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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
An Entrepreneurial Approach To Librarianship, Flora G. Shrode, Jennifer R. Duncan, Wendy Holliday
An Entrepreneurial Approach To Librarianship, Flora G. Shrode, Jennifer R. Duncan, Wendy Holliday
Flora Shrode
Librarians from Utah State University explain recent efforts to encourage subject librarians to take a more holistic view of their roles. We are shifting from a traditional emphasis primarily on collection development and refocusing on natural connections between collections, instruction, liaison, and reference service. The poster provides background about Utah State University’s situation and explains our approach to analyzing local needs and culture to inform development of a new organizational structure. We describe our vision of subject librarianship, the process by which we assessed librarians’ ideas and goals for performing as subject librarians, and the actions we are taking to …
Effect Of Dipterinyl Calcium Pentahydrate On Hepatitis B Virus Replication In Transgenic Mice, P Moheno, John D. Morrey, D Fuchs
Effect Of Dipterinyl Calcium Pentahydrate On Hepatitis B Virus Replication In Transgenic Mice, P Moheno, John D. Morrey, D Fuchs
John D. Morrey
Dipterinyl calcium pentahydrate (DCP) has previously been shown to inhibit MDA-MB-231 human breast cancer xenographs in nude mice in a manner correlated with increases in plasma IL-12 and IL-4 concentrations, and decreases in plasma IL-6 levels. DCP also inhibits indoleamine 2,3-dioxygenase (IDO), an immuno-inhibitory enzyme, in human PBMCs (Peripheral Blood Mononuclear Cells).
Assessing Changes In Vascular Permeability In A Hamster Model Of Viral Hemorrhagic Fever, B B. Gowen, J G. Julander, N R. London, M H. Wong, D Larson, John D. Morrey, D Y. Li, M Bray
Assessing Changes In Vascular Permeability In A Hamster Model Of Viral Hemorrhagic Fever, B B. Gowen, J G. Julander, N R. London, M H. Wong, D Larson, John D. Morrey, D Y. Li, M Bray
John D. Morrey
A number of RNA viruses cause viral hemorrhagic fever (VHF), in which proinflammatory mediators released from infected cells induce increased permeability of the endothelial lining of blood vessels, leading to loss of plasma volume, hypotension, multi-organ failure, shock and death. The optimal treatment of VHF should therefore include both the use of antiviral drugs to inhibit viral replication and measures to prevent or correct changes in vascular function. Although rodent models have been used to evaluate treatments for increased vascular permeability (VP) in bacterial sepsis, such studies have not been performed for VHF.
Development Of A New Tacaribe Arenavirus Infection Model And Its Use To Explore Antiviral Activity Of A Novel Aristeromycin Analog, B B. Gowen, M H. Wong, D Larson, W Ye, K H. Jung, E J. Sefing, R Skirpstunas, D F. Smee, John D. Morrey, S W. Schneller
Development Of A New Tacaribe Arenavirus Infection Model And Its Use To Explore Antiviral Activity Of A Novel Aristeromycin Analog, B B. Gowen, M H. Wong, D Larson, W Ye, K H. Jung, E J. Sefing, R Skirpstunas, D F. Smee, John D. Morrey, S W. Schneller
John D. Morrey
A growing number of arenaviruses can cause a devastating viral hemorrhagic fever (VHF) syndrome. They pose a public health threat as emerging viruses and because of their potential use as bioterror agents. All of the highly pathogenic New World arenaviruses (NWA) phylogenetically segregate into clade B and require maximum biosafety containment facilities for their study. Tacaribe virus (TCRV) is a nonpathogenic member of clade B that is closely related to the VHF arenaviruses at the amino acid level. Despite this relatedness, TCRV lacks the ability to antagonize the host interferon (IFN) response, which likely contributes to its inability to cause …
