Life Sciences Commons^™

An Efficient Pipeline To Generate Data For Studies In Plastid Population Genomics And Phylogeography, Brendan F. Kohrn, Jessica M. Persinger, Mitchell B. Cruzan

Biology Faculty Publications and Presentations

Premise of the study: Seed dispersal contributes to gene flow and is responsible for colonization of new sites and range expansion. Sequencing chloroplast haplotypes offers a way to estimate contributions of seed dispersal to population genetic structure and enables studies of population history. Whole‐genome sequencing is expensive, but resources can be conserved by pooling samples. Unfortunately, haplotype associations among single‐nucleotide polymorphisms (SNPs) are lost in pooled samples, and treating SNP allele frequencies as independent markers provides biased estimates of genetic structure.

Methods: We developed sampling methodologies and an application, CallHap, that uses a least‐squares algorithm to evaluate the fit between …

Editorial: Genetics, Genomics And –Omics Of Thermophiles, Kian Mau Goh, Kok-Gan Chan, Rajesh Kumar Sani, Edgardo Ruben Donati, Anna-Louise Reysenbach

Biology Faculty Publications and Presentations

Thermophilic Archaea and Bacteria occupy heated environments. Advancement of next-generation sequencing (NGS), single-cell analyses, and combinations of –omics and microscopic technologies have resulted in the discovery of new thermophiles. This e-book consists of a review, and 10 original articles authored by 94 authors. The main aim of this Research Topic of Frontiers in Microbiology was to provide a platform for researchers to describe recent findings on the ecology of thermophiles using NGS, functional genomics, comparative genomics, gene evolution, and extremozyme discovery.