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Full-Text Articles in Life Sciences
Nutritional Regulation Of Sulfonamide Antibiotic Biodegradation By Microbacterium Sp. Strain C448, Tonya Malcolm
Nutritional Regulation Of Sulfonamide Antibiotic Biodegradation By Microbacterium Sp. Strain C448, Tonya Malcolm
Electronic Thesis and Dissertation Repository
Sulfonamide antibiotics are frequently released into the environment due to their widespread use in livestock production, imposing a potential selection pressure for the development and dissemination of sulfonamide resistance. Recently, a sulfonamide-degrading bacterium Microbacterium sp. Strain C448 was discovered, whose activity has the potential to be used as a sulfonamide removal strategy from agricultural soils. This research gains insight into the sulfonamide biodegradation pathway by 1) evaluating the nutritional regulation of sulfamethazine biodegradation and 2) undertaking a comparative proteomic analysis of cells grown in the presence and in the absence of sulfamethazine. The nutritional analyses revealed that increasing amounts of …
Bacterial Diversity Impacts As A Result Of Combined Sewer Overflow In A Polluted Waterway, Olga Calderón, Holly Porter-Morgan, Joby Jