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Full-Text Articles in Life Sciences
Gender Differences, Vitamin B6, Polyunsaturated Fatty Acids, And Inflammation-Related Diseases, Hyojung Kim
Gender Differences, Vitamin B6, Polyunsaturated Fatty Acids, And Inflammation-Related Diseases, Hyojung Kim
FIU Electronic Theses and Dissertations
Vitamin B6-restricted diets and low plasma pyridoxal 5'-phosphate (PLP) status altered plasma polyunsaturated fatty acids (PUFA) compositions. The relationship of aging with vitamin B6 status and PUFA metabolism is poorly understood. This dissertation explored the association between vitamin B6 intake and status and plasma PUFA in US young/middle-aged adults and in older adults from NHANES 2003-2004. Future research plans will examine the relationships among vitamin B6, PUFA, inflammatory diseases, including chronic liver diseases; however, there is a gap in plasma PLP data in the Miami Adult Studies in HIV (MASH) cohort data on these relationships. Thus, the relationship between substance …
Exposure To Estrogenic Endocrine Disrupting Chemicals And Brain Health, Mark Preciados
Exposure To Estrogenic Endocrine Disrupting Chemicals And Brain Health, Mark Preciados
FIU Electronic Theses and Dissertations
The overall objective of this dissertation was to examine exposures to the estrogenic endocrine disrupting chemicals (EEDCs), phthalates, bisphenol-A (BPA), and the metalloestrogens cadmium (Cd), arsenic (As), and manganese (Mn) in an older geriatric aged-population and examine associations with brain health. Given the evidence that EEDCs affect brain health and play a role in the development of cognitive dysfunction and neurodegenerative disease, and the constant environmental exposure through foods and everyday products has led this to becoming a great public health concern. Using a bioinformatic approach to find nuclear respiratory factor 1 (NRF1) gene targets involved in mitochondrial dysfunction, that …