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- Dr Myrna A Deseo (24)
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Articles 1 - 30 of 79
Full-Text Articles in Life Sciences
Arabidopsis Thaliana Ahl Family Modulates Hypocotyl Growth Redundantly By Interacting With Each Other Via The Ppc/Duf296 Domain, Jianfei Zhao, David Favero, Hao Peng, Michael Neff
Arabidopsis Thaliana Ahl Family Modulates Hypocotyl Growth Redundantly By Interacting With Each Other Via The Ppc/Duf296 Domain, Jianfei Zhao, David Favero, Hao Peng, Michael Neff
Jianfei Zhao
Long-Distance Translocation Of Photosynthates: A Primer [Review Article], Michael Knoblauch, Winfried S. Peters
Long-Distance Translocation Of Photosynthates: A Primer [Review Article], Michael Knoblauch, Winfried S. Peters
Winfried S. Peters
Phytochemical And Pharmacological Aspects Of Australian Bloodroots (Haemodora Spp.), Lei Liu, Myrna Deseo, D Thompson, Hans Wohlmuth, David Leach
Phytochemical And Pharmacological Aspects Of Australian Bloodroots (Haemodora Spp.), Lei Liu, Myrna Deseo, D Thompson, Hans Wohlmuth, David Leach
Dr Hans Wohlmuth
No abstract provided.
Phytochemistry And Pharmacology Of Volatile Components Of Plectranthus Graveolens R. Br., L Cyril, Myrna Deseo, G Buchbauer, P Forster, David Leach
Phytochemistry And Pharmacology Of Volatile Components Of Plectranthus Graveolens R. Br., L Cyril, Myrna Deseo, G Buchbauer, P Forster, David Leach
Dr Myrna A Deseo
No abstract provided.
Phytochemical And Pharmacological Aspects Of Australian Bloodroots (Haemodora Spp.), Lei Liu, Myrna Deseo, D Thompson, Hans Wohlmuth, David Leach
Phytochemical And Pharmacological Aspects Of Australian Bloodroots (Haemodora Spp.), Lei Liu, Myrna Deseo, D Thompson, Hans Wohlmuth, David Leach
Dr Myrna A Deseo
No abstract provided.
Compounds From Saccharum Officinarum L. As Leads For Anti-Diabetes Treatment, D Payne, David Leach, C Morris, M O'Shea, Lei Liu, Kellie Shepherd, Myrna Deseo
Compounds From Saccharum Officinarum L. As Leads For Anti-Diabetes Treatment, D Payne, David Leach, C Morris, M O'Shea, Lei Liu, Kellie Shepherd, Myrna Deseo
Dr Myrna A Deseo
No abstract provided.
Seed Biology Research And Conservation Of Eastern Australian Rainforest Diversity, K Hamilton, C Offord, P Cuneo, S Ashmore, Myrna Deseo
Seed Biology Research And Conservation Of Eastern Australian Rainforest Diversity, K Hamilton, C Offord, P Cuneo, S Ashmore, Myrna Deseo
Dr Myrna A Deseo
No abstract provided.
Gc Analysis Of Aqueous Plant Extracts, K Shepherd, V Westbrooke, Myrna Deseo
Gc Analysis Of Aqueous Plant Extracts, K Shepherd, V Westbrooke, Myrna Deseo
Dr Myrna A Deseo
No abstract provided.
Modulation Of Natural Killer Cell Activity By Water Soluble Polysaccharides From The Roots Of Asparagus Racemosus Linn, M Thakur, P Connellan, Myrna Deseo, Carol Morris, V Dixit
Modulation Of Natural Killer Cell Activity By Water Soluble Polysaccharides From The Roots Of Asparagus Racemosus Linn, M Thakur, P Connellan, Myrna Deseo, Carol Morris, V Dixit
Dr Myrna A Deseo
Asparagus racemosus L. (Fam. Liliaceae) is an ethno-pharmacologically acclaimed Ayurvedic medicinal plant [1]. The plant belongs to the category of 'Rasayana' i.e., plants possessing immunomodulatory and adaptogenic activity [2]. Although there have been claims on immune system potentiation by aqueous extracts of A. racemosus, there is a lack of information specifying the exact molecular mechanism and phytochemical components responsible for the immuno-stimulatory activity.
