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School of Biological Sciences: Dissertations, Theses, and Student Research
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Articles 1 - 8 of 8
Full-Text Articles in Life Sciences
Polerovirus Genomic Variation And Mechanisms Of Silencing Suppression By P0 Protein, Natalie Holste
Polerovirus Genomic Variation And Mechanisms Of Silencing Suppression By P0 Protein, Natalie Holste
School of Biological Sciences: Dissertations, Theses, and Student Research
The family Luteoviridae consists of three genera: Luteovirus, Enamovirus, and Polerovirus. The genus Polerovirus contains 32 virus species. All are transmitted by aphids and can infect a wide variety of crops from cereals and wheat to cucurbits and peppers. However, little is known about how this wide range of hosts and vectors developed. In poleroviruses, aphid transmission and virion formation is mediated by the coat protein read-through domain (CPRT) while silencing suppression and phloem limitation is mediated by Protein 0 (P0)—a protein unique to poleroviruses. P0 gives poleroviruses a great advantage amongst plant viruses and diversifies polerovirus species, but the …
Metagenomic, Viral And Host Genetic Analyses Of Congenital Tremor In Pigs, Kylee Sutton
Metagenomic, Viral And Host Genetic Analyses Of Congenital Tremor In Pigs, Kylee Sutton
School of Biological Sciences: Dissertations, Theses, and Student Research
The Pestivirus genus contains several viral species having a major impact on the livestock species. While there were only four major pestiviral species for a time, recent metagenomic sequencing approaches identified additional species, such as atypical porcine pestivirus (APPV). Congenital tremor was first identified almost a hundred years ago and since still has an impact on swine health. There are two main types of congenital tremor, type A and B, with type A congenital tremor further subcategorized based on causative agent. Until recently, type A-II congenital tremor did not have a known cause. Recent viral sequencing of affected samples, including …
Bioinformatic Analysis Of The Gut Microbiota Derived From The Oil Fly Helaeomyia Petrolei From The La Brea Tar Pits, Brian Dillard
Bioinformatic Analysis Of The Gut Microbiota Derived From The Oil Fly Helaeomyia Petrolei From The La Brea Tar Pits, Brian Dillard
School of Biological Sciences: Dissertations, Theses, and Student Research
In the early 1930s, Thorpe a prominent entomologist, called for more research into Helaeomyia petrolei larva. These larvae live in the Californian La Brea tar pits where they are exposed to large amounts of polyaromatic hydrocarbons. Molecules like anthracene, phenanthrene, and toluene which should be highly toxic to both the oil fly larvae and its enteric bacteria. This extremophilic gut microbiome has yet to be studied using current day next gen sequencing and bioinformatic techniques. In fact, since Thorpe’s work in the 1930s, there have been only two publications characterizing the oil fly larvae. Both in the early 2000s by …
The Relationship Between The Cervical Microbiome And Cervical Cancer Risk In Sub-Saharan Africa, Cameron Klein
The Relationship Between The Cervical Microbiome And Cervical Cancer Risk In Sub-Saharan Africa, Cameron Klein
School of Biological Sciences: Dissertations, Theses, and Student Research
Despite ongoing efforts, sub-Saharan Africa faces a higher cervical cancer burden than anywhere else in the world. Besides HPV infection, definitive factors of cervical cancer are still unclear. Dysbiosis of the cervicovaginal microbiota, particularly involving sexually transmitted infections, is associated with increased cervical cancer risk. Notably, HIV infection, which is prevalent in sub-Saharan Africa, greatly increases risk of cervicovaginal dysbiosis and cervical cancer. To better understand and address cervical cancer in sub-Saharan Africa, a better understanding of the regional cervicovaginal microbiome is required. In this study, I establish the relationship between cervical cancer, HPV, HIV, cervicovaginal infections, and the cervicovaginal …
Prey Selection By Birds Of Prey, Anisha Pokharel
Prey Selection By Birds Of Prey, Anisha Pokharel
School of Biological Sciences: Dissertations, Theses, and Student Research
Prey selection is key to determine predator prey interaction and understanding the complexity of food web structure. In this thesis, we used two different approaches to understanding prey selection by North American birds of prey. Using a conventional method, in Chapter 1 we compared pellet analysis and trapping data to assess patterns of prey selection of barn owls in western Nebraska. Microtus spp. comprised 55.8% of the prey items in the barn owl’s diet. The proportion of several prey types in the diet were significantly different from the expected proportion based on trapping. This pattern may indicate barn owls actively …
Functions Of Vocal Mimicry In The Complex Song Of The European Starling, Sturnus Vulgaris, Maria Goller
Functions Of Vocal Mimicry In The Complex Song Of The European Starling, Sturnus Vulgaris, Maria Goller
School of Biological Sciences: Dissertations, Theses, and Student Research
Vocal learning is an ability that has only evolved in a handful of taxa. Songbirds learn their songs, and some species have flexible learning in which they not only incorporate species-specific sounds, but heterospecific and/or environmental sounds as well. The functions of vocal mimicry are still unknown for many species and studying mimicry can teach us about the variation within the song learning process. In this thesis, I focused on five hypotheses on how mimicry could function in sexual selection. The repertoire size hypothesis suggests that selection for larger repertoire sizes allows mimicry to occur because imitation can increase repertoire …
Dgts Production As A Phosphate Starvation Response In The Human Fungal Pathogen Candida Albicans, Caleb Wehling
Dgts Production As A Phosphate Starvation Response In The Human Fungal Pathogen Candida Albicans, Caleb Wehling
School of Biological Sciences: Dissertations, Theses, and Student Research
Betaine lipids are a class of membrane lipids with betaine head groups. Three betaine lipids are known - diacylglyceryltrimethylhomoserine (DGTS), diacylglycerylhydroxymethylalanine (DGTA), and diacylglycerylcarboxymethylcholine (DGCC). Betaine lipids are most common in algae, although DGTS, the most common betaine lipid, is also found in many bacteria and fungi. Organisms which produce betaine lipids (especially DGTS) often don’t produce phosphatidylcholine (PtdCho), and DGTS structure resembles PtdCho structure without any phosphorous, leading to the hypothesis that betaine lipids may substitute for phospholipids in some organisms. This has been confirmed by discoveries that some organisms are capable of switching their membrane composition from PtdCho …
Identification Of The Kaposi's Sarcoma-Associated Herpesvirus (Kshv) Surface Glycoprotein Targets Of Human Kshv-Specific Neutralizing Antibody Responses, Yasaman Mortazavi
Identification Of The Kaposi's Sarcoma-Associated Herpesvirus (Kshv) Surface Glycoprotein Targets Of Human Kshv-Specific Neutralizing Antibody Responses, Yasaman Mortazavi
School of Biological Sciences: Dissertations, Theses, and Student Research
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the etiological agent of Kaposi’s sarcoma (KS), and is also associated with two B cell malignancies, primary effusion lymphoma and multicentric Castleman's disease. The distribution of KSHV varies globally with high prevalence in some areas of sub-Saharan Africa (SSA), where seroprevalence can be as high as 80%. It is estimated that nearly 44,000 new cases of KS emerge annually globally, with the highest incidents occurring in Africa, where KSHV is endemic. Currently, there is no prophylactic vaccine against KSHV, and efforts to develop prophylactic vaccines have been limited. …