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Full-Text Articles in Life Sciences

The Analysis And Characterisation Of Rotavirus And Norovirus Circulating In The South Of Ireland, Norma Reidy Jan 2006

The Analysis And Characterisation Of Rotavirus And Norovirus Circulating In The South Of Ireland, Norma Reidy

Theses

On average more than 3,000 cases of rotavirus diarrhea are detected annually amongst Irish children less than 3 years of age. Rotavirus disease occurs mainly during the winter months, with peak infections detected from February to April. The symptoms of disease are diarrhea and dehydration, with 80% of patients requiring hospitalisation, The mean duration of hospitalisation is 3-4 days, with an average cost per day of €409. Eighteen percent of infections were detected in infants less than 6 months of age, suggesting inadequate maternal derived protection from existing strains, or the existence of novel strains in Ireland with little or …


Quantification Of Mrna Expression Of Her2/Neu, Estrogen Receptors Eralpha And Erbeta, And Progesterone Receptor Using Real-Time Reverse Transcription Pcr In Small Tumor Biopsies, In Human Breast Cancer, Evonne Marie. Mc Cabe Jan 2006

Quantification Of Mrna Expression Of Her2/Neu, Estrogen Receptors Eralpha And Erbeta, And Progesterone Receptor Using Real-Time Reverse Transcription Pcr In Small Tumor Biopsies, In Human Breast Cancer, Evonne Marie. Mc Cabe

Theses

Early detection is an effective means of reducing cancer mortality. Early detection greatly improves treatment options and the chances for successful treatment. The prognosis for patients with breast cancer is determined by well-established biological features associated with biological aggressiveness, histological grade, tumour size, and nodal involvement. Breast cancer results from multiple genetic abnormalities, and cellular differentiation, tumour growth, and metastatic potential are the end result of these changes. Identification of molecular changes is of considerable value in enhancing the accuracy of prognostic indices, and more importantly, it may indicate various changes as putative targets for therapy. In recent years a …


Molecular Epidemiology Of Antibiotic Resistant Salmonella Enterica Strains From Different Animal And Human Sources In Ireland, David George Lee Jan 2006

Molecular Epidemiology Of Antibiotic Resistant Salmonella Enterica Strains From Different Animal And Human Sources In Ireland, David George Lee

Theses

In this study, 176 isolates of Salmonella were collected from different laboratories in Ireland. All isolates were confirmed to be of the genus Salmonella by performing bacteriological and biochemical tests. Briefly, all isolates were cultured onto XLD agar after which pure cultures were verified and stocked at this institute. Definitive identification was carried out using the API 20-E system and a separate urease test was also performed on all isolates. After confirmation of the genus, all isolates were prepared for antibiotic susceptibility testing and r-types were determined using sixteen antibiotics. Depending on the antibiotic resistance profiles, isolates were selected for …


The Development Of Functional Food Ingredients From Yeast Cell Wall Beta Glucans, Susan Keogh Jan 2006

The Development Of Functional Food Ingredients From Yeast Cell Wall Beta Glucans, Susan Keogh

Theses

The intracellular contents of spent yeast can be used to produce flavours and flavour enhancers. However there still remains after this process, a significant quantity of cell wall material, which makes up 20-25% of the dry weight of yeast biomass. A major component of the yeast cell wall is the polysaccharide P-glucan. This project involved the investigation of the extraction and characterisation of p-glucan as well as its evaluation as a functional food ingredient. A preparation of spent yeast p-glucan was obtained from two types of spent yeast species, Saccharomyces cervisiae (brewers yeast) and Kluyveromyces marxianus (dairy yeast) obtained from …


System Identification Of A Pasteurisation Process: A Comparison Of Direct And Indirect Methods, Niel Canty Jan 2006

System Identification Of A Pasteurisation Process: A Comparison Of Direct And Indirect Methods, Niel Canty

Theses

The primary focus of this research is to identify a linear model for a direct steam injection (DSI) pasteurisation process which is a component of a large-scale pilot evaporation process widely used in the dairy industry. The pasteurisation process has been identified as a key component of the evaporation process. The author believes that no previously published work has focused on identifying models for a DSI pasteurisation process which makes this work an original contribution to the area. The pasteurisation process can be modelled as a single-input, single-output (SISO) process with a measurable disturbance. Thus two transfer functions were required …