Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Carbon (2)
- Herpesviruses; herpes simplex virus 1; HHV-1; DNA packaging terminase; pUL15; DNA packaging motor; CONGENITAL CYTOMEGALOVIRUS-INFECTION; BENZIMIDAZOLE D-RIBONUCLEOSIDES; MULTIPLE SEQUENCE ALIGNMENT; COMPOUND AIC246 LETERMOVIR; LIGAND-BINDING SITES; EPSTEIN-BARR-VIRUS; BEST-FIT MODELS; GENOME SEQUENCE; WEB SERVER; PROTEIN (2)
- Highway (2)
- Native and non-native plants (2)
- Right-of-ways (2)
-
- Sequestration (2)
- Soils (2)
- Amazonia; colonization; deforestation; ecological species invasions; land-use change; Neotropics; rain forest; RAIN-FOREST BIRDS; BRAZILIAN AMAZONIA; SPECIES RICHNESS; HOUSE SPARROWS; FUTURE; CONSERVATION; MOVEMENTS; FRAGMENTS; HABITATS; PATTERNS (1)
- Amblyomma; body condition; Cyclura cychlura; health effects; parasite; ticks; LIFE-HISTORY TRAITS; FITNESS CONSEQUENCES; NESTING-BEHAVIOR; IMMUNE-RESPONSE; BLOOD PARASITES; COMMON LIZARD; TICK; CORTICOSTERONE; POPULATION; LOAD (1)
- Andes; dispersal; Neotropical grasslands; puna; DER-EVENT SPECIATION; HISTORICAL BIOGEOGRAPHY; SPECIES LIMITS; CONTINENTAL RADIATION; GENUS ANTHUS; DISPERSAL; EVOLUTION; MODEL; VICARIANCE; SCALE (1)
- CHROMATIN-REMODELING COMPLEX; DNA-DAMAGE; NONTRANSCRIBED STRAND; NUCLEOSOME CORE; RAD16 GENES; UV DAMAGE; YEAST; H3; METHYLATION; RECOGNITION (1)
- Chewing lice; contact zones; dispersal distance; hybrid zones; pocket gophers; species replacement; POLYMORPHIC MICROSATELLITE LOCI; POCKET GOPHERS RODENTIA; COMPLEX MALLOPHAGA; THOMOMYS-BOTTAE; GENETIC DIFFERENTIATION; HYBRID ZONE; INSECTA PHTHIRAPTERA; MOLECULAR EVOLUTION; GEOMYDOECUS; TRICHODECTIDAE (1)
- Essential fish habitat; estuary; fisheries; restoration; Crassostrea virginica; ECOSYSTEM SERVICES; HABITAT RESTORATION; SUCCESS CRITERIA; RELATIVE VALUE; GALVESTON BAY; NEKTON; RESIDENT; CONSERVATION; ENHANCEMENT; BENCHMARKS (1)
- Fisetin; psoriasis; normal human epidermal keratinocyte; cell signaling; cell differentiation; proliferation; inflammatory cytokine; PBMC; CD4+T lymphocyte; 3D psoriasis-like skin disease model; DIETARY FLAVONOID FISETIN; MELANOMA CELL-GROWTH; T-CELLS; KOEBNERISIN S100A15; MAMMALIAN TARGET; DUAL INHIBITION; CANCER-CELLS; IN-VITRO; KERATINOCYTES; DISEASE (1)
- Hypersensitive response; potato virus Y; immunolocalization; ultrastructure; respiratory burst oxidase homolog D; Solanum tuberosum; PLUM POX VIRUS; NADPH OXIDASE; DISEASE RESISTANCE; MOSAIC-VIRUS; OXIDATIVE BURST; PLANT DEFENSE; TOBACCO; ACCUMULATION; PERCEPTION; INFECTION (1)
- Incubation behavior; nest success; recess movements; reproduction; Wild Turkey; LIFE-HISTORY EVOLUTION; HABITAT SELECTION; PREDATION RISK; PATTERNS; ECOLOGY; TEMPERATURE; ATTENDANCE; TOLERANCE; ADJUST; SITES (1)
- Insertion; polymorphism; evolution; subfamilies; EVOLUTION; MONKEYS; ALIGNMENT; PHYLOGENY; MARMOSET; PRIMATES; FAMILY (1)
- IscA; IscU; ferredoxin; iron-sulfur proteins; zinc toxicity; CRYSTAL-STRUCTURE; CYSTEINE DESULFURASE; SCAFFOLD PROTEIN; ASSEMBLY PROTEIN; BINDING ACTIVITY; BIOTIN SYNTHASE; OXIDASE COMPLEX; HUMAN HEALTH; ISCA; INHIBITION (1)
- Melanaphis sacchari; Sipha flava; Saccharosydne saccharivora; Perkinsiella saccharicida; Leptodictya tabida; Saccharum spp; SACCHARIVORA WESTW HOM; LEPTODICTYA-TABIDA HEMIPTERA; DIOMUS-TERMINATUS COLEOPTERA; SIPHA-FLAVA HOMOPTERA; MELANAPHIS-SACCHARI; LEPIDOPTERA CRAMBIDAE; POPULATION-DYNAMICS; DELPHACID HOMOPTERA; INSECT PESTS; APHID (1)
- Niche modeling; Phylogeography; Prionurus; Reef fish; Ultraconserved elements; REEF FISHES; ULTRACONSERVED ELEMENTS; EVOLUTIONARY HISTORY; COMPARATIVE PHYLOGEOGRAPHY; PHYLOGENETIC ANALYSIS; HAMLETS HYPOPLECTRUS; GENETIC DIVERSITY; RED-SEA; SPECIATION; BIOGEOGRAPHY (1)
