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Integrative Biology

The University of Akron

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C57BL6

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Case Study: Observing The Effects Of Length Of Exposure To Mnv On Mice Colonies, Beau Brown Jan 2016

Case Study: Observing The Effects Of Length Of Exposure To Mnv On Mice Colonies, Beau Brown

Williams Honors College, Honors Research Projects

Four groups of experimental mice are studied in this experiment following intentional exposure to murine norovirus (MNV). Two groups are exposed to the virus at different points in their lives, and the other two are not infected and studied alongside the other groups as controls.

Past research has indicated that B and T immune cells are not essential to MNV resistance. Additionally, antibody production against MNV has shown to be slow as infection progresses. Thus, the expected results from the experiment are that the mice with longer infections of MNV will have larger quantities of IgG than those more recently …