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Transcriptional Regulation Of Cell-Type Specific Expression In The Arabidopsis Root, Keegan M. Leckie

Electronic Thesis and Dissertation Repository

Characterizing transcription factor interactions with their corresponding binding sites is crucial for understanding how gene expression is regulated by DNA sequence. A more comprehensive understanding of this process could have benefits in synthetic promoter design and creation of genetically modified organisms. Herein, the promoters of genes exhibiting cell-type specific expression within a single layer of the Arabidopsis root are analyzed to identify cis-regulatory motifs implicated in cell-type specific expression. De novo motif prediction identifies multiple motif candidates overly represented in the promoter sequences of co-expressed genes specific for epidermal, cortex, and endodermal expression. Several endodermal specific putative motifs are …