- Nopp140; Repeat polymorphism; Drosophila melanogaster; NUCLEOLAR RIBONUCLEOPROTEIN-PARTICLES; TREACHER-COLLINS-SYNDROME; NUCLEAR-LOCALIZATION; PROTEIN; RNA; PHOSPHOPROTEIN; TRANSCRIPTION; HOMOLOG; BINDING; H/ACA (1)
- Ohno's hypothesis; X dosage compensation; preattachment embryos; bovine; PSEUDOAUTOSOMAL REGION; GENE-EXPRESSION; LINKED GENES; INACTIVATION; MOUSE; MAMMALS; EVOLUTION; OOCYTES; HISAT (1)
- Protein structure prediction; Hydrophobic core; External force field; MOLECULAR-DYNAMICS; AUTOMATIC METHOD; FORCE-FIELD; SIMULATION; PREDICTION; SEARCH; MODEL (1)
- RESEARCH EXPERIENCES; MARINE-BACTERIA; SAR11 STRAINS; MICROORGANISMS; DIVERSE; CULTURE; MEDIA (1)
- STRUCTURAL CLASSIFICATION; SCORING FUNCTION; SITE PREDICTION; DATABASE; KINASES; HEME; POLYPHARMACOLOGY; EVOLUTIONARY; VALIDATION; SIMILARITY (1)
- Sugarcane aphid; nitrogen; silicon; life table; host plant resistance; LIFE TABLE PARAMETERS; NITROGEN-FERTILIZATION; POPULATION-GROWTH; SUGARCANE APHID; WHEAT PLANTS; SILICON; RESISTANCE; BIOLOGY; PERFORMANCE; JACKKNIFE (1)
- Publication
Articles 1 - 24 of 24
Full-Text Articles in Life Sciences
Avian Ecological Succession In The Amazon: A Long-Term Case Study Following Experimental Deforestation, Cameron L. Rutt, Vitek Jirinec
Avian Ecological Succession In The Amazon: A Long-Term Case Study Following Experimental Deforestation, Cameron L. Rutt, Vitek Jirinec
Faculty Publications
Approximately 20% of the Brazilian Amazon has now been deforested, and the Amazon is currently experiencing the highest rates of deforestation in a decade, leading to large-scale land-use changes. Roads have consistently been implicated as drivers of ongoing Amazon deforestation and may act as corridors to facilitate species invasions. Long-term data, however, are necessary to determine how ecological succession alters avian communities following deforestation and whether established roads lead to a constant influx of new species. We used data across nearly 40 years from a large-scale deforestation experiment in the central Amazon to examine the avian colonization process in a …
Incubation Recess Behaviors Influence Nest Survival Of Wild Turkeys, Nicholas W. Bakner, Bret A. Collier, Landon R. Schofield
Incubation Recess Behaviors Influence Nest Survival Of Wild Turkeys, Nicholas W. Bakner, Bret A. Collier, Landon R. Schofield
Faculty Publications
In ground nesting upland birds, reproductive activities contribute to elevated predation risk, so females presumably use multiple strategies to ensure nest success. Identification of drivers reducing predation risk has primarily focused on evaluating vegetative conditions at nest sites, but behavioral decisions manifested through movements during incubation may be additional drivers of nest survival. However, our understanding of how movements during incubation impact nest survival is limited for most ground nesting birds. Using GPS data collected from female Eastern Wild Turkeys (n = 206), we evaluated nest survival as it relates to movement behaviors during incubation, including recess frequency, distance traveled …
Oyster Reefs In Northern Gulf Of Mexico Estuaries Harbor Diverse Fish And Decapod Crustacean Assemblages: A Meta-Synthesis, Megan K. La Peyre, Danielle Aguilar Marshall, Lindsay S. Miller
Oyster Reefs In Northern Gulf Of Mexico Estuaries Harbor Diverse Fish And Decapod Crustacean Assemblages: A Meta-Synthesis, Megan K. La Peyre, Danielle Aguilar Marshall, Lindsay S. Miller
Faculty Publications