Effects Of The Combination Of Favipiravir (T-705) And Oseltamivir On Influenza A Virus Infections In Mice, D F. Smee, B L. Hurst, M H. Wong, K W. Bailey, E B. Tarbet, John D. Morrey, Y Furuta
Effects Of The Combination Of Favipiravir (T-705) And Oseltamivir On Influenza A Virus Infections In Mice, D F. Smee, B L. Hurst, M H. Wong, K W. Bailey, E B. Tarbet, John D. Morrey, Y Furuta
John D. Morrey
Favipiravir (T-705 [6-fluoro-3-hydroxy-2-pyrazinecarboxamide]) and oseltamivir were combined to treat influenza virus A/NWS/33 (H1N1), A/Victoria/3/75 (H3N2), and A/Duck/MN/1525/81 (H5N1) infections. T-705 alone inhibited viruses in cell culture at 1.4 to 4.3 µM. Oseltamivir inhibited these three viruses in cells at 3.7, 0.02, and 0.16 µM and in neuraminidase assays at 0.94, 0.46, and 2.31 nM, respectively. Oral treatments were given twice daily to mice for 5 to 7 days starting, generally, 24 h after infection. Survival resulting from 5 days of oseltamivir treatment (0.1 and 0.3 mg/kg/day) was significantly better in combination with 20 mg/kg of body weight/day of T-705 against …
Gps-‐‐Basedmeasurements Of Backcountry Visitors In Parks And Protected Areas: Examples Of Methods And Applications From Three Case Studies, A. D'Antonio, Christopher Monz, S. Lawson, P. Newman
Gps-‐‐Basedmeasurements Of Backcountry Visitors In Parks And Protected Areas: Examples Of Methods And Applications From Three Case Studies, A. D'Antonio, Christopher Monz, S. Lawson, P. Newman
Christopher Monz
No abstract provided.
Bear River Watershed: Its Role In Maintaining The Bear River Migratory Bird Refuge, Richard E. Toth, Thomas J. Edwards Jr, Adam L. Perschon, Danny C. White
Bear River Watershed: Its Role In Maintaining The Bear River Migratory Bird Refuge, Richard E. Toth, Thomas J. Edwards Jr, Adam L. Perschon, Danny C. White
Richard E. Toth
No abstract provided.
Contrasting Effects Of Cattle And Wildlife On The Vegetation Development Of A Savanna Landscape Mosaic, Kari E. Veblen
Contrasting Effects Of Cattle And Wildlife On The Vegetation Development Of A Savanna Landscape Mosaic, Kari E. Veblen
Kari E. Veblen
Through their effects on plant communities, herbivores can exert strong direct and indirect effects on savanna ecosystems and have the potential to create and maintain savanna landscape heterogeneity. Throughout much of sub‐Saharan Africa, periodic creation and abandonment of livestock corrals leads to landscape mosaics of long‐term ecosystem hotspots that attract both cattle and large ungulate wildlife. The development and maintenance of vegetation in these types of hotspots may be controlled in part by herbivory. Cattle and wildlife may have different, potentially contrasting effects on plant succession and plant–plant interactions. We ask how cattle and wild herbivores affect the maintenance and …
Meta-Analytic Review Of Corridor Effectiveness : Una Revisión Meta‐Analítica De La Efectividad De Los Corredores, Karen H. Beard
Meta-Analytic Review Of Corridor Effectiveness : Una Revisión Meta‐Analítica De La Efectividad De Los Corredores, Karen H. Beard
Karen H. Beard
Using corridors for conservation is increasing despite a lack of consensus on their efficacy. Specifically, whether corridors increase movement of plants and animals between habitat fragments has been addressed on a case-by-case basis with mixed results. Because of the growing number of well-designed experiments that have addressed this question, we conducted a meta-analysis to determine whether corridors increase movement; whether corridor effectiveness differs among taxa; how recent changes in experimental design have influenced findings; and whether corridor effectiveness differs between manipulative and natural experiments. To conduct our meta-analysis, we analyzed 78 experiments from 35 studies using a conservative hierarchical Bayesian …