults and adolescents (Haff & Triplett, 2015; Kaminsky, 2010). Nonetheless, there is a lack of research investigating the negative effects of exercise overstress (i.e., overtraining syndrome) in these populations, particularly adolescents (Brenner & American Academy of Pediatrics Council on Sports Medicine and Fitness, 2007; Matos & Winsley, 2007). The objective of this study was to examine hormone biochemical markers, anthropometric markers, and behavioral traits, which are associated with overtraining syndrome, in adolescent C57BL/6 mice. A total of …

Changes In Physical Activity And Relationships To Submaximal Exercise Capacity And Cardiac Function During Breast Cancer Therapy, Moriah P. Bellissimo

Theses and Dissertations

Background: Breast cancer (BC) survivors are at high risk for heart failure due to curative cancer therapies. In non-cancer populations, physical activity is a first line treatment for preventing cardiovascular disease. This study examined whether more physical activity was associated with better submaximal exercise capacity and cardiac function during the first three months of cancer therapy.

Methods: Participants included 223 women with stage I-III BC before therapy and after three months of undergoing treatment and 126 controls. Leisure time physical activity was reported using the Godin Sheppard leisure time exercise questionnaire. Cardiac function was assessed by cardiac magnetic resonance, and …