Oyster reefs provide habitat for numerous fish and decapod crustacean species that mediate ecosystem functioning and support vibrant fisheries. Recent focus on the restoration of eastern oyster (Crassostrea virginica) reefs stems from this role as a critical ecosystem engineer. Within the shallow estuaries of the northern Gulf of Mexico (nGoM), the eastern oyster is the dominant reef building organism. This study synthesizes data on fish and decapod crustacean occupancy of oyster reefs across nGoM with the goal of providing management and restoration benchmarks, something that is currently lacking for the region. Relevant data from 23 studies were identified, representing data …
Hinge Region In Dna Packaging Terminase Pul15 Of Herpes Simplex Virus: A Potential Allosteric Target For Antiviral Drugs, Lana F. Thaljeh, J. Ainsley Rothschild, Misagh Naderi, Lyndon M. Coghill
Hinge Region In Dna Packaging Terminase Pul15 Of Herpes Simplex Virus: A Potential Allosteric Target For Antiviral Drugs, Lana F. Thaljeh, J. Ainsley Rothschild, Misagh Naderi, Lyndon M. Coghill
Faculty Publications
Approximately 80% of adults are infected with a member of the herpesviridae family. Herpesviruses establish life-long latent infections within neurons, which may reactivate into lytic infections due to stress or immune suppression. There are nine human herpesviruses (HHV) posing health concerns from benign conditions to life threatening encephalitis, including cancers associated with viral infections. The current treatment options for most HHV conditions mainly include several nucleoside and nucleotide analogs targeting viral DNA polymerase. Although these drugs help manage infections, their common mechanism of action may lead to the development of drug resistance, which is particularly devastating in immunocompromised patients. Therefore, …
Hinge Region In Dna Packaging Terminase Pul15 Of Herpes Simplex Virus: A Potential Allosteric Target For Antiviral Drugs, Lana F. Thaljeh, J. Ainsley Rothschild, Misagh Naderi, Lyndon M. Coghill, Jeremy M. Brown, Michal Brylinski
Hinge Region In Dna Packaging Terminase Pul15 Of Herpes Simplex Virus: A Potential Allosteric Target For Antiviral Drugs, Lana F. Thaljeh, J. Ainsley Rothschild, Misagh Naderi, Lyndon M. Coghill, Jeremy M. Brown, Michal Brylinski
Faculty Publications
Approximately 80% of adults are infected with a member of the herpesviridae family. Herpesviruses establish life-long latent infections within neurons, which may reactivate into lytic infections due to stress or immune suppression. There are nine human herpesviruses (HHV) posing health concerns from benign conditions to life threatening encephalitis, including cancers associated with viral infections. The current treatment options for most HHV conditions mainly include several nucleoside and nucleotide analogs targeting viral DNA polymerase. Although these drugs help manage infections, their common mechanism of action may lead to the development of drug resistance, which is particularly devastating in immunocompromised patients. Therefore, …
Fisetin, A 3,7,3 ',4 '-Tetrahydroxyflavone Inhibits The Pi3k/Akt/Mtor And Mapk Pathways And Ameliorates Psoriasis Pathology In 2d And 3d Organotypic Human Inflammatory Skin Models, Konstantin G. Kousoulas
Fisetin, A 3,7,3 ',4 '-Tetrahydroxyflavone Inhibits The Pi3k/Akt/Mtor And Mapk Pathways And Ameliorates Psoriasis Pathology In 2d And 3d Organotypic Human Inflammatory Skin Models, Konstantin G. Kousoulas
Faculty Publications