In the present study, an aqueous extract of A. racemosus (ARC) was further fractionated to isolate the polysaccharide fraction (ARP). The isolated polysaccharides (ARP) were characterized by enzymatic, size exclusion, GC-FID, and thin layer chromatographic analyses. …
Preliminary Investigation Into Milk Flavour, V Westbooke, H Smyth, K Shepherd, Carol Morris, B Granzin, Myrna Deseo
Preliminary Investigation Into Milk Flavour, V Westbooke, H Smyth, K Shepherd, Carol Morris, B Granzin, Myrna Deseo
Dr Myrna A Deseo
No abstract provided.
Preliminary Investigation Into The Phytochemical And Pharmacological Aspects Of Plectranthus Species, E Pasoski, L Marangattil, Myrna Deseo, David Leach, P Forster
Preliminary Investigation Into The Phytochemical And Pharmacological Aspects Of Plectranthus Species, E Pasoski, L Marangattil, Myrna Deseo, David Leach, P Forster
Dr Myrna A Deseo
No abstract provided.
Rainforest Seed Project, K Hamilton, C Offord, P Cuneo, S Ashmore, Myrna Deseo, K Shepherd
Rainforest Seed Project, K Hamilton, C Offord, P Cuneo, S Ashmore, Myrna Deseo, K Shepherd
Dr Myrna A Deseo
No abstract provided.
Preliminary Investigation Into The Phytochemical And Pharmacological Aspects Of Plecthrantus Sp. 'Hann Tableland', E Pasoski, Myrna Deseo, G Buchbauer, Lei Liu, P Forster, David Leach
Preliminary Investigation Into The Phytochemical And Pharmacological Aspects Of Plecthrantus Sp. 'Hann Tableland', E Pasoski, Myrna Deseo, G Buchbauer, Lei Liu, P Forster, David Leach
Dr Myrna A Deseo
No abstract provided.
Chemical Composition And Biological Activity Of The Essential Oils From Native Australian Callitris Species, Angela Oprava, David Leach, Karren Beattie, Paul Connellan, Paul Forster, Greg Leach, Gerhard Buchbauer, Kellie Shepherd, Myrna Deseo
Chemical Composition And Biological Activity Of The Essential Oils From Native Australian Callitris Species, Angela Oprava, David Leach, Karren Beattie, Paul Connellan, Paul Forster, Greg Leach, Gerhard Buchbauer, Kellie Shepherd, Myrna Deseo
Dr Myrna A Deseo
The chemical composition of the essential oil of the wood of the Australian native cypress Callitris endlicheri, C. intratropica and C. columellaris were determined by GCMS. The colour of the oils from C. endlicheri were yellow, yellow green and light green, whilst the distinct blue colour of the oil from C. intratropica was in keeping with its generic name ‘blue cypress oil'. The sesquiterpene alcohol guaiol (1) comprised >50% of the C. endlicheri oil. Significant differences were observed in components between the three accessions. In contrast, the oils of C. intratropica showed more subtle variations between collection …
Sugarcane Molasses – A Potential Source Of Anti-Diabetic Compounds, D Payne, R Taylor, Myrna Deseo, M O'Shea, N Masel, David Leach
Sugarcane Molasses – A Potential Source Of Anti-Diabetic Compounds, D Payne, R Taylor, Myrna Deseo, M O'Shea, N Masel, David Leach
Dr Myrna A Deseo
No abstract provided.
Chemical Variation In The Leaf Essential Oils Of Australian Corymbia Spp., Myrna Deseo, K Shepherd, M Abasolo, Mervyn Shepherd, D Lee
Chemical Variation In The Leaf Essential Oils Of Australian Corymbia Spp., Myrna Deseo, K Shepherd, M Abasolo, Mervyn Shepherd, D Lee
Dr Myrna A Deseo
No abstract provided.
Isolation And Identification Of Antioxidant Compounds From Carica Papaya L, E Jensen, A Larsen, David Leach, Myrna Deseo
Isolation And Identification Of Antioxidant Compounds From Carica Papaya L, E Jensen, A Larsen, David Leach, Myrna Deseo
Dr Myrna A Deseo
No abstract provided.
