Life Sciences Commons^™

Spatial Analysis Of Factors Influencing Long-Term Stress In The Grizzly Bear (Ursus Arctos) Population Of Alberta, Canada, Mathieu Bourbonnais, Trisalyn Nelson, Mark Cattet, Chris T. Darimont, Gordon Stenhouse

Physiology Collection

Non-invasive measures for assessing long-term stress in free ranging mammals are an increasingly important approach for understanding physiological responses to landscape conditions. Using a spatially and temporally expansive dataset of hair cortisol concentrations (HCC) generated from a threatened grizzly bear (Ursus arctos) population in Alberta, Canada, we quantified how variables representing habitat conditions and anthropogenic disturbance impact long-term stress in grizzly bears. We characterized spatial variability in male and female HCC point data using kernel density estimation and quantified variable influence on spatial patterns of male and female HCC stress surfaces using random forests. Separate models were developed for regions …

Longevity And Mortality Of Owned Dogs In England, D. G. O'Neill, D. B. Church, P. D. Mcgreevy, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity. Epidemiological research using electronic patient records (EPRs) collected from primary veterinary practices overcomes many inherent limitations of referral clinic, owner questionnaire and pet insurance data. Clinical health data from 102,609 owned dogs attending first opinion veterinary practices (n = 86) in central and southeast England were analysed, focusing on 5095 confirmed deaths.

Of deceased dogs with information available, 3961 (77.9%) were purebred, 2386 (47.0%) were female, 2528 (49.8%) were neutered and 1105 (21.7%) were insured. The overall median longevity was 12.0 years …

Stress And Reproductive Hormones In Grizzly Bears Reflect Nutritional Benefits And Social Consequences Of A Salmon Foraging Niche, Heather M. Bryan, Chris T. Darimont, Paul C. Paquet, Katherine E. Wynne-Edwards, Judit E. G. Smits

Physiology Collection

Physiological indicators of social and nutritional stress can provide insight into the responses of species to changes in food availability. In coastal British Columbia, Canada, grizzly bears evolved with spawning salmon as an abundant but spatially and temporally constrained food source. Recent and dramatic declines in salmon might have negative consequences on bear health and ultimately fitness. To examine broadly the chronic endocrine effects of a salmon niche, we compared cortisol, progesterone, and testosterone levels in hair from salmon-eating bears from coastal BC (n = 75) with the levels in a reference population from interior BC lacking access to salmon …

A Free-Ranging, Feral Mare Equus Caballus Affords Similar Maternal Care To Her Genetic And Adopted Offspring, Cassandra M.V. Nuñez, James S. Adelman, Daniel I. Rubenstein

Cassandra M.V. Nuñez

Adoption of nongenetic offspring occurs in a variety of species but is rare in equids. We report a case of adoption by a free-ranging, feral mare Equus caballus and compare the maternal care received by her genetic offspring (born 1995) to that of her adopted offspring (born 1996) for the first 30 weeks of development. We compare five measures of care: (1) total time spent suckling, (2) mare aggression during suckling, (3) number of mare-terminated suckling bouts, (4) contact maintenance, and (5) mare-foal distance. For most behaviors, we detected no difference in the mare’s treatment of the two foals; however, …

Welcome To The Journal Of Evolution And Health, Aaron Blaisdell, Paul Jaminet, David C. Pendergrass

Aaron P Blaisdell

Welcome to the first issue of the Journal of Evolution and Health! The Journal of Evolution and Health is the peer-reviewed, open-access journal of the Ancestral Health Society, a community of scientists, healthcare professionals, and laypersons who collaborate to understand health challenges from an evolutionary perspective.