Psoriasis is a chronic immune-mediated skin disease that involves the interaction of immune and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant differentiation, inflammation, and angiogenesis. Because the available treatments for psoriasis have significant limitations, dietary products are potential natural sources of therapeutic molecules, which can repair the molecular defects associated with psoriasis and could possibly be developed for its management. Fisetin (3,7,3 ',4 '-tetrahydroxyflavone), a phytochemical naturally found in pigmented fruits and vegetables, has demonstrated proapoptotic and antioxidant effects in several malignancies. This study utilized biochemical, cellular, pharmacological, and tissue engineering tools to characterize the effects of …
Histone H4 H75e Mutation Attenuates Global Genomic And Rad26-Independent Transcription-Coupled Nucleotide Excision Repair, Shisheng Li, Kathiresan Selvam, Sheikh Arafatur Rahman
Histone H4 H75e Mutation Attenuates Global Genomic And Rad26-Independent Transcription-Coupled Nucleotide Excision Repair, Shisheng Li, Kathiresan Selvam, Sheikh Arafatur Rahman
Faculty Publications
Nucleotide excision repair (NER) consists of global genomic NER (GG-NER) and transcription coupled NER (TC-NER) subpathways. In eukaryotic cells, genomic DNA is wrapped around histone octamers (an H3-H4 tetramer and two H2A-H2B dimers) to form nucleosomes, which are well known to profoundly inhibit the access of NER proteins. Through unbiased screening of histone H4 residues in the nucleosomal LRS (loss of ribosomal DNA-silencing) domain, we identified 24 mutations that enhance or decrease UV sensitivity of Saccharomyces cerevisiae cells. The histone H4 H75E mutation, which is largely embedded in the nucleosome and interacts with histone H2B, significantly attenuates GG-NER and Rad26-independent …
Evaluation And Enhancement Of Carbon Sequestration Potential Of Existing Vegetation Along Roadsides, Vikram Kapoor, Jeffrey Hutchinson, Samer Dessouky
Evaluation And Enhancement Of Carbon Sequestration Potential Of Existing Vegetation Along Roadsides, Vikram Kapoor, Jeffrey Hutchinson, Samer Dessouky
Data
Corresponding data set for Tran-SET Project No. 18HSTSA01. Abstract of the final report is stated below for reference:
"The objectives of this study were to evaluate the vegetative composition and carbon sequestration potential of vegetation along a major roadway in Texas. Soil and vegetation were evaluated along IH-35 within Bexar County for composition and carbon content. Three 20 m transects were placed at each site and percent vegetative cover was estimated and above ground plant biomass, and soil was collected from three 0.25 m2 subplots along each transect. Plant and soil samples were analyzed for carbon content. Two non-native grasses, …
From Pampa To Puna: Biogeography And Diversification Of A Group Of Neotropical Obligate Grassland Birds (Anthus: Motacillidae), Paul Van Els
From Pampa To Puna: Biogeography And Diversification Of A Group Of Neotropical Obligate Grassland Birds (Anthus: Motacillidae), Paul Van Els
Faculty Publications
The evolution of Neotropical birds of open landscapes remains largely unstudied. We investigate the diversification and biogeography of a group of Neotropical obligate grassland birds (Anthus: Motacillidae). We use a multilocus phylogeny of 22 taxa of Anthus to test the hypothesis that these birds radiated contemporaneously with the development of grasslands in South America. We employ the R package DDD to analyze the dynamics of Anthus diversification across time in Neotropical grasslands, explicitly testing for shifts in dynamics associated with the Miocene development of grasslands, the putative Pleistocene expansion of arid lowland biomes, and Pleistocene sundering of Andean highland grasslands. …
