Life Sciences Commons^™

Thermoregulatory Dysfunction In Multiple Sclerosis Patients During Moderate Exercise In A Thermoneutral Environment, Mu Huang, Nathan Morris, Ollie Jay, Scott Davis

International Journal of Exercise Science: Conference Proceedings

Impairments in sudomotor function during passive heat stress have been reported in multiple sclerosis (MS), a demyelinating disease of the CNS that disrupts autonomic function. However, little is known regarding exercise induced increases in core body temperature on thermoregulatory mechanisms in MS. Thus, the aim of this study was to test the hypothesis that thermoregulatory function is impaired in MS patients compared to healthy controls (CN) during moderate exercise. Thermoregulatory function in five patients diagnosed with relapsing-remitting MS and five mass-matched healthy controls were compared during a single bout of cycling exercise (fixed workload of 70 Watts) for 30-60 minutes …

Do Elliptical Trainers Accurately Estimate Energy Expenditure?, Kevin Vallecillos, Edith Torres, Alberto Garcia, Kelsey Mclaughlin, Bethany Noack, Jorge Granados

International Journal of Exercise Science: Conference Proceedings

Life Fitness and Precor elliptical exercise trainers are very popular in fitness centers because of the reduced impact on joints as compared to running on a treadmill. Modern elliptical trainers measure heart rate, distance traveled, and provide an estimated amount of calories expended during the exercise bout. Each piece of equipment uses an internal algorithm to estimate energy expenditure based upon resistance and pedal rate. The purpose of this study was to determine if the PRECOR model EFX 556i and Life Fitness model 95X elliptical trainers accurately estimated energy expenditure. Three men and three women performed exercise sessions on each …

Effects Of Regular Exercise On Blood Components And Serum Lipids In Elderly With Low Cognitive Function, Nan Hee Lee, Chung Moo Lee, Sukho Lee

International Journal of Exercise Science: Conference Proceedings

Exercise is known as an effective method to reduce morbidity related to the cognitive impairment in the elderly. It has been reported that combined exercise including aerobic exercise and resistance training promotes cardiovascular function to facilitate volumetric oxygen transfer into brain and body tissues. The purpose of the present study was to determine the changes of blood components (RBC, WBC, HCT, Hb, MCV, MCH, Platelet) and serum lipids (TC, TG, HDL-c, LDL-c) by regular combined exercise in elderly with low cognitive function. 18 elderly women out of 23 completed all study requirements in this study. Following a baseline screening session …

Doms After Acute Strenuous Exercise And Massage, Cathleen Holub, John D. Smtih

International Journal of Exercise Science: Conference Proceedings

The art of massage therapy has been around for centuries and investigation of its effects on the human body continues. Purpose: This study is designed to determine if Swedish massage therapy reduces DOMS at 24- and 48-hours after a single bout of resistance exercise to fatigue. Methods: Twenty one volunteers completed a bout of body squats to exhaustion holding a 3.63 kg (8 lb.) weight for men and a 2.27 kg (5 lb.) for women, and after a one-minute rest did the same again but without the weight. This was immediately followed by a 20-minute Swedish massage on …

Voluntary Exercise Reduces Alzheimer’S-Like Pathology After Inflammation In Mice, Marielle K. Weintraub, Jordon D. White, Stephanie M. Turner, Samantha L. Hodges, Amanda Leigh Morin, Lindsey N. Sadler, Gary W. Boehm, Michael J. Chumley

International Journal of Exercise Science: Conference Proceedings

Current global statistics estimate that 44.4 million people are afflicted with dementia, and that 50%-75% of these patients suffer from Alzheimer’s disease (AD; Prince et al. 2013). AD, a progressive disorder categorized by neuronal and behavioral deterioration, is the 6^th leading cause of death in America (Alz facts and figure 2012). One hallmark pathology of AD is the presence of amyloid-beta (Aβ) in the brain, which can limit cell-to-cell communication, leading to cognitive deficits, and neuronal cell death. Although the exact origins of this disease still remain unknown, one possible catalyst of AD pathology is inflammation. Our lab has …