Evaluación De Un Protocolo De Inseminación Artificial A Tiempo Fijo Con Variaciones En Los Días De Aplicada La Dosis De Prostaglandina En Novillas Brahman Puras Y Cruzadas, Jorge Andrés Prada Torres, Jefferson Abdelo Castro Cruz, Ariosto Ardila Silva, Liliana Chacón Jaramillo

Revista Ciencia Animal

Los eventos reproductivos se encuentran influenciados por factores como la edad, el peso, la raza y el medio ambiente. El objetivo de la presente investigación fue determinar diferencias en la respuesta de la aplicación de un protocolo de inseminación artificial a tiempo fijo (IATF) en novillas puras y cruzadas, con variaciones en los días de aplicación de la dosis de prostaglandina (PGF2α), sobre los porcentajes de preñez. El estudio se desarrolló en una finca del municipio de Barranca de Upía, Meta, Colombia. Se estableció un protocolo hormonal para realizar la IATF y las novillas se dividieron en dos grupos: el …

Small Molecule Antagonists Of Melanopsin-Mediated Phototransduction, Kenneth A. Jones, Megumi Hatori, Ludovic S. Mure, Jayne R. Bramley, Roman Artymyshyn, Sang-Phyo Hong, Mohammad Marzabadi, Huailing Zhong, Jeffrey Sprouse, Quansheng Zhu, Andrew T. E. Hartwick, Patricia J. Sollars, Gary E. Pickard, Satchidananda Panda

School of Veterinary and Biomedical Sciences: Faculty Publications

Melanopsin, expressed in a subset of retinal ganglion cells, mediates behavioral adaptation to ambient light and other non-image forming photic responses. This has raised the possibility that pharmacological manipulation of melanopsin can modulate several CNS responses including photophobia, sleep, circadian rhythms and neuroendocrine function. Here we describe the identification of a potent synthetic melanopsin antagonist with in vivo activity. Novel sulfonamide compounds inhibiting melanopsin (opsinamides) compete with retinal binding to melanopsin and inhibit its function without affecting rod/cone mediated responses. In vivo administration of opsinamides to mice specifically and reversibly modified melanopsin-dependent light responses including the pupillary light reflex and …

Growing South Dakota (Fall 2013), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Crop Watchers: Plant Science Department Research Efforts Strive To Enhance Farming Practices
[Page] 5 Profiles In Leadership: David Wright; Collegiate Leadership Matters
[Page] 6 Fall Collegiate News
[Page] 8 Opportunities To Explore: College’s Summer Camps Help Spark Career Interests
[Page] 10 Collaborative Campaign: Sales Of Cull Cows Helping Fund New SDSU Cow-Calf Facility
[Page] 12 Notable
[Page] 13 A Message From The SDSU Foundation

The Genome And Developmental Transcriptome Of The Strongylid Nematode Haemonchus Contortus, Erich M. Schwarz, Pasi K. Korhonen, Bronwyn E. Campbell, Neil D. Young, Aaron R. Jex, Abdul Jabbar, Ross S. Hall, Alinda Mondal, Adina C. Howe, Jason Pell, Andreas Hofmann, Peter R. Boag, Xing-Quan Zhu, T. Ryan Gregory, Alex Loukas, Brian A. Williams, Igor Antoshechkin, C. Titus Brown, Paul W. Sternberg, Robin B. Gasser

Adina Howe

Background The barber's pole worm, Haemonchus contortus, is one of the most economically important parasites of small ruminants worldwide. Although this parasite can be controlled using anthelmintic drugs, resistance against most drugs in common use has become a widespread problem. We provide a draft of the genome and the transcriptomes of all key developmental stages of H. contortus to support biological and biotechnological research areas of this and related parasites. Results The draft genome of H. contortus is 320 Mb in size and encodes 23,610 protein-coding genes. On a fundamental level, we elucidate transcriptional alterations taking place throughout the life …

Osmotic Stress, Not Aldose Reductase Activity, Directly Induces Growth Factors And Mapk Signaling Changes During Sugar Cataract Formation, Peng Zhang, Kuiyi Xing, James Randazzo, Karen Blessing, Marjorie F. Lou, Peter Kador

