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The Effect Of Haloxon And Thiabendazole On The Free-Living Stages Of Haemonchus Contortus, Gary Mccallister

Theses and Dissertations

This study was undertaken to determine the effect of thiabendazole and haloxon on the free-living stages of Haemonchus contortus and to determine the suitability of the free-living stages for their use in primary drug evaluation for chemotherapy or for chemical control of free-living stages. Cleaned unembryonated ova, embryonated ova, first-, second-, third-, and exsheathed third-stage larvae were exposed to suspensions of 5.0%, 1.0%, 0.5%, 0.25%, 0.12%, 0.05%, and water soluble concentrations of each drug for exposure times of 0.25, 0.50, 1.0, 2.0, 4.0, 8.0, and 16.0 hours at pH 7.0 and 25° C. Survival was assessed by observing any subsequent …