Effect Of Extracted Garlic Powder Ingestion For Two Months On Exercise-Induced Immunological Responses, Ayaka Sunami, Hiroshi Tamura, Mikako Sunaga, Naoki Katori, Akira Yokota, Syuichi Kusano, Toshiaki Kodama, Takahiro Yoshizaki, Yuri Yokoyama, Ayumi Nakai, Jyun Yasuda, Yuki Tada, Azumi Hida, Yuko Hasegawa, Yukari Kawano

International Journal of Exercise Science: Conference Proceedings

Introduction. Exhaustive exercise is associated with an increased risk of upper respiratory tract infection. Previously, allicin supplementation has been reported to reduce the incidence of common cold symptoms and production of exercise-induced interleukin (IL)-6. However, it is not clear if daily ingestion of the edible portion of whole garlic (Allium sativum) alters the exercise-induced immunological response. The present study investigated the effects of extracted garlic powder ingestion for 2 months on immune cell counts, natural killer cell activity (NKCA), as well as changes in cytokines, cortisol, and lactic acid in response to high-intensity cycling exercise.

Methods. The present …

Auto Anti Oxldl, Igm And Igg: Comparison Between Sedentary And Athletes, Juliana M B Santos, André L L Bachi, Francisco J O Rios, Tiago L. Capel, Pedro H C Vaisberg, Gislene R. Amirato, Mauro Vaisberg

International Journal of Exercise Science: Conference Proceedings

Introduction: The practice of regular physical activity contributes to reduce the prevalence of coronary hearth disease (CHD) and aerobic exercises are associated with beneficial changes in the profile of circulating lipids and lipoproteins. However in the past years the oxidative hypothesis assumed great importance in the pathogenesis of CHD. During exhaustive exercises there is a greater possibility of oxidation of LDL, forming oxidized LDL (oxLDL) that has a key role in atherogenesis. However the incidence of coronary events in athletes is lower than in sedentary persons. It is described in the literature that we can found in serum auto autoantibodies …

Changes Of Cytokines In Mouse Skeletal Muscle And Plasma By A Single Bout Of Endurance Exercise., Minjung Lee, Noriaki Kawanishi, Koichi Yada, Yungli Hung, Tsubasa Mizokami, Hiroyuki Niihara, Katsuhiko Suzuki

International Journal of Exercise Science: Conference Proceedings

Introduction: Exercise influences some cytokine levels, which is considered the body’s reaction against endogenous stress. Previous human studies demonstrated that high intensity exercise contributes to a dramatic increase of plasma cytokines like Interleukin-6 (IL-6) and Interleukin-1 receptor antagonist (IL-1ra) immediately after exercise. Recently, it has been identified that skeletal muscle produces cytokines and peptides and they exert both paracrine and endocrine effects. However, the sequential changes of cytokine production according to exercise conditions such as intensity, types and working time are still unclear. In this study, we identified the sequential changes of cytokines in both skeletal muscle and plasma after …

The Effects Of Exercise On Depression And Quality Of Life In Active And Sedentary Floor Nurses, Patrick B. Collins Ms, Acsm-Hfs

International Journal of Exercise Science: Conference Proceedings

Surveys were sent to all nursing staff (n=550) at a West Texas hospital. A total of 158 nurses responded and 112 nurses met the criteria for inclusion (16 male, 96 female). The surveys analyzed health-related quality of life using the SF-36 and depression scores using the PHQ-9. Data regarding exercise frequency, intensity, time, and type were also gathered. Results of the survey were then analyzed using SPSS statistical software to search for a relation between exercise, depression, and health-related quality of life. After determining that age and gender did not have a significant effect in the study, it was found …

Where College Students Live Can Impact Their Eating And Exercise Habits, Dong Woo Hahn, Aram Yoon, Kijeong Kim, Sukho Lee

International Journal of Exercise Science: Conference Proceedings

University freshmen usually face with huge environmental changes. They are often stressful and may lead to some health-related problems. We wanted to know whether or not their residence influences eating and exercising habits. PURPOSE: To examine the effect of residence on level of physical activity, eating and other health related habits in college students. Methods: Total 71 college students participated in this study. Thirty one lives on campus and forty lives off campus. Participants completed a consent form and measurements of body weight, height, and body mass index (BMI). Level of physical activity was monitored using pedometer for 7 days. …