School of Veterinary and Biomedical Sciences: Faculty Publications

In sugar cataract formation in rats, aldose reductase (AR) actitvity is not only linked to lenticular sorbitol (diabetic) or galactitol (galactosemic) formation but also to signal transduction changes, cytotoxic signals and activation of apoptosis. Using both in vitro and in vivo techniques, the interrelationship between AR activity, polyol (sorbitol and galactitol) formation, osmotic stress, growth factor induction, and cell signaling changes have been investigated. For in vitro studies, lenses from Sprague Dawley rats were cultured for up to 48 hrs in TC-199-bicarbonate media containing either 30 mM fructose (control), or 30 mM glucose or galctose with/without the aldose reductase inhibitors …

Kisspeptin Receptor Agonist (Ftm080) Increased Plasma Concentrations Of Luteinizing Hormone In Anestrous Ewes, Brian K. Whitlock, Kelly A. Chameroy, Rebecca R. Payton, Shinya Oishi, Nobutaka Fujii, Joseph A. Daniel

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin (KP) and the KP receptor (Kiss1r) are integral to central regulation of the gonadotropic-axis. The demonstration that intravenous infusion of KP can stimulate gonadotropin secretion and ovulation in seasonally anestrous female sheep offers a means of manipulating the reproductive axis. However, KP may be of limited clinical use because of the short circulating half-life. Kiss1r agonists with increased half-life and similar efficacy to KP in vitro potentially may provide beneficial applications in breeding management of many species. However, many of these agonists have not been tested in vivo. This study was designed to test and compare the effects of …

Heterogeneous Nuclear Ribonucleoprotein K Supports Vesicular Stomatitis Virus Replication By Regulating Cell Survival And Cellular Gene Expression, Phat X. Dinh, Anshuman Das, Rodrigo Franco, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

The heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a member of the family of hnRNPs and was recently shown in a genome-wide small interfering RNA (siRNA) screen to support vesicular stomatitis virus (VSV) growth. To decipher the role of hnRNP K in VSV infection, we conducted studies which suggest that the protein is required for VSV spreading. Virus binding to cells, entry, and nucleocapsid uncoating steps were not adversely affected in the absence of hnRNP K, whereas viral genome transcription and replication were reduced slightly. These results indicate that hnRNP K is likely involved in virus assembly and/or release from …

Volume 10, Number 1 (Spring/Summer 2013), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

• The four pillars of the Institute of Agriculture
• Alumna forges partnership amid Waldo Canyon fire
• Fishery biologists revive a river

Effect Of Meloxicam On Gain And Inflammatory Response Of Calves Castrated By Banding Post-Weaning, Brian K. Whitlock, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves, and painful procedures are increasingly becoming a public concern. The objective of this study was to determine the effects of castration (by banding) with or without administration of meloxicam, a non-steroid anti-inflammatory, on performance and inflammatory response in weaned beef calves. Forty-eight (weaned) beef calves [10.0±0.2 mo old; 304±6 kg BW] were blocked by age, BW, wither height, scrotal circumference, and source, then randomly assigned to 1 of 3 treatments (n=16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding with …

Effect Of Meloxicam On Gain And Behavior Of Calves Castrated By Banding Pre-Weaning, Joseph A. Daniel, Peter D. Krawczel, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

The objective was to determine if oral meloxicam (M; a non-steroid anti-inflammatory) administered at castration of pre-weaning calves affected ADG or behavior. Prior to castration (14 d), Angus bulls were assigned to bull (BULL; n = 7; age 106 ± 6 d; BW = 174.2 ±7.7 kg; scrotal circumference 17.7 ± 0.4 cm), castrated (BAN; n = 12; age = 105 ± 5 d; BW = 144.5 ± 7.6 kg; scrotal circumference = 16 ± 0.4 cm) or castrated with meloxicam (BAN+M; n = 13; age = 121 ± 6 d; BW = 145.8 ± 6 kg; scrotal circumference = …

