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Theses

Theses/Dissertations

2006

Diagnosis

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Full-Text Articles in Life Sciences

Quantification Of Mrna Expression Of Her2/Neu, Estrogen Receptors Eralpha And Erbeta, And Progesterone Receptor Using Real-Time Reverse Transcription Pcr In Small Tumor Biopsies, In Human Breast Cancer, Evonne Marie. Mc Cabe Jan 2006

Quantification Of Mrna Expression Of Her2/Neu, Estrogen Receptors Eralpha And Erbeta, And Progesterone Receptor Using Real-Time Reverse Transcription Pcr In Small Tumor Biopsies, In Human Breast Cancer, Evonne Marie. Mc Cabe

Theses

Early detection is an effective means of reducing cancer mortality. Early detection greatly improves treatment options and the chances for successful treatment. The prognosis for patients with breast cancer is determined by well-established biological features associated with biological aggressiveness, histological grade, tumour size, and nodal involvement. Breast cancer results from multiple genetic abnormalities, and cellular differentiation, tumour growth, and metastatic potential are the end result of these changes. Identification of molecular changes is of considerable value in enhancing the accuracy of prognostic indices, and more importantly, it may indicate various changes as putative targets for therapy. In recent years a …