Nursing With Eating, Activity, And Supportive Environment (Ease) : Effects Of An Eight-Week Mentoring Program, April V. Lane Hartmann, Laura Van Winkle-Preston, Peggy Mancuso, Gayle Roux, Shannon Scott, Nancy M. Dimarco

International Journal of Exercise Science: Conference Proceedings

Each year, approximately 2.8 million adults die from complications related to obesity (World Health Organization, 2011). One in three adults aged 20 years or older is obese, and 6% are morbidly obese. This problem is increasing at an alarming rate in young adults, and 20.5% of college students are classified as being overweight based upon their body mass index (BMI) (Adderley-Kelly, 2007). The purpose of this study was to increase knowledge about evidence-based, effective interventions that will enable college-aged, pre-nursing students to attain physical and mental well-being. The participants (N=24) were freshman and sophomore pre-nursing majors who were randomized into …

Cerebrovascular Hemodynamics During Concentric And Eccentric Phases Of Heavy Resistance Exercise, Gilbert Moralez, Steven A. Romero, Caroline A. Rickards, Peter B. Raven, William H. Cooke

International Journal of Exercise Science: Conference Proceedings

Rapid and drastic fluctuations in arterial blood pressures, such as those occurring during heavy resistance exercise pose a unique challenge to the maintenance of cerebral perfusion. During high-intensity leg cycling, regulation of cerebral perfusion is reduced by rapid decreases in beat-to-beat fluctuations in blood pressure (diastolic phase) rather than rapid increases (systolic phase). The purpose of this study was to test the hypothesis that rhythmic heavy resistance exercise will similarly impair the regulation of cerebral blood flow during the diastolic phase of beat-to-beat fluctuations in pressure. We studied seven healthy male subjects. Beat-to-beat finger arterial pressures, and middle cerebral artery …

Gender Differences In Skin And Core Body Temperature During Exercise In A Hot, Humid Environment., Adam S. Venable, Randall R. Williams, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

Background. It is universally accepted that men and women regulate heat differently during exercise in hot, humid environments. Despite this common knowledge, little empirical data is available to explain how gender differences effect core/skin temperature changes. Further, the data that is available includes only limited measurement sites and/or time points. Methods. The purpose of this study was to measure the heat regulatory patterns for both men and women during 60-min of exercise in a hot, humid environment. Twenty aerobically fit subjects (10 men; 10 women) completed an acclimation session followed by a 60-min exercise protocol in an environmental chamber set …

Deptor Expression Correlates With Muscle Protein Synthesis, Kevin L. Shimkus, Elyse V. Wudeck, Yasaman Shirazi-Fard, Mats I. Nilsson, Nicholas P. Greene, Harry A. Hogan, James D. Fluckey

International Journal of Exercise Science: Conference Proceedings

Mammalian target of rapamycin (mTOR) has long been declared a focal point of muscle protein synthesis. mTORC1 (an mTOR complex consisting of mTOR, raptor, PRAS40, and mLST8) has been associated with regulation of protein translation in muscle, altering expression and activity levels of key downstream targets S6K1 and eIF-4E-BP1. mTORC1 has been shown to be affected by various stimuli, including nutritional status, growth factors, and mechanical loading. But in past incidents we have found disconnects in muscle protein synthesis and mTOR signaling, stimulating discussions that mTOR content and activation alone may not be able to fully account for muscle protein …

Exercise Ameliorates Disruption Of The Dystrophin-Associated Glycoprotein Complex And Fibrosis In The Aging Rat Heart, Yang Lee, Jeffrey M. Hord, Hyo-Bum Kwak, Jong-Hee Kim, John M. Lawler