Meloxicam Mediates Short-Term Behavioral Changes Of Castrated Calves, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves and painful procedures are increasingly a public concern. Therefore, practical pain mitigation is critical. The objective was to determine the effects of castration (by banding) with or without administration of NSAID, meloxicam, on the behavior of weaned beef calves. Forty-eight (56 d post-weaning) beef calves [10.0 ± 0.2 (mean ± SE) mo old; 304 ± 6 kg BW] were blocked by multiple factors then randomly assigned to 3 treatments (n = 16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding …

Growing South Dakota (Summer 2013), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Fish, Field & Forest: Natural Resource Management Research Covers the Gamut
[Page] 5 Profiles In Leadership: David Willis; Combined Department Creates Interdisciplinary Opportunities
[Page] 6 Research On the Range: Cottonwood Field Station Has Provided Research Data for 106 Years
[Page] 8 Prairie Oasis: Natural Diversity Showcased at Oak Lake Field Station
[Page] 9 Special Section: Investigating in Agriculture & Biological Sciences at SDSU: An Update On the College of Ag’s Enhanced Facilities and Continuing Efforts Important to Helping Address Future Agricultural Challenges and Opportunities.[Page] 13 South Dakota 4-H Update: Skill-a-thons, New Exhibit Hall Planned
[Page] 14 After The …

The 23rd Annual Research Conference Abstract Booklet, Mulu Aderie Alemu, Nikki Lynn Rogers

University of Gondar Research Conferences

Staff members, postgraduate and senior undergraduate students of the University, invited guests and speakers participated in the conference. The annual conference of the University is meant to share experiences in research activities among juniors and seniors, staff and students, and invited guests. It is also meant to motivate students and young faculty to engage in research and also to initiate and strengthen interdisciplinary collaborations. The findings of the studies and the resulting recommendations are expected to be used in solving the diverse societal problems we have been facing.

Research activities at the University of Gondar are primarily aimed at solving …

House Finch Populations Differ In Early Inflammatory Signaling And Pathogen Tolerance At The Peak Of Mycoplasma Gallisepticum Infection, James S. Adelman, Laila Kirkpatrick, Jessica L. Grodio, Dana M. Hawley

James S. Adelman

Host individuals and populations often vary in their responses to infection, with direct consequences for pathogen spread and evolution. While considerable work has focused on the mechanisms underlying differences in resistance—the ability to kill pathogens— we know little about the mechanisms underlying tolerance— the ability to minimize fitness losses per unit pathogen. Here, we examine patterns and mechanisms of tolerance between two populations of house finches (Haemorhous [formerly Carpodacus] mexicanus) with different histories with the bacterial pathogen Mycoplasma gallisepticum (MG). After infection in a common environment, we assessed two metrics of pathology, mass loss and eye lesion severity, as proxies …

Assessment Of Introduction Pathway For Novel Avian Influenza Virus Into North America By Wild Birds From Eurasia, Ryan S. Miller, Steven J. Sweeney, Judy E. Akkina, Emi K. Saito

Other Publications in Zoonotics and Wildlife Disease

A critical question surrounding emergence of novel strains of avian influenza viruses (AIV) is the ability for wild migratory birds to translocate a complete (unreassorted whole genome) AIV intercontinentally. Virus translocation via migratory birds is suspected in outbreaks of highly pathogenic strain A(H5N1) in Asia, Africa, and Europe. As a result, the potential intercontinental translocation of newly emerging AIV (e.g. A(H7N9) from Eurasia to North America via migratory movements of birds) remains a concern. An estimated 1.48 to 2.91 million aquatic birds, principally Anseriformes (ducks, geese, and swans) and Charadriiformes (gulls, terns, and shorebirds) move annually between Eurasia and North …

Influence Of Horn Flies And Breed Type On Milk Production, Calf Production Traits, Pasture Behavior, And Temperament Measurements In Beef Cattle, Angela Rene Mays

