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Changes In Some Blood Biochemical And Haematological Parameters In Goats After Aminoglycoside And Aminocyclitol Treatment At Therapeutic Doses, Toncho Dinev, Dimitrinka Zapryanova, Lubomir Lashev
Changes In Some Blood Biochemical And Haematological Parameters In Goats After Aminoglycoside And Aminocyclitol Treatment At Therapeutic Doses, Toncho Dinev, Dimitrinka Zapryanova, Lubomir Lashev
Turkish Journal of Veterinary & Animal Sciences
The aim of the present study was to determine the changes in some blood biochemical and haematological parameters in healthy female goats after a 5-day parenteral treatment with gentamicin (4 mg/kg), tobramycin (5 mg/kg), amikacin (10 mg/kg), kanamycin (10 mg/kg), apramycin (20 mg/kg), and spectinomycin (20 mg/kg). The results indicated that aminoglycosides caused more severe alterations than aminocyclitols, especially on those parameters related to renal function. There was a tendency toward a rise in plasma creatinine and urea levels after aminoglycoside treatment, as well as a rise in urea levels after aminocyclitol administration. These antibiotics caused decreases in plasma or …