Conserving Australia's Unique Rainforest Fruits And Wild Relatives, Kim N Hamilton, Catherine A Offord, Peter Cuneo, Sarah E Ashmore, Myrna Deseo
Conserving Australia's Unique Rainforest Fruits And Wild Relatives, Kim N Hamilton, Catherine A Offord, Peter Cuneo, Sarah E Ashmore, Myrna Deseo
Dr Myrna A Deseo
Australian rainforests have many unique edible fruits including wild relatives of worldwide economically important species such as citrus and macadamia. One of the key risks of projected climate change is its effect on Eastern Australian rainforests. The interaction of climate change with other threats, such as weeds and habitat fragmentation, is thus likely to impact on already vulnerable environments such as the World Heritage listed Gondwana Rainforests of S. Queensland and N. New South Wales. Seed banking is a cost effective way of conserving unique and vulnerable diversity ex situ for utilisation (e.g., plant breeding and restoration programs). However, the …
Investigation Of A-Glucosidase Inhibitory Activity Of Wheat Bran And Germ, Lei Liu, Myrna Deseo, Carol Morris, Kelly Winter, David Leach
Investigation Of A-Glucosidase Inhibitory Activity Of Wheat Bran And Germ, Lei Liu, Myrna Deseo, Carol Morris, Kelly Winter, David Leach
Dr Myrna A Deseo
Postprandial hyperglycaemia is a primary risk factor in the development of Type 2 diabetes. α-Glucosidaseinhibitors that reduce postprandial hyperglycaemia have a key role in the treatment of Type 2 pre-diabetic states and also have the potential to reduce the progression to complications of diabetes. Epidemiological studies showed that risk for Type 2 diabetes mellitus was decreased with consumption of whole grains. Thebran and germ of whole wheat are major components of whole grain consumption and are widely accepted as important ingredients in many low glycaemic index (GI) foods. In this study, the α-glucosidaseinhibitoryactivity of wheatbran and germ was investigated. The …
Phytochemical Study Of Fagraea Spp. Uncovers A New Terpene Alkaloid With Anti-Inflammatory Properties1, Suciati, Lynette Lambert, Benjamin Ross, Myrna Deseo, Mary Garson
Phytochemical Study Of Fagraea Spp. Uncovers A New Terpene Alkaloid With Anti-Inflammatory Properties1, Suciati, Lynette Lambert, Benjamin Ross, Myrna Deseo, Mary Garson
Dr Myrna A Deseo
Phytochemical investigation of the stem bark of F. racemosa JACK ex WALL (Loganiaceae) from East Java, Indonesia, has resulted in the isolation of a new alkaloid fagraeoside along with the iridoid glycoside secologanoside. Fagraeoside may be derived from the condensation of secologanin with L-asparagine, and represents a rare example of a terpene alkaloid in which the amino acid component is non-aromatic. Investigation of three additional species ofFagraea provided known lignans, iridoid or secoiridoid glycosides, and flavanol-6-C-glucosides, thus it is likely that iridoid and secoiridoid glucosides are chemotaxonomic markers for the Fagraea genus. Fagraeoside inhibited the production of prostaglandin E2 in …
Characterization And In Vitro Immunomodulatory Screening Of Fructo-Oligosaccharides Of Asparagus Racemosus Willd, Mayank Thakur, Paul Connellan, Myrna Deseo, Carol Morris, Werner Praznik, Loeppert, Dixit
Characterization And In Vitro Immunomodulatory Screening Of Fructo-Oligosaccharides Of Asparagus Racemosus Willd, Mayank Thakur, Paul Connellan, Myrna Deseo, Carol Morris, Werner Praznik, Loeppert, Dixit
Dr Myrna A Deseo
Asparagus racemosus Linn. (Fam. Liliaceae) is an ethno-pharmacologically acclaimed Ayurvedic medicinal plant. In the present study, aqueous extract of A. racemosus (ARC) was fractionated and screened for the polysaccharide fraction (ARP). The characterization was done by enzymatic, Size Exclusion, gas chromatography with flame ionization detector (GC–FID), high pressure anion exchange chromatography (HPAEC) and thin layer chromatographic analyses. Phyto-chemical evaluation confirmed the presence of 26.7% of 2 → 1 linked fructo-oligosaccharides (FOS). They have a degree of polymerization (DP) of nearly 7–8. Cytotoxicity evaluation on P388 cell lines was consistent with low cytotoxicity of the extracts. In vitroNatural Killer (NK) cell …
Genomics And Metabolomics For New Plant Products, Daniel Waters, Peter Bundock, Hans Wohlmuth, Myrna Deseo, Lei Liu, Frances Shapter, Agnelo Furtado
Genomics And Metabolomics For New Plant Products, Daniel Waters, Peter Bundock, Hans Wohlmuth, Myrna Deseo, Lei Liu, Frances Shapter, Agnelo Furtado
Dr Myrna A Deseo
No abstract provided.
