Life Sciences Commons^™

Dietary Antioxidants Impact Ddt Resistance In Drosophila Melanogaster, Gamal A. M. Abdu-Allah, Keon-Mook Seong, Omprakash Mittapalli, James Adebayo Ojo, Weilin Sun, Omar Posos-Parra, David Mota-Sanchez, John M. Clark, Barry R. Pittendrigh

Entomology Faculty Publications

Insects experience a diversity of subtoxic and/or toxic xenobiotics through exposure to pesticides and, in the case of herbivorous insects, through plant defensive compounds in their diets. Many insects are also concurrently exposed to antioxidants in their diets. The impact of dietary antioxidants on the toxicity of xenobiotics in insects is not well understood, in part due to the challenge of developing appropriate systems in which doses and exposure times (of both the antioxidants and the xenobiotics) can be controlled and outcomes can be easily measured. However, in Drosophila melanogaster, a well-established insect model system, both dietary factors and …