Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Status Of The Major Oyster Diseases In Virginia 2000 A Summary Of The Annual Monitoring Program, Lisa M. Ragone Calvo, Eugene M. Burreson
Status Of The Major Oyster Diseases In Virginia 2000 A Summary Of The Annual Monitoring Program, Lisa M. Ragone Calvo, Eugene M. Burreson
Reports
As a consequence of the relatively warm temperatures, high salinities, and high oyster parasite abundances in the fall of 1999, both P. marinus and H. nelsoni were widely distributed throughout oyster populations in Virginia in 2000. Fortunately, however, we did not see severe epizootics of the diseases as observed in some areas in 1999.
Reduction In Dna Binding Activity Of The Transcription Factor Pax-5a In B Lymphocytes Of Aged Mice, J Anspach, G Poulsen, I Kaattari, R Pollock, P Zwollo
Reduction In Dna Binding Activity Of The Transcription Factor Pax-5a In B Lymphocytes Of Aged Mice, J Anspach, G Poulsen, I Kaattari, R Pollock, P Zwollo
VIMS Articles
Aging has been associated with intrinsic changes of the humoral immune response, which may lead to an increased occurrence of autoimmune disorders and pathogenic susceptibility. The transcription factor Pax-5 is a key regulator of B cell development. Pax-5a/B cell-specific activator protein and an alternatively spliced isoform, Pax-Sd, may have opposing functions in transcriptional regulation due to the lack of a transactivation domain in Pax-Sd. To study B cell-specific changes that occur during the aging process, we investigated expression patterns of Pax-Sa and Sd in mature B cells of young and aged mice. RNase protection assays showed a similar transcriptional pattern …