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Evaluation Of Pro-Inflammatory Biomarkers As Potential Early Indicators Of Acute Respiratory Distress Syndrome (Ards), Makda Solomon Gebre
Evaluation Of Pro-Inflammatory Biomarkers As Potential Early Indicators Of Acute Respiratory Distress Syndrome (Ards), Makda Solomon Gebre
Undergraduate Honors Capstone Projects
Infections with the 2009 pandemic influenza A(HlNl) virus often leads to acute respiratory distress syndrome (ARDS) in high-risk patients. In these patients, ARDS has a mortality rate of 40-50 % [1]. Patients may die before any intervention is possible since there are few if any early biomarkers that are indicative of ARDS and can be used for diagnosis. In a search for biomarkers that signal early disease progression in mice, multiple acute phase proteins involved with inflammatory responses to infectious stimuli were proposed. Three biomarkers were evaluated for this project. These included C-reactive protein (CRP), Serum Amyloid A (SAA) and …