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Genetics and Genomics

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Presidential Scholars Theses (1990 – 2006)

1999

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The Expression Of The Crf1 Gene In Mouse Embryonic Development, Margaret Gruber Jan 1999

The Expression Of The Crf1 Gene In Mouse Embryonic Development, Margaret Gruber

Presidential Scholars Theses (1990 – 2006)

A mouse gene cloned in the laboratory of James and Olivia Smith at Baylor College of Medicine was found to be involved in motor function. This gene was named CRFl for Clq-Related Factor 1, and using in situ hybridization, it was found to be expressed mainly in the brainstem of adult mice. There is a gene similar to the CRFl gene in humans. By determining this gene's role in mouse development, more will be known about the development of human motor function.

To determine the stage of embryonic development at which the expression of this gene …