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University of Nebraska - Lincoln

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

2021

Antibacterial

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Antibacterial Activities Of Nepetalactones Against Public Health-Related Pathogens, Anuradha Ghosh, Enya V. Zhu, Haichuan Wang, Ludek Zurek, Junwei J. Zhu Jan 2021

Antibacterial Activities Of Nepetalactones Against Public Health-Related Pathogens, Anuradha Ghosh, Enya V. Zhu, Haichuan Wang, Ludek Zurek, Junwei J. Zhu

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The antimicrobial activities of (Z,E)- and (E,Z)-nepetalactones, 2 major compositional compounds from the essential oil of catnip (Nepeta cataria), were first discovered from fly larval development media studies with over 98% inhibition of bacterial growth. Further investigation demonstrated inhibition of the growth of various bacterial species of public health significance. Catnip oil showed antibacterial activity against 5 Gram-positive and 9 Gram-negative bacteria. The antimicrobial activity varied among the original essential oil from the plant and its major compositional compounds as a blended mixture or an individual compound. Growth inhibition was observed against 5 Neisseria species, with particularly strong inhibition against …