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Legacy Theses & Dissertations (2009 - 2024)

Theses/Dissertations

2017

Amyloid beta-protein

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Protein Aggregation As Hallmark Of Neurodegenerative Diseases, Viktoriia Stroilo Jan 2017

Protein Aggregation As Hallmark Of Neurodegenerative Diseases, Viktoriia Stroilo

Legacy Theses & Dissertations (2009 - 2024)

Neurodegenerative diseases like Alzheimer’s, Parkinson’s, Huntington’s, Amyotrophic Lateral Sclerosis and Prion Diseases tend to have similar cellular and molecular mechanisms of protein aggregation and inclusion body formation. These processes suggest common mechanisms of pathogenesis. Similarities in structure, mechanism of formation and physiological effects of protein aggregates in neurodegenerative diseases may lead to development of common preventative or therapeutic strategies.