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University of the Pacific Theses and Dissertations

1973

Cytology Research

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The Effects Of Aging And Transformation On The Dna, Rna, Protein, And Hydroxyproline Content Of Fibroblasts (Wi 38) In Culture, James Michael Eichner Jan 1973

The Effects Of Aging And Transformation On The Dna, Rna, Protein, And Hydroxyproline Content Of Fibroblasts (Wi 38) In Culture, James Michael Eichner

University of the Pacific Theses and Dissertations

The study of the aging process is the investigation as to how the passage of time affects cells, organs, and organisms. Aging is a very complex and incompletely understood phenomenon. This is reflected by the number of theories attributing aging to a variety of causative factors such as: (1) the somatic mutations occurring spontaneously or produced by ionizing radiation, which are thought to have some effect on again but are not responsible for the normal process; (2) the alteration of macromolecules as the cells of an organism age forming neoantigens and functioning in the autoimmune reactions; the Cross-linkage theory which …