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Articles 1 - 5 of 5
Full-Text Articles in Life Sciences
Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline
Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline
Electronic Theses and Dissertations
This dissertation attempts to discover the mechanisms between cardiovascular and respiratory motor control post spinal cord injury (SCI): in normal, non-injured (NI) persons, cardiovascular regulation is dependent upon respiration, but there is nothing that suggests the mechanism for this relationship post-SCI. Thus we hoped to evaluate various aspects of cardiovascular regulation to further illustrate how this relationship is changed or unchanged by SCI. Chapter I describes the anatomy and physiology of the spine, respiratory system, and cardiovascular system in a NI person, and then describes how the function of these systems is changed by SCI. In addition, we describe therapies …
Exercise Mitigates The Effects Of Hyperhomocysteinemia On Adverse Skeletal Muscle Remodeling., Lee Winchester
Exercise Mitigates The Effects Of Hyperhomocysteinemia On Adverse Skeletal Muscle Remodeling., Lee Winchester
Electronic Theses and Dissertations
Background: Hyperhomocysteinemia (HHcy) is heavily implicated in diabetes and cardiovascular disease. HHcy is known for causing inflammation and vascular remodeling, particularly through production of reactive oxygen species (ROS) and matrix metalloproteinase-9 (MMP-9). Although its impact on skeletal muscle is rather unclear, HHcy is known to cause skeletal muscle weakness and functional impairment. The impact of HHcy on inflammation makes it seem likely that HHcy causes skeletal muscle fibrosis through induction of inflammatory factors and destructive macrophages. Exercise has been shown to reduce homocysteine levels and therefore, could serve as a promising intervention for HHcy. The purpose of this study was …
Combination Treatment With Conjugated Linoleic Acid And Nitrite Protects Against Myocaridal Infarction., Natia Qipshidze Kelm
Combination Treatment With Conjugated Linoleic Acid And Nitrite Protects Against Myocaridal Infarction., Natia Qipshidze Kelm
Electronic Theses and Dissertations
According to the CDC, the most common type of heart disease is coronary artery disease, which frequently leads to myocardial infarction (MI). Therapeutic approaches to lessen the resulting cardiovascular injury associated with MI are limited. Recently, the management paradigm for cardiac injury has entered the molecular era and microRNAs (miRNAs) have been shown to act as negative regulators of gene expression by inhibiting mRNA translation and/or stimulating mRNA degradation. A single miRNA can modulate physiological or disease phenotypes by regulating whole functional systems. Importantly, miRNAs can regulate cardiac function, thereby modulating heart muscle contraction, heart growth and morphogenesis. MicroRNA-499 (miRNA-499) …
Thrombospondin-1 Decreases No-Mediated Vasodilation In Coronary Arterioles In Advancing Age., Grant Mckenzie
Thrombospondin-1 Decreases No-Mediated Vasodilation In Coronary Arterioles In Advancing Age., Grant Mckenzie
College of Arts & Sciences Senior Honors Theses
No abstract provided.
Pulmonary Diffusing Capacity Is Unaltered In Elite Swimmers After Restricted Breathing Training., Benjamin Todd Ogle 1990-
Pulmonary Diffusing Capacity Is Unaltered In Elite Swimmers After Restricted Breathing Training., Benjamin Todd Ogle 1990-
Electronic Theses and Dissertations
Controlled frequency breath (CFB) holding is a swim training modality that involves holding one’s breath for ~12 strokes before taking another breath. We looked to examine the effects of CFB training on pulmonary diffusing capacity for nitric oxide (DLNO) and carbon monoxide (DLCO). Elite swimmers (n = 25) were divided into either the CFB or a group that breathed regularly, every ~3rd stroke. The training intervention included 16 sessions of 12 x 50-m repetitions with either breathing pattern. Approximately 60% of the males and ~20% of the females were above the upper limits of normal for diffusing capacity at baseline. …