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Full-Text Articles in Life Sciences
Prospective Associations Of Homocysteine, Executive Function, And Depressive Symptoms, Peter J. Dearborn
Prospective Associations Of Homocysteine, Executive Function, And Depressive Symptoms, Peter J. Dearborn
Electronic Theses and Dissertations
Associations of cardiovascular risk factors, cognitive performance, and depressive symptoms have been well established. However, the directionality of these associations as well as the specificity of these associations with respect to executive function are less clear. Additionally few studies have determined whether genetic risk factors, such as apolipoprotein-E4 (APOE-E4) genotype, and age moderate the associations of cardiovascular risk factors such as homocysteine with changes in depressive symptoms and how these associations may be mediated by cognitive performance. The primary aim of this study was to analyze the bidirectional associations of a full range of cognitive domains and symptoms of depression …
Developing A Collaborative Research Program To Evaluate Fine-Scale Groundfish Dynamics In Eastern Maine, Mattie Rodrigue
Developing A Collaborative Research Program To Evaluate Fine-Scale Groundfish Dynamics In Eastern Maine, Mattie Rodrigue
Electronic Theses and Dissertations
Fisheries science conducted and used for management strategies in the Gulf of Maine (GOM) is conducted at broad spatial and temporal scales. There is a tendency for fisheries-independent monitoring programs, which play a critical role in fisheries assessment and management, to miss fine-scale dynamics, especially given the complex hydrographic structures characterizing the GOM. In New England, fishermen participating in a heterogeneous groundfish fishery within the GOM may have varied perceptions of fish abundance or distribution depending on the scale at which they participate in the fishery. Overlooking fine-scale life-history dynamics coupled with scale-mismatch in science and management may perpetuate a …
An Analysis Of Neurogenesis In A Mouse Model Of Chemotherapy Related Cognitive Impairment, Maxwell A. Hennings
An Analysis Of Neurogenesis In A Mouse Model Of Chemotherapy Related Cognitive Impairment, Maxwell A. Hennings
Electronic Theses and Dissertations
Cancer patients treated with adjuvant chemotherapy often experience cognitive decline following treatment. This phenomenon, often dubbed “chemo brain” or “chemo fog” is usually temporary, but for a subset of survivors, these cognitive impairments can be long-lasting (>10 years) and negatively affect patients’ quality of life, career performance, and social fulfillment. While it is unclear what neurobiological mechanisms underlie chemotherapy related cognitive impairment, the majority of the animal literature has focused on adult neurogenesis. One process important for neurogenesis is the proliferation of new neurons within the dentate gyrus of the hippocampus. It is evident that many chemotherapy agents can …