The Nopp140 Gene In Drosophila Melanogaster Displays Length Polymorphisms In Its Large Repetitive Second Exon, Patrick J. Dimario, Sonu Shrestha Baral
The Nopp140 Gene In Drosophila Melanogaster Displays Length Polymorphisms In Its Large Repetitive Second Exon, Patrick J. Dimario, Sonu Shrestha Baral
Faculty Publications
Nopp140, often called the nucleolar and Cajal body phosphoprotein (NOLC1), is an evolutionarily conserved chaperone for the transcription and processing of rRNA during ribosome subunit assembly. Metazoan Nopp140 contains an amino terminal LisH dimerization domain and a highly conserved carboxyl domain. A large central domain consists of alternating basic and acidic motifs of low sequence complexity. Orthologous versions of Nopp140 contain variable numbers of repeating basic-acidic units. While vertebrate Nopp140 genes use multiple exons to encode the central domain, the Nopp140 gene in Drosophila uses exclusively exon 2 to encode the central domain. Here, we define three overlapping repeat sequence …
Evaluation And Enhancement Of Carbon Sequestration Potential Of Existing Vegetation Along Roadsides, Vikram Kapoor, Jeffrey Hutchinson, Samer Dessouky
Evaluation And Enhancement Of Carbon Sequestration Potential Of Existing Vegetation Along Roadsides, Vikram Kapoor, Jeffrey Hutchinson, Samer Dessouky
Publications
The objectives of this study were to evaluate the vegetative composition and carbon sequestration potential of vegetation along a major roadway in Texas. Soil and vegetation were evaluated along IH-35 within Bexar County for composition and carbon content. Three 20 m transects were placed at each site and percent vegetative cover was estimated and above ground plant biomass, and soil was collected from three 0.25 m2 subplots along each transect. Plant and soil samples were analyzed for carbon content. Two non-native grasses, bermudagrass and King Ranch bluestem, were the dominant cover at all sites accounting for > 90% coverage at several …
Temporal And Spatial Dynamics Of Competitive Parapatry In Chewing Lice, Mark S. Hafner
Temporal And Spatial Dynamics Of Competitive Parapatry In Chewing Lice, Mark S. Hafner
Faculty Publications
We synthesize observations from 1979 to 2016 of a contact zone involving two subspecies of pocket gophers (Thomomys bottae connectens and T. b. opulentus) and their respective chewing lice (Geomydoecus aurei and G. centralis) along the Rio Grande Valley in New Mexico, U.S.A., to test predictions about the dynamics of the zone. Historically, the natural flood cycle of the Rio Grande prevented contact between the two subspecies of pocket gophers. Flood control measures completed in the 1930s permitted contact, thus establishing the hybrid zone between the pocket gophers and the contact zone between their lice (without hybridization). Since that time, …
The Respiratory Burst Oxidase Homolog D (Rbohd) Cell And Tissue Distribution In Potato-Potato Virus Y (Pvyntn) Hypersensitive And Susceptible Reactions, Rodrigo A. Valverde
The Respiratory Burst Oxidase Homolog D (Rbohd) Cell And Tissue Distribution In Potato-Potato Virus Y (Pvyntn) Hypersensitive And Susceptible Reactions, Rodrigo A. Valverde
Faculty Publications
The respiratory burst oxidase homolog D (RbohD) acts as a central driving force of reactive oxygen species signaling in plant cells by integrating many different signal transduction pathways in plants, including incompatible interactions with pathogens. This study demonstrated the localization and distribution of RbohD in two types of potato-potato virus Y (PVY) interactions: Compatible and incompatible (resistant). The results indicated a statistically significant induction of the RbohD antigen signal in both interaction types. In the hypersensitive response (resistant reaction) of potato with a high level of resistance to the potato tuber necrotic strain of PVY (PVYNTN), RbohD localization followed by …
