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Genetics

Inquiry: The University of Arkansas Undergraduate Research Journal

Journal

2003

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Full-Text Articles in Life Sciences

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles, E, E+, Erh, Rupali B. Ugrankar Jan 2003

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles, E, E+, Erh, Rupali B. Ugrankar

Inquiry: The University of Arkansas Undergraduate Research Journal

The melanocortin 1-receptor (MC1-R) gene plays a key role in the expression of fur and feather color in mammals and birds by regulating the distribution of two melanin pigments: eumelanin (black/brown) and pheomelanin (red/yellow). MC1-R corresponds to the classical Extension (E) locus in mice, pigs, dogs, horses, and chickens. Three E locus alleles, the wild-type (e + ), brown (E), and redhead (e rh) have been identified in Japanese quail (Coturnix japonica). To determine if the quail E locus phenotypes were due to variation in the MC1-R gene, the coding region of the MC1-R gene was PCR amplified and DNA …