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Augustana College

Meiothermus ruber Genome Analysis Project

Series

2017

Mrub_0981

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Full-Text Articles in Life Sciences

Annotation Of Genes Involved With Biosynthetic Production Of Peptidoglycan Within Meiothermus Ruber Involving Supposed Orthologous Genes: Mrub_0981 And B1069, Mrub_1162 And B063, Mrub_1999 And B0084., Marckus Simmons, Dr. Lori Scott Jan 2017

Annotation Of Genes Involved With Biosynthetic Production Of Peptidoglycan Within Meiothermus Ruber Involving Supposed Orthologous Genes: Mrub_0981 And B1069, Mrub_1162 And B063, Mrub_1999 And B0084., Marckus Simmons, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

Using bioinformatics tools, the genes within Meiothermus ruber that are involved with peptidoglycan production were annotated. We predict that Mrub_0981 encodes the enzyme Lipid II Flippase (DNA coordinates970078…971580 on the reverse strand), which is the 9th step of the Peptidoglycan biosynthesis pathway (KEGG map number 00550) It catalyzes the conversion of Meso-2,6-diaminopimelate to Peptidoglycan. The E. coli K12 MG1655 ortholog is predicted to be b1069, which has the gene identifier mviN. We also predict that Mrub_1162 encodes the enzyme Penicillin binding protein II (DNA coordinates 1176079…1177836 on the reverse strand), which is the 12th step of the Peptidoglycan biosynthesis …