International Journal of Exercise Science: Conference Proceedings

The dystrophin-glycoprotein complex (DGC) is localized and integrated into the cell membrane. The DGC provides a mechanical link between the cellular cytoskeleton and the extracellular matrix (ECM). In cardiac muscle, disruption of DGC might be involved in mediating cardiac remodeling that occurs with aging, cardiomyopathy, and heart failure through transforming growth factor-beta (TGF-ß). Decorin is a small leucine-rich proteoglycan closely related to the DGC component that binds to collagen. Decorin reduces fibrosis via inhibition of TGF-ß and myofibroblast formation. PURPOSE: To test the hypothesis that exercise training (ET) would alleviate age-related disruption of localization in DGC proteins (dystrophin, α-syntrophin, and …

Influence Of Fitness And Adiposity On Melanocortin-1 And Melanocortin-3 Receptors On Monocytes., Matthew Unthank, Jonathan Woodson, Jason Butler, Gregory Bratton, James Barbee, Michael Chumley, Dennis Cheek, Joel Mitchell, Melody Phillips

International Journal of Exercise Science: Conference Proceedings

Purpose: While it is known that exercise improves health by reducing systemic inflammation, potential mechanisms remain to be elucidated. The purpose of this study is to examine the influence of fitness and adiposity on the anti-inflammatory melanocortin system as a potential mechanism by which exercise reduces inflammation. Methods: Forty-one men and women (35-55yr), who were free from cardiovascular disease, inflammatory disorders, and not taking medications that affect inflammation, were recruited. Participants were questioned about exercise habits and medical history; then completed testing for body composition and aerobic fitness (VO₂max). Subjects were classified as lean/fit (LF, n=14), overweight/fit (OF, …

Changes In Markers Of Muscle Damage After Half-Ironman Triathlon, Marcos Bürger-Mendonça, Fernanda Coutinho Retondaro-Barbosa, Raquel Carius Da Silveira, Denisvaldo Vieira Silveira

International Journal of Exercise Science: Conference Proceedings

Triathlon is a unique endurance sport that comprises a sequential swim, swim-to cycle transition, cycle, cycle-to-run transition, and run. The aim of present was to analyze the effect of half-ironman triathlon over biochemistry parameters related of muscle damage. Six well-trained male amateurs’ triathletes who completed the 2004 half-ironman triathlon participated in the study. Blood samples from six athletes were collected before and immediately after the triathlon competition. Creatinine kinase (CK) and lactate dehydrogenase (LDH) were measured. Pre and post race values were compared by paired t-tests. Significant changes after triathlon completion were found for CK (P= 0.001) and LDH (P= …

Plasmatic E-Selectin Levels Were Decreased In Young Women With Metabolic Syndrome After Exercise Training, M Rosety-Rodriguez, I Rosety, G Fornieles-Gonzalez, J Meletis

International Journal of Exercise Science: Conference Proceedings

Cellular adhesion molecules (CAMs) such as E-selectin are involved in the rolling, adhesion and extravasation of monocytes into the atherosclerotic plaque. Fortunately regular exercise may improve pro-inflammatory status in individuals with metabolic syndrome. Accordingly, this study was designed to determine the influence of exercise on soluble plasmatic E-selectin levels in women with metabolic syndrome. Sixty adult women with metabolic syndrome according to the criteria reported by the National Cholesterol Education Program Adult Treatment Panel III volunteered for this study. Fourty-five were randomly included in experimental group to perform a 12-weeks aerobic training program, 3 days/week, consisting of warm up (10-min), …

Reduced Lipoperoxidation In High-Performance Athletes With Mental Retardation By A Mixed Protocol Based On Exercise And Supplementation, J F. Ordoñez, I Rosety, A Diaz, M A. Rosety

International Journal of Exercise Science: Conference Proceedings

Individuals with mental retardation generally present high levels of oxidative stress. Further it is widely accepted that high physical performance may be associated to oxidative damage. The present study was undertaken to ascertain the influence of a mixed protocol based on regular exercise and antioxidant supplementation in lipoperoxidation in athletes with mental retardation. Fifty-five high-performance athletes with mental retardation from Special Olympics volunteered for this study (21.6±1.8 years-old). Fourty were randomly included in experimental group to perform a 6-weeks protocol, including exercise (low-moderate intensity aerobic exercise before breakfast 3 times per week) and supplementation (1g ascorbic acid + 400 UI …

