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Full-Text Articles in Life Sciences
The Yeast Hex3·Slx8 Heterodimer Is A Ubiquitin Ligase Stimulated By Substrate Sumoylation, Yang Xie, Oliver Kerscher, Mary B. Kroetz, Heather F. Mcconchie, Patrick Sung, Mark Hochstrasser
The Yeast Hex3·Slx8 Heterodimer Is A Ubiquitin Ligase Stimulated By Substrate Sumoylation, Yang Xie, Oliver Kerscher, Mary B. Kroetz, Heather F. Mcconchie, Patrick Sung, Mark Hochstrasser
Arts & Sciences Articles
Hex3 and Slx8 are Saccharomyces cerevisiae proteins with important functions in DNA damage control and maintenance of genomic stability. Both proteins have RING domains at their C termini. Such domains are common in ubiquitin and ubiquitin-like protein ligases (E3s), but little was known about the molecular functions of either protein. In this study we identified HEX3 as a high-copy suppressor of a temperature-sensitive small ubiquitin-related modifier (SUMO) protease mutant, ulp1ts, suggesting that it may affect cellular SUMO dynamics. Remarkably, even a complete deletion of ULP1 is strongly suppressed. Hex3 forms a heterodimer with Slx8. We found that the Hex3·Slx8 …
Characteristics Of Vesicomyid Clams And Their Environment At The Blake Ridge Cold Seep, South Carolina, Usa, Randolph Chambers
Characteristics Of Vesicomyid Clams And Their Environment At The Blake Ridge Cold Seep, South Carolina, Usa, Randolph Chambers
Arts & Sciences Articles
Spatial distributions and patchiness of dominant megafaunal invertebrates in deep-sea seep environments may indicate heterogeneities in the flux of reduced chemical compounds. At the Blake Ridge seep off South Carolina, USA, the invertebrate assemblage includes dense populations of live vesicomyid clams (an undescribed species) as well as extensive clam shell beds (i.e. dead clams). In the present study, we characterized clam parameters (density, size-frequency distribution, reproductive condition) in relation to sulfur chemistry (sulfide and sulfate concentrations and isotopic compositions, pyrite and elemental sulfur concentrations) and other sedimentary metrics (grain size, organic content). For clams >5 mm, clam density was highest …
Documentation Of Infanticide And Cannibalism In Bald Eagles, A. C. Markham, B. D. Watts
Documentation Of Infanticide And Cannibalism In Bald Eagles, A. C. Markham, B. D. Watts
Arts & Sciences Articles
"Non-kin infanticide, the killing of dependent young by unrelated conspecifics, occurs in a wide array of taxonomic groups including mammals, insects, fish, and birds (Hrdy 1979, Hrdy and Hausfater 1984). Several hypotheses have been proposed to explain this behavior including the removal of potential competitors to gain access to limited resources such as nesting territories and food (Hrdy 1979)..."