Novel Polyketide Metabolites From Streptomyces Rimosus Mutant Strain R1059, Myrna Deseo, Iain Hunter, Peter Waterman
Novel Polyketide Metabolites From Streptomyces Rimosus Mutant Strain R1059, Myrna Deseo, Iain Hunter, Peter Waterman
Dr Myrna A Deseo
Three novel polyketide metabolites were isolated from laboratory-scale fermentation of the Streptomyces rimosus mutant strain R1059. Structural elucidation of the compounds was based on NMR experiments. The compounds were characterized as naphthalene derivatives: (rel)-4,8-dihydroxy-3-hydroxymethyl-4-methyl-1,2,3,4-tetrahydronaphthalene-1-one (1), 4,8-dihydroxy-3-hydroxymethyl-4-methyl-1,4-dihydronaphthalene-1-one (2) and (rel)-4,8-dihydroxy-3-O-[-glucopyranosyl]hydroxymethyl-4-methyl-1,2,3,4-tetrahydronaphthalene-1-one (3). The compounds isolated appear to be derived via a shorter polyketide backbone than oxytetracycline (4), the normal end-product made by the parent of this strain. Compound 3 was the glucoside of 1 and must be formed as a post-PKS reaction by the activation of a glycosyl transferase, which has not been reported in this species before.
Immunomodulatory Polysaccharide From Chlorophytum Borivilianum Roots, Mayank Thakur, Paul Connellan, Myrna Deseo, Carol Morris, V Dixit
Immunomodulatory Polysaccharide From Chlorophytum Borivilianum Roots, Mayank Thakur, Paul Connellan, Myrna Deseo, Carol Morris, V Dixit
Dr Myrna A Deseo
No abstract provided.
Diarylheptanoid From Pleuranthodium Racemigerum With In Vitro Prostaglandin E2 Inhibitory And Cytotoxic Activity, Hans Wohlmuth, Myrna Deseo, Don Brushett, Dion Thompson, Graham Macfarlane, Lesley Stevenson, David Leach
Diarylheptanoid From Pleuranthodium Racemigerum With In Vitro Prostaglandin E2 Inhibitory And Cytotoxic Activity, Hans Wohlmuth, Myrna Deseo, Don Brushett, Dion Thompson, Graham Macfarlane, Lesley Stevenson, David Leach
Dr Myrna A Deseo
Bioactivity-guided fractionation of an ethanolic extract of the rhizome of Pleuranthodium racemigerum, a tropical Zingiberaceae species from North-eastern Australia, resulted in the isolation and structural elucidation of 1-(4″-methoxyphenyl)-7-(4′-hydroxyphenyl)-(E)-hept-2-ene (1), a new diarylheptanoid related to curcumin. Compound 1 was a fairly potent inhibitor of prostaglandin E2 production in 3T3 murine fibroblasts (IC50 ≈ 34 μM) and also displayed moderate cytotoxicity against this cell line (IC50 = 52.8 μM). The compound also demonstrated cytotoxic activity against the P388D1 murine lymphoblast cell line (IC50 = 117.0 μM) and four human cell lines: Caco-2 colonic adenocarcinoma (IC50 = 44.8 μM), PC3 prostate adenocarcinoma (IC50 …
A Comparative Study Of Seed Morphology In Relation To Desiccation Tolerance And Other Physiological Responses In 71 Eastern Australian Rainforest Species, Kim Hamilton, Catherine Offord, Peter Cuneo, Myrna Deseo
A Comparative Study Of Seed Morphology In Relation To Desiccation Tolerance And Other Physiological Responses In 71 Eastern Australian Rainforest Species, Kim Hamilton, Catherine Offord, Peter Cuneo, Myrna Deseo
Dr Myrna A Deseo
Seed characteristics were measured in 71 Eastern Australian rainforest species representing 30 families. Sensitivity to desiccation to low moisture contents (< 10%) occurred in 42% of species. We estimate, based on findings from 100 species from this present study and previously published reports, that 49% of Eastern Australian rainforest species have non-orthodox seeds. Germination level and time to 50% germination were not significantly different between desiccation sensitive (DS) and desiccation tolerant (DT) seeds. The estimation of seed desiccation sensitivity based on predictors is an important tool underpinning ex situ conservation efforts. Seed characteristics differed significantly between DS and DT seeds; …