Zinc Toxicity And Iron-Sulfur Cluster Biogenesis In Escherichia Coli, Huangen Ding
Zinc Toxicity And Iron-Sulfur Cluster Biogenesis In Escherichia Coli, Huangen Ding
Faculty Publications
While zinc is an essential trace metal in biology, excess zinc is toxic to organisms. Previous studies have shown that zinc toxicity is associated with disruption of the (4Fe-4S] clusters in various dehydratases in Escherichia coli. Here, we report that the intracellular zinc overload in E. coli cells inhibits iron-sulfur cluster biogenesis without affecting the preassembled iron-sulfur clusters in proteins. Among the housekeeping iron-sulfur cluster assembly proteins encoded by the gene cluster iscSUA-hscBA-fdx-iscX in E. coli cells, the scaffold IscU, the iron chaperone IscA, and ferredoxin have strong zinc binding activity in cells, suggesting that intracellular zinc overload inhibits iron-sulfur …
Hemipteran Pests Of Sugarcane In North America, Blake E. Wilson
Hemipteran Pests Of Sugarcane In North America, Blake E. Wilson
Faculty Publications
ing-sucking herbivores (Insecta: Hemiptera) represent one of the greatest threats to agricultural production worldwide. Hemipteran pests directly injure plants as well as vector disease-causing plant pathogens. Production of sugarcane (Saccharum spp.) in North America is impacted by a complex of Hemiptera including the sugarcane aphid, Melanaphis sacchari Zehntner (Aphididae); yellow sugarcane aphid, Sipha flava (Forbes) (Aphididae); West Indian canefly, Saccharosydne saccharivora (Westwood) (Delphacidae); sugarcane delphacid, Perkinsiella saccharicida Kirkaldy (Delphacidae); and sugarcane lace bug, Leptodictya tabida (Herric-Schaeffer) (Tingidae). None of these pests is consistently damaging to large amounts of sugarcane acreage, but regional outbreaks are common. The biology, ecology, and pest …
The Cure For Cultivating Fastidious Microbes, William Wischusen, Arundhati Bakshi, Austen T. Webber, Lorelei E. Patrick
The Cure For Cultivating Fastidious Microbes, William Wischusen, Arundhati Bakshi, Austen T. Webber, Lorelei E. Patrick
Faculty Publications
Course-Based Undergraduate Research Experiences (CUREs) expand the scientific educational benefits of research to large groups of students in a course setting. As part of an ongoing effort to integrate CUREs into first-year biology labs, we developed a microbiology CURE (mCURE) that uses a modified dilution-to-extinction high throughput culturing protocol for isolating abundant yet fastidious aquatic bacterioplankton during one semester. Students learn common molecular biology techniques like nucleic acid extraction, PCR, and molecular characterization; read and evaluate scientific literature; and receive training in scientific communication through written and oral exercises that incorporate social media elements. In the first three semesters, the …
Influence Of Sorghum Cultivar, Phenological Stage, And Fertilization On Development And Reproduction Of Melanaphis Sacchari (Hemiptera: Aphididae), Blake E. Wilson, Jeffrey Davis, Thomas Reagan, Luna Lama
Influence Of Sorghum Cultivar, Phenological Stage, And Fertilization On Development And Reproduction Of Melanaphis Sacchari (Hemiptera: Aphididae), Blake E. Wilson, Jeffrey Davis, Thomas Reagan, Luna Lama
