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Full-Text Articles in Life Sciences
Polymorphisms Of The 5-Httlpr Gene: Associations To Ern And Depression, Curtis Killpack, Michael J. Larson
Polymorphisms Of The 5-Httlpr Gene: Associations To Ern And Depression, Curtis Killpack, Michael J. Larson
Journal of Undergraduate Research
Our aim with this study of polymorphisms in the serotonin transporter gene (5-HTTLPR) was to investigate the association between performance monitoring capabilities (i.e., detecting errors in performance using the error-related negativity [ERN] component of the scalp recorded event-related potential [ERP]) against three variations of gene 5-HTTLPR allelic pairs: homozygous short (S/S), heterozygous short-long (S/L), and homozygous long (L/L). The serotonin transporter gene is associated with our ability to cope with stress and regulate serotonin, which affects mood, social behavior, appetite, and sleep (Adam, Doane, Zinbarg, Mineka, Craske, & Griffith, 2010). Previous studies (Barnes, Dean, Nandam, O’Connell, & Bellgrove, 2011) have …
The Role Of Bdnf Expression In Chronic Ethanol Usage, Caleb Porter, Scott Steffensen
The Role Of Bdnf Expression In Chronic Ethanol Usage, Caleb Porter, Scott Steffensen
Journal of Undergraduate Research
It has been observed that chronic exposure to drugs of abuse, particularly opiates, increases brain-derived neurotrophic factor (BDNF) levels in ventral tegmental area (VTA) neurons. In particular, BDNF expression is dramatically increased during drug withdrawal, which would suggest a direct connection between the aversive state of withdrawal and BDNFinduced neuronal plasticity. The purpose of this project was to evaluate the relationship between brain-derived neurotrophic factor (BDNF) expression, which is dramatically increased within the ventral tegmental area (VTA) during drug abuse, and alcohol withdrawal symptoms.
Role Of Exercise And Stress In Memory And Learning Of The Hippocampus, Paul Baker, Jeff Edwards
Role Of Exercise And Stress In Memory And Learning Of The Hippocampus, Paul Baker, Jeff Edwards
Journal of Undergraduate Research
Some of the most devastating diseases today are diseases of the mind. Common side effects of Alzheimer’s disease are dementia and memory loss and more than 44 million people suffer from the disease worldwide [1]. Other mental diseases such as Parkinson’s also have a dramatic impact on the memory and learning pathways. Understanding the mechanism involved with memory and learning will bring science that much closer to finding a permanent cure to these devastating diseases.