Graduate Theses and Dissertations

An experiment conducted in El Reno, Oklahoma during the fly season (May - September/October) evaluated the effects of horn flies on milk production, calf performance, and pasture behavior and temperament measurements of beef cow calf pairs. Cows (n = 53) sired by Bonsmara (BONS; n = 7), Brangus (BRAN; n = 13), Charolais (CHAR; n = 8), Gelbvieh (GELV; n = 5), Hereford (HERF; n = 12), and Romosinuano (ROMO; n = 8) from Brangus dams and their Angus sired calves (n = 51) were used in the study. Horn fly counts (HFC) and milk yield and quality estimates were …

Genetic Analysis Of The Promoter Region Of The Serotonin Receptor 5ht2b And Its Contribution To Pulmonary Hypertension Syndrome In Broiler-Type Chickens, Khaloud Awada Alzahrani

Graduate Theses and Dissertations

Pulmonary Arterial Hypertension (PAH) is a sever disorder characterized by high pulmonary artery pressure and pulmonary vascular resistance along with specific histological changes. Idiopathic PAH is a human disease of unknown origin that showed common characteristics to PHS/ascites in chicken. PHS/ascites is a condition found in broilers causing right ventricular hypertrophy, valvular insufficiency, increased venous pressure, variable liver changes, accumulation of fluids in the abdominal cavity, and finally lung and heart failure. Currently, there is no acceptable animal model for human PAH. Our group has been validating the chicken as the medical animal model for human PAH, thus we have …

Distribution, Prevalence, And Genetic Analysis Of Panulirus Argus Virus 1 (Pav1) From The Caribbean Sea, Jessica Moss, Donald C. Behringer Jr., Jeffrey D. Shields, Antonio Baeza, Alfonso Aguilar-Perera, Phillippe G. Bush, Clement Dromer, Alejandro Herrera-Moreno, Lester Gittens, Thomas R. Matthews, Michael R. Mccord, Michelle T. Schärer, Lionel Reynal, Nathanial Truelove, Mark J. Butler Iv

Biological Sciences Faculty Publications

The pathogenic virus Panulirus argus virus 1 (PaV1) was first discovered in Caribbean spiny lobsters Panulirus argus from the Florida Keys (USA) in 1999 and has since been reported in Belize, Mexico, and Cuba; its distribution in the wider Caribbean is unknown. We collected tissue samples from adult spiny lobsters from 30 locations in 14 countries bordering the Caribbean Sea and used molecular diagnostics to assay for the presence of PaV1. PaV1 occurred primarily in the northern areas of the Caribbean, where its prevalence was highest. The virus was not found in lobsters from the southeastern Caribbean, and its prevalence …

Maternal Obesity Alters Fetal Development Due To Impaired Placental Function And Has Lasting Effects On Adult Offspring, Kristin Ann Norwood

Department of Animal Science: Dissertations, Theses, and Student Research

Obesity is an epidemic in many developed nations and maternal obesity can result in developmental alterations in offspring that have long-lasting effects. Two experiments were conducted to determine the impact of maternal obesity on placental development and early embryonic growth and muscle development. Experiment one utilized obese Lethal Yellow (LY) and normal weight C57BL/6 (B6) dams to assess how maternal obesity alters skeletal muscle development in mid-gestational embryos. Embryos from LY dams exhibited decreased embryo and placental weights as well as an increase in the myogenic marker desmin. Furthermore, the adipogenic marker PPARG expression was predominately localized to the neural …

Natural Dog Training Provides New Ways To Understand And Manage Stresses Of Canine Assistance Work, Jean Marie Thompson, Kevin Behan

