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University of Tennessee, Knoxville
Faculty Publications and Other Works -- Ecology and Evolutionary Biology
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Mutrack: A Genome Analysis System For Large-Scale Mutagenesis In The Mouse, Erich J. Baker, Leslie Galloway, Barbara Jackson, Denise Schmoyer, Jay Snoddy
Mutrack: A Genome Analysis System For Large-Scale Mutagenesis In The Mouse, Erich J. Baker, Leslie Galloway, Barbara Jackson, Denise Schmoyer, Jay Snoddy
Faculty Publications and Other Works -- Ecology and Evolutionary Biology
Abstract
Background
Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanning genetics, molecular biology, histology, and behavioral science, researchers may examine, with varying degrees of granularity, numerous phenotypic aspects of mutant mouse strains directly pertinent to human disease states. Success of these and other genome-wide endeavors relies on a well-structured bioinformatics core that brings together investigators from widely dispersed institutions and enables them to seamlessly integrate data, observations and discussions.
Description
MuTrack was developed as the bioinformatics core for a large mouse phenotype screening effort. It is …