Faculty Publications
The sugarcane aphid, Melanaphis sacchari (Zehntner) (Hemiptera: Aphididae), is an invasive pest of grain sorghum, Sorghum bicolor (L) Moench (Poaceae). Since its first outbreak in sorghum in 2013, severe infestations have spread throughout the southern USA, causing major economic losses. Whereas insecticide applications can mitigate some of the pest's impacts, a sustainable ecology-based management program is needed to reduce reliance on chemical control. Two greenhouse assays examined the influence of selected host plant characteristics on M. sacchari life table parameters. We studied the effects of silicon (rates equivalent to 0 and 3,360 kg silicon per ha) and nitrogen (rates equivalent …
Amplification Dynamics Of Platy-1 Retrotransposons In The Cebidae Platyrrhine Lineage, Mark A. Batzer, Jessica M. Storer, Jackson R. Mierl, Sarah A. Brantley
Amplification Dynamics Of Platy-1 Retrotransposons In The Cebidae Platyrrhine Lineage, Mark A. Batzer, Jessica M. Storer, Jackson R. Mierl, Sarah A. Brantley
Faculty Publications
Platy-1 elements are Platyrrhine-specific, short interspersed elements originally discovered in the Callithrix jacchus (common marmoset) genome. To date, only the marmoset genome has been analyzed for Platy-1 repeat content. Here, we report full-length Platy-1 insertions in other New World monkey (NWM) genomes (Saimiri boliviensis, squirrel monkey; Cebus imitator, capuchin monkey; and Aotus nancymaae, owl monkey) and analyze the amplification dynamics of lineage-specific Platy-1 insertions. A relatively small number of full-length and lineage-specific Platy-1 elements were found in the squirrel, capuchin, and owl monkey genomes compared with the marmoset genome. In addition, only a few older Platy-1 subfamilies were recovered in …
Genomic, Ecological, And Morphological Approaches To Investigating Species Limits: A Case Study In Modern Taxonomy From Tropical Eastern Pacific Surgeonfishes, Prosanta Chakrabarty
Genomic, Ecological, And Morphological Approaches To Investigating Species Limits: A Case Study In Modern Taxonomy From Tropical Eastern Pacific Surgeonfishes, Prosanta Chakrabarty
Faculty Publications
A wide variety of species are distinguished by slight color variations. However, molecular analyses have repeatedly demonstrated that coloration does not always correspond to distinct evolutionary histories between closely related groups, suggesting that this trait is labile and can be misleading for species identification. In the present study, we analyze the evolutionary history of sister species of Prionurus surgeonfishes in the Tropical Eastern Pacific (TEP), which are distinguished by the presence or absence of dark spots on their body. We examined the species limits in this system using comparative specimen-based approaches, a mitochondrial gene (COI), more than 800 nuclear loci …
The Aqueous Environment As An Active Participant In The Protein Folding Process, Michal Brylinski
The Aqueous Environment As An Active Participant In The Protein Folding Process, Michal Brylinski
Faculty Publications
Existing computational models applied in the protein structure prediction process do not sufficiently account for the presence of the aqueous solvent. The solvent is usually represented by a predetermined number of H2O molecules in the bounding box which contains the target chain. The fuzzy oil drop (FOD) model, presented in this paper, follows an alternative approach, with the solvent assuming the form of a continuous external hydrophobic force field, with a Gaussian distribution. The effect of this force field is to guide hydrophobic residues towards the center of the protein body, while promoting exposure of hydrophilic residues on its surface. …
