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Drosophila Alcohol Dehydrogenase: Developmental Studies On Cryptic Variant Lines, Gurbachan Miglani, Franklin Ampy
Drosophila Alcohol Dehydrogenase: Developmental Studies On Cryptic Variant Lines, Gurbachan Miglani, Franklin Ampy
Department of Biology Faculty Publications
Thirty-five cryptic variant lines were used to examine the mechanisms involved in genetic modulation of alcohol metabolism in Drosophila. Late third-instar larval, preemergence pupal, and adult stages cultured at 18 and 28 C were examined. Spectrophotometric analyses for native alcohol dehydrogenase (ADH) activity and residual ADH activity after treatment with guanidine hydrochloride and heat were performed. Differential response of cryptic variants to treatment with the denaturants during development suggested that this variation may have an adaptive significance.
Changes In Native Alcohol Dehydrogenase Activity Of Drosophila Upon Treatment With Guanidine Hydrochloride, Urea And Heat, Gurbachan Miglani, Franklin Ampy
Changes In Native Alcohol Dehydrogenase Activity Of Drosophila Upon Treatment With Guanidine Hydrochloride, Urea And Heat, Gurbachan Miglani, Franklin Ampy
Department of Biology Faculty Publications
Fifty-two isochromosomal lines ofDrosophila melanogaster were examined for the existence of additional genetic variations in ADH activity subsequent to treatment With guanidine hydrochloride, urea and heat. A wealth of hidden variation was discovered among and within the Mexican populations of the insect after treatment with the denaturants.
Statistical Analysis Of Cryptic Variation In Drosophila Alcohol Dehydrogenase, Gurbachan Miglani, Franklin Ampy
Statistical Analysis Of Cryptic Variation In Drosophila Alcohol Dehydrogenase, Gurbachan Miglani, Franklin Ampy
Department of Biology Faculty Publications
Statistical analysis indicated that mean alcohol dehydrogenase (ADH) activity levels within ADH1 and ADH11 isochromosomal lines varied significantly among the Mexican populations ofDrosophila melanogaster used. Also as indicated by coefficient of variation values for ADH activity, the relative amount of genetic variation differed among and within the ADH1 and ADH11 strains examined. The quantitative nature of the differences in ADH activity supported the concept of the additive gene action of the alcohol dehydrogenase (Adh) locus. The manner in which our isochromosomal lines were constructed suggested that genes regulating ADH activity inD. melanogaster were located on the second chromosomes.
Fungal Metabolite From Members Of The Genus Rhizopus, D Thompson, A Smalley, Broderick Eribo
Fungal Metabolite From Members Of The Genus Rhizopus, D Thompson, A Smalley, Broderick Eribo
Department of Biology Faculty Publications
A fluorescent metabolite present in seven members of the genus Rhizopus was isolated. This compound appeared green before spray treatment and purple after spray treatment with p-anisaldehyde in visible light. Subsequent purification and structural elucidation of the isolated compound yielded 1-[2,6,10,14-tetramethyl-17-carbomethyl heptadecyl]-1-[2,6,10,14-tetramethyl-17-methanoyl heptadecyl]-benzene.