A Previous Note Regarding The Influence Of A 6-Weeks Mixed Protocol On Plasmatic Carbonyl Groups In High-Performance Athletes With Mental Retardation, J F. Ordonez, I Rosety, M Bernardi, A Diaz

International Journal of Exercise Science: Conference Proceedings

It is widely accepted that high physical performance may be associated to oxidative damage. The present study was undertaken to ascertain the influence of a mixed protocol based on regular exercise and antioxidant supplementation in plasmatic carbonyl group content in athletes with mental retardation. Mainly if we take into account individuals with mental retardation generally present high levels of oxidative damage. Fifty-five high-performance athletes with mental retardation from Special Olympics volunteered for this study (21.6±1.8 years-old). Fourty were randomly included in experimental group to perform a 6-weeks protocol including exercise (low-moderate intensity aerobic exercise before breakfast 3 times per week) …

Exercise Improves Endothelial Dysfunction In Young Women With Metabolic Syndrome, G Fornieles-Gonzalez, I Rosety, J Meletis, M A. Rosety

International Journal of Exercise Science: Conference Proceedings

Recent studies have reported that regular exercise reduces pro-inflammatory biomarkers in women with metabolic syndrome. However, to date little information is available on the influence of exercise on endothelial dysfunction, despite its important role during the development of atherosclerotic plaque. Accordingly, this study was designed to determine the influence of exercise on soluble vascular cell adhesion molecule (VCAM-1) in women with metabolic syndrome. Sixty adult women with metabolic syndrome according to the criteria reported by the National Cholesterol Education Program Adult Treatment Panel III volunteered for this study. Fourty-five were randomly included in experimental group to perform a 12-weeks aerobic …

Influences On Pulmonary And Muscular V’O2-Kinetics, Uwe Drescher, Uwe Hoffmann

International Journal of Exercise Science: Conference Proceedings

Introduction

Muscular and respiratory V’O2-kinetics are influenced by many factors. At cellular level muscular V’O2 (V’O2musc) is affected by O2-delivery and O2-consumption. Further, these factors can be divided into muscle perfusion, capillary density, enzyme activity, mitochondrial proliferation, muscle fiber composition and some more.

Focusing on the difference between V’O2resp and V’O2musc the venous blood volume, the venous O2-stores and the dynamics of cardiac output can be identified as influences. These influences result in a time delay and a distortion of V’O2resp. Usually exercise step responses are used for estimating V’O2resp-kinetics. But it has to be recognized, that V’O2resp may be …

Effect Of Hsv-1 Infection On The Exercise-Induced Mobilization Of T-Cell Subsets, Emily C.P. Lavoy, J. Austin Bigley, Mark R. Morrison, Guillaume Spielmann, Jerrald L. Rector, Richard J. Simpson

International Journal of Exercise Science: Conference Proceedings

Acute exercise mobilizes highly-differentiated memory and senescent T-cells into the blood compartment, which could have important implications for post-exercise immune surveillance. This response differs in individuals with latent cytomegalovirus (CMV) infection (a herpesvirus), but it is unknown if other latent herpesviruses, such as herpes simplex virus type 1 (HSV-1), also influence this exercise-induced immune response. As HSV-1 infects 50% of the US population, this could have implications for many athletes. PURPOSE: To examine the effects of an acute bout of exercise on the frequency and relative proportion of naïve, memory, and senescent T-cells in the peripheral blood in HSV-1 infected …

Cognitive Behavior Modification And Exercise + Group Counseling For Patients After Bariatric Surgery, Janet Buckworth, Caroline Carducci, Shirley Kindrick, Dean Mikami, Dara Schuster, Katharine Stough, Bradley Needleman

International Journal of Exercise Science: Conference Proceedings

The growing obesity epidemic is paralleled by an increasing number of bariatric surgeries. Patients lose significant weight within the first 12-18 months post-surgery with corresponding resolution of many co-morbidities. However, weight loss stabilizes after 18-24 months and 50% or more of patients eventually regain weight (Bond, Phelan, Leahey, Hill, & Wing, 2009; Magro, et al., 2008). Weight regain after loss is associated with return of co-morbidities and deteriorations in health-related quality of life and mood (Karlsson, Taft, Ryden, Sjostrom, & Sullivan, 2007). The purpose of this pilot study was to analyze the effects of a post-surgical behavioral plus counseling intervention …

