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Anthocyanin-Containing Purple Potatoes Ameliorate Dss-Induced Colitis In Mice, Shiyu Li, Tianmin Wang, Baojun Xu, Vijay Indukuri, Jairam Vanamala, Lavanya Reddivari
Anthocyanin-Containing Purple Potatoes Ameliorate Dss-Induced Colitis In Mice, Shiyu Li, Tianmin Wang, Baojun Xu, Vijay Indukuri, Jairam Vanamala, Lavanya Reddivari
Department of Food Science Faculty Publications
Ulcerative colitis (UC), a major form of inflammatory bowel disease (IBD), is on the rise worldwide. Approximately three million people suffer from IBD in the United States alone, but the current therapeutic options (e.g., corticosteroids) come with adverse side effects including reduced ability to fight infections. Thus, there is a critical need for developing effective, safe and evidence-based food products with anti-inflammatory activity. This study evaluated the antiinflammatory potential of purple-fleshed potato using a dextran sodium sulfate (DSS) murine model of colitis. Mice were randomly assigned to control (AIN-93G diet), P15 (15% purple-fleshed potato diet) and P25 (25% purple-fleshed potato …