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Full-Text Articles in Life Sciences
Synapse-Associated Protein 102 – A Highly Mobile Maguk Predominate In Early Synaptogenesis, Dominique Alexandra De Los Reyes, Mohammad Yaman Karkoutly, Yonghong Zhang
Synapse-Associated Protein 102 – A Highly Mobile Maguk Predominate In Early Synaptogenesis, Dominique Alexandra De Los Reyes, Mohammad Yaman Karkoutly, Yonghong Zhang
School of Integrative Biological and Chemical Sciences Faculty Publications and Presentations
Neurodevelopmental and neurodegenerative disorders are primarily characterized by serious structural and functional changes in excitatory glutamatergic synapses in the brain, resulting in many synaptic deficits and aberrant synapse loss. It is a big challenge to reverse these synaptic impairments as a treatment for neurological diseases in the field. Extensive research on glutamate receptors as therapeutic targets has been done but with little success shown in human trials. PSD-95-like MAGUK proteins perform a pivotal role in regulating the trafficking and stability of glutamate receptors that are important to postsynaptic structure and function. MAGUK and MAGUK-modulated synaptic pathways are becoming promising candidates …
Wrap-Around Services To Older Adults With Dementia: Collaboration, Education, And Prevention As A Model For Integration Of Primary Care And Neurobehavioral Health, Gladys E. Maestre, Francisco Fernandez
Wrap-Around Services To Older Adults With Dementia: Collaboration, Education, And Prevention As A Model For Integration Of Primary Care And Neurobehavioral Health, Gladys E. Maestre, Francisco Fernandez
School of Medicine Publications and Presentations
Background: Medical care in the Rio Grande Valley (RGV) is fragmented and difficult to navigate, especially for older adults with cognitive decline and dementia. The communities are eager to have a new healthcare delivery system that integrate community-based aging services to provide integrated, team collaborative better health care in our communities. The University of Texas RGV School of Medicine, in collaboration with its affiliates in the regional healthcare systems, is a partner providing comprehensive care across the life-cycle bridging science, social services and patient care. Our interprofessional team collaborative emphasizes safe, appropriate, and effective neurobehavioral care, employing evidence-based medicine in …
A Global Perspective On The Influence Of Environmental Exposures On The Nervous System, Desire Tshala-Katumbay, Jean-Claude Mwanza, Diane S. Rohlman, Gladys E. Maestre, Reinaldo B. Oria
A Global Perspective On The Influence Of Environmental Exposures On The Nervous System, Desire Tshala-Katumbay, Jean-Claude Mwanza, Diane S. Rohlman, Gladys E. Maestre, Reinaldo B. Oria
School of Medicine Publications and Presentations
Economic transitions in the era of globalization warrant a fresh look at the neurological risks associated with environmental change. These are driven by industrial expansion, transfer and mobility of goods, climate change and population growth. In these contexts, risk of infectious and non-infectious diseases are shared across geographical boundaries. In low- and middle-income countries, the risk of environmentally mediated brain disease is augmented several fold by lack of infrastructure, poor health and safety regulations, and limited measures for environmental protection. Neurological disorders may occur as a result of direct exposure to chemical and/or non-chemical stressors, including but not limited to, …
Category-Selective Attention Interacts With Partial Awareness Processes In A Continuous Manner: An Fmri Study, Shen Tu, Jerwen Jou, Qian Cui, Guang Zhao, Kangcheng Wang, Glenn Hitchman, Jiang Qiu, Qinglin Zhang
Category-Selective Attention Interacts With Partial Awareness Processes In A Continuous Manner: An Fmri Study, Shen Tu, Jerwen Jou, Qian Cui, Guang Zhao, Kangcheng Wang, Glenn Hitchman, Jiang Qiu, Qinglin Zhang
Psychological Science Faculty Publications and Presentations
Recently, our team found that category-selective attention could modulate tool processing at the partial awareness level and unconscious face processing in the middle occipital gyrus (MOG). However, the modulation effects in MOG were in opposite directions across the masked tool and masked face conditions in that study: MOG activation decreased in the masked faces condition but increased in the masked tools condition under the consistent compared with the inconsistent cue-selective-attentional modulation. In the present study, in order to confirm that the opposite effects were due to the changed contours of the tools, using the same tool pictures and fMRI technique, …