The Impact Of Latent Cmv Infection On Nk-Cell Mobilization And Expression Of Klrg1 And Cd57 In Response To Acute Exercise., Austin B. Bigley, Guillaume Spielmann, Jerrald L. Rector, Richard J. Simpson

International Journal of Exercise Science: Conference Proceedings

Natural killer (NK) cells are cytotoxic effectors of the innate immune system that are able to distinguish healthy autologous cells from tumors and virally infected cells. NK-cells kill the targeted cells by releasing cytotoxic proteins, a process that is governed by inhibitory surface receptors, such as KLRG1. Additionally, activated NK-cells are able to proliferate in response to immunological stimuli, a process that is inhibited in NK-cells expressing the senescence marker CD57. Acute bouts of exercise are known to mobilize NK cells into the blood compartment, which could alter immunity; however, whether or not exercise alters NK-cell KLRG1 and CD57 expression …

Short-Term Changes In Ldl Density And Lipoprotein Particle Number In Trained Men After 3 Different Modes Of Exercise, Jonathan M. Oliver

International Journal of Exercise Science: Conference Proceedings

Short-Term Changes in LDL Density and Lipoprotein Particle Number in Trained Men After 3 Different Modes of Exercise Jonathan M. Oliver, Steven E. Martin, Shawn P. Glowacki, Wade Womack, John S. Green, FACSM, and Stephen F. Crouse, FACSM, Texas A&M University, TX 77843, (Sponsor: S. F. Crouse) PURPOSE: To determine the short-term changes in LDL density and lipoprotein particle number after three different modes of exercise in trained men. METHODS: Twenty seven subjects were randomly assigned to complete either (resistance [RE], endurance [EE], or combination resistance/endurance [CE]) exercise. Fasting blood samples were obtained 24 h before (baseline) and 24 h …

Changes In Pparδ Protein Content Following Acute Aerobic Exercise In Human Vastus Lateralis Muscle., Nicholas P. Greene, Mats I. Nilsson, Bradley S. Lambert, Steven E. Riechman, James D. Fluckey, Stephen F. Crouse

International Journal of Exercise Science: Conference Proceedings

PPARδ is a transcription factor which functions in the regulation of lipid and glucose metabolism, and may be implicated as a therapeutic target for several metabolic diseases. Exercise training has previously been shown to increase PPARδ protein content, but the response of PPARδ to acute exercise is not yet understood. PURPOSE: To explore changes in PPARδ protein content following an acute bout of aerobic exercise in untrained obese adults. METHODS: 8 men and 4 women participated in the study. Subjects’ mean age, weight, VO2MAX (Bruce treadmill GXT), and body composition (DEXA) were 44 yr, 93.2 kg, 28.2 mL/kg/min, and 40.5% …

Influence Of Caloric Expenditure On Postprandial Triglyceride And Glucose Responses Following A High-Carbohydrate Meal, James Rowe, Heidi Bistrup, Kelley Henry, Melinda Villarreal, Kyle D. Biggerstaff, Vic Ben-Ezra

International Journal of Exercise Science: Conference Proceedings

Purpose: To examine the effects of aerobic exercise expending 350 and 700 kcal of energy on postprandial triglyceride (Tg) and glucose responses following a high carbohydrate (CHO) meal. Methods: Non-active individuals (n=9 women/4 men; age=22.8±3.7 yrs; Ht=169±10.4 cm; Wt=75.7± 22.4 kg; BMI=26.1±5.8 kg/m2; VO2 max=34.1±6.9 ml/kg/min) completed three trials in a random order: 1) control trial, 2) single exercise session expending 350 kcal (EX350), and 3) single exercise session expending 700 kcal (EX700). Exercise consisted of treadmill walking at 60% VO2 max until 350 and 700 kcal of energy had been expended. The control session consisted of seated rest. The …