Improvement Of Penile Erection, Sperm Count And Seminal Fructose Levels In Vivo And Nitric Oxide Release In Vitro By Ayurvedic Herbs, Mayank Thakur, Dion Thompson, Paul Connellan, Myrna Deseo, Carol Morris, V Dixit
Improvement Of Penile Erection, Sperm Count And Seminal Fructose Levels In Vivo And Nitric Oxide Release In Vitro By Ayurvedic Herbs, Mayank Thakur, Dion Thompson, Paul Connellan, Myrna Deseo, Carol Morris, V Dixit
Dr Myrna A Deseo
In the present study, the effect of four Vajikaran Rasayana herbs on penile erection, sperm count, seminal fructose content in vivo and nitric oxide (NO) release in vitro was assessed. Lyophilised aqueous extracts of Asparagus racemosus Willd. (AR), Chlorophytum borivilianum Sant. F. (CB), Curculigo orchioides Gaertn. (CO), and Dactylorhiza hatagirea (D. Don) Soo (DH) were orally administered at 100 mg/kg body weight to Wistar strain male albino rats. Penile erection index and sperm count were determined by visual observation; the seminal fructose concentration was measured spectrophotometrically using resorcinol reagent; and NO release was assessed in a mouse macrophage cell line …
Initial Events Associated With Virus Pbcv-1 Infection Of Chlorella Nc64a, Gerhard Thiel, Anna Moroni, David Dunigan, James L. Van Etten
Initial Events Associated With Virus Pbcv-1 Infection Of Chlorella Nc64a, Gerhard Thiel, Anna Moroni, David Dunigan, James L. Van Etten
David D Dunigan Ph. D.
Chlorella viruses (or chloroviruses) are very large, plaque-forming viruses. The viruses are multilayered structures containing a large double-stranded DNA genome, a lipid bilayered membrane, and an outer icosahedral capsid shell. The viruses replicate in certain isolates of the coccal green alga, Chlorella. Sequence analysis of the 330-kbp genome of Paramecium bursaria Chlorella virus 1 (PBCV-1), the prototype of the virus family Phycodnaviridae, reveals <365 protein-encoding genes and 11 tRNA genes. Products of about 40% of these genes resemble proteins of known function, including many that are unexpected for a virus. Among these is a virus-encoded protein, called Kcv, which forms …
Dna Viruses: The Really Big Ones (Giruses), James L. Van Etten, Leslie C. Lane, David Dunigan
Dna Viruses: The Really Big Ones (Giruses), James L. Van Etten, Leslie C. Lane, David Dunigan
David D Dunigan Ph. D.
Viruses with genomes greater than 300 kb and up to 1200 kb are being discovered with increasing frequency. These large viruses (often called giruses) can encode up to 900 proteins and also many tRNAs. Consequently, these viruses have more protein-encoding genes than many bacteria, and the concept of small particle/small genome that once defined viruses is no longer valid. Giruses infect bacteria and animals although most of the recently discovered ones infect protists. Thus, genome gigantism is not restricted to a specific host or phylogenetic clade. To date, most of the giruses are associated with aqueous environments. Many of these …
Chlorovirus: A Genus Of Phycodnaviridae That Infects Certain Chlorella-Like Green Algae, Ming Kang, David Dunigan, James L. Van Etten
Chlorovirus: A Genus Of Phycodnaviridae That Infects Certain Chlorella-Like Green Algae, Ming Kang, David Dunigan, James L. Van Etten
David D Dunigan Ph. D.
Taxonomy: Chlorella viruses are assigned to the family Phycodnaviridae, genus Chlorovirus, and are divided into three species: Chlorella NC64A viruses, Chlorella Pbi viruses and Hydra viridis Chlorella viruses. Chlorella viruses are large, icosahedral, plaque-forming, dsDNA viruses that infect certain unicellular, chlorella-like green algae. The type member is Paramecium bursaria chlorella virus 1 (PBCV-1).
Physical properties: Chlorella virus particles are large (molecular weight ~1 × 109 Da) and complex. The virion of PBCV-1 contains more than 100 different proteins; the major capsid protein, Vp54, comprises ~40% of the virus protein. Cryoelectron microscopy and three-dimensional image reconstruction of PBCV-1 virions …