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William & Mary

Arts & Sciences Articles

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2006

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Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Oncogenic Conversion Of The Thyroid Hormone Receptor By Altered Nuclear Transport, Ghislain M.C. Bonamy, Lizabeth A. Allison Jan 2006

Oncogenic Conversion Of The Thyroid Hormone Receptor By Altered Nuclear Transport, Ghislain M.C. Bonamy, Lizabeth A. Allison

Arts & Sciences Articles

Nuclear receptors (NRs) are transcription factors whose activity is modulated by ligand binding. These receptors are at the core of complex signaling pathways and act as integrators of many cellular signals. In the last decade our understanding of NRs has greatly evolved. In particular, regulation of NR subcellular dynamics has emerged as central to their activity. Research on the subcellular distribution of the thyroid hormone receptor (TR) has revealed new dimensions in the complexity of NR regulation, and points to the possibility that NR mislocalization plays a key role in oncogenesis. For many years, TR was thought to reside exclusively …


Kinosternon Subrubrum Subrubrum (Eastern Mud Turtle) Predator Escape, Joseph C. Mitchell, A. C. Markham, B. D. Watts Jan 2006

Kinosternon Subrubrum Subrubrum (Eastern Mud Turtle) Predator Escape, Joseph C. Mitchell, A. C. Markham, B. D. Watts

Arts & Sciences Articles

"Known avian predators of Kinosternon subrubrum include crows and eagles (Ernst et al. 1994. Turtles of the United States and Canada, Smithsonian Inst. Press, Washington, DC; Mitchell 1994. The Reptiles of Virginia, Smithsonian Inst. Press, Washington, DC)..."