Vegetation Phenology And Nest Survival: Diagnosing Heterogeneous Effects Through Time, Kevin M. Ringelman
Vegetation Phenology And Nest Survival: Diagnosing Heterogeneous Effects Through Time, Kevin M. Ringelman
Faculty Publications
bias; duck; grassland; mallard; prairie; Robel; waterfowl; WATERFOWL PRODUCTION; HABITAT SELECTION; ARTIFICIAL NESTS; MOTTLED DUCKS; WINTER-WHEAT; SUCCESS; NORTH; PREDATION; CONCEALMENT; FIELDS
Deepdrug3d: Classification Of Ligand-Binding Pockets In Proteins With A Convolutional Neural Network, Michal Brylinski, Limeng Pu, Rajiv Gandhi Govindaraj, Jeffrey Mitchell Lemoine
Deepdrug3d: Classification Of Ligand-Binding Pockets In Proteins With A Convolutional Neural Network, Michal Brylinski, Limeng Pu, Rajiv Gandhi Govindaraj, Jeffrey Mitchell Lemoine
Faculty Publications
Comprehensive characterization of ligand-binding sites is invaluable to infer molecular functions of hypothetical proteins, trace evolutionary relationships between proteins, engineer enzymes to achieve a desired substrate specificity, and develop drugs with improved selectivity profiles. These research efforts pose significant challenges owing to the fact that similar pockets are commonly observed across different folds, leading to the high degree of promiscuity of ligand-protein interactions at the system-level. On that account, novel algorithms to accurately classify binding sites are needed. Deep learning is attracting a significant attention due to its successful applications in a wide range of disciplines. In this communication, we …
Host Sex, Size, And Hemoparasite Infection Influence The Effects Of Ectoparasitic Burdens On Free-Ranging Iguanas, Christine Lattin
Host Sex, Size, And Hemoparasite Infection Influence The Effects Of Ectoparasitic Burdens On Free-Ranging Iguanas, Christine Lattin
Faculty Publications
Investigations focusing on host-ectoparasite interactions in animals have revealed asymptomatic to severe health and fitness consequences suggesting that species mobilize different interspecific response mechanisms. Fewer studies, however, have examined intraspecific responses to ectoparasitic burdens. In this study, we analyzed host health and fitness responses to increasing ectoparasite burdens along with the presence/absence of hemoparasites of free-ranging insular rock iguanas (Cyclura cychlura) in The Bahamas. Using hematology, plasma biochemistry, as well as body condition and growth rate comparisons, we failed to find significant associations of tick burdens with annual growth rate, corticosterone, packed cell volume, total white blood cell, and heterophil, …
Dosage Compensation Of The X Chromosomes In Bovine Germline, Early Embryos, And Somatic Tissues, Zongliang Jiang
Dosage Compensation Of The X Chromosomes In Bovine Germline, Early Embryos, And Somatic Tissues, Zongliang Jiang
Faculty Publications
Dosage compensation of the mammalian X chromosome (X) was proposed by Susumu Ohno as a mechanism wherein the inactivation of one X in females would lead to doubling the expression of the other. This would resolve the dosage imbalance between eutherian females (XX) versus male (XY) and between a single active X versus autosome pairs (A). Expression ratio of X- and A-linked genes has been relatively well studied in humans and mice, despite controversial results over the existence of upregulation of X-linked genes. Here we report the first comprehensive test of Ohno's hypothesis in bovine preattachment embryos, germline, and somatic …