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University of the Pacific Theses and Dissertations

1977

Adenosine triphosphatase

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The Partial Purification And Characterization Of A Soluble Activator Of The Cation Transport Adenosinetriphosophatase In Bovine Caudate Nucleus, Paul Culver Jan 1977

The Partial Purification And Characterization Of A Soluble Activator Of The Cation Transport Adenosinetriphosophatase In Bovine Caudate Nucleus, Paul Culver

University of the Pacific Theses and Dissertations

To many investigators, these observations suggested the existence of a molecular “pump” mechanism responsible for the maintenance of the ionic gradients. Extensive research over the last twenty years has resulted in the assignment of this role to the magnesium-dependent, sodium- and potassium-stimulated adenosine triphosphatase, first reported by Skou in 1957. This membrane-bound enzyme is the subject of the research presented in this thesis.