International Veterinary Social Work Summit

Limiting dis-stress experienced by assisted therapy, crisis response, and combat comfort dogs is a concern of handlers, organizations, and researchers. Dogs communicate feelings via body language especially muzzle expressions and physical behaviors that people and other animals recognize. Projection of dis-stress by dogs negatively impacts therapeutic interactions, distracting and detracting from beneficial flow of feelings. Dog welfare is risked. Behan's Natural Dog Training ("NDT") presents an alternative paradigm for understanding dog dis-stress. NDT is an energy flow model that is different from but compatible with positive reinforcement techniques and attuned to Adrian Bejan's constructal law of nature, a physics principle. …

The Link, One Health, And Social Capital: A New Strategy For Empathy Education And Social Work, Phil Arkow

International Veterinary Social Work Summit

For 150 years, animal welfare and veterinary advocates have promoted a doctrine that animal welfare will be enhanced by teaching children kindness to animals and responsible animal husbandry practices. However, these efforts have been stymied by societal and professional perceptions that “animal” causes are less worthy than “human” services. Ten significant challenges have made it difficult, if not impossible, to gain access to educators’ curricula and social work training. In a society that continues to place humans’ interests above animals’, it is time to try a new approach that focuses on the human benefits of animal welfare. In particular, a …

Compassion Fatigue Or Ethics Exhaustion?, Sonnya Dennis

International Veterinary Social Work Summit

Compassion Fatigue or Ethics Exhaustion?

In veterinary practice, the diagnosis is critical for proper treatment. Different diseases can cause the same symptoms, and while palliative treatment is sometimes necessary, ideally we want prevention or cure. In this talk, I will speak from the experiential perspective of companion animal general practice about the very real and common problem of compassion fatigue, and why it is different from, and can mask, what I call Ethics Exhaustion. In brief, I define Ethics Exhaustion as the feeling of being powerless to even try to do what you think that you ethically should do, because …

Cruelty Intervention Advocacy, A New Approach To Animal Hoarding Interventions, Allison Cardona

International Veterinary Social Work Summit

Animal hoarding affects thousands of animals and people across the United States. Conservative estimates place the number of new cases at two to three thousand per year, though no centralized database exists, so the full scope of the problem is unknown. Unlike intentional, single acts of cruelty, animal hoarding impacts a large number of animals over a prolonged period of time. Any type of animal can be hoarded, though the majority of hoarding situations involve cats and dogs, with numbers ranging from a few dozen to several hundred and even thousands of animals living in a single location. Accumulation of …

Canines And Childhood Cancer: The Effects Of Animal-Assisted Therapy For Patients, Families And Therapy Dogs, Molly Jenkins Msw, Amy Mccullough Ma, Ashleigh Ruehrdanz Ba, Kevin Morris Ph.D.

International Veterinary Social Work Summit

PLEASE USE THE PDF (available from the "download" link) TO FOLLOW ALONG WITH THE VIDEO

For many people, animals take center stage in their daily lives, offering companionship, comfort, joy and for some, even kinship. Increasingly, greater attention has been given to the roles that animals can play in supporting the health and emotional well-being of people in need, specifically through the use of animal-assisted therapy (AAT). However, while the field of human-animal interaction (HAI) research has expanded enormously in recent years, it is still unclear whether the incorporation of animals into clinical settings is effective from a scientific standpoint. …

Growing South Dakota (Spring 2013), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Food Focus: SDSU Leading National Effort To Promote Healthy Food Choices
[Page] 3 In Stores Now: “Pick It, Try It, Like It” Fruit & Vegetable Campaign
[Page] 4 Coaching Food Entrepreneurs: SDSU Extension Outreach Includes Entrepreneur Workshops
[Page] 5 From South Dakota to South America: College of Agriculture & Biological Science Students Experience Argentine Agriculture
[Page] 6 Spring College News
[Page] 8 Showcasing Ag’s Evolution: SDSU’s Ag Museum Is More Than Just Tractors [Page] 10 Mastering Marketing: Students Host Bull Sale Through Unique Class [Page] 11 Following Pheasants: SDSU Researchers Analyze Nesting Needs
[Page] 12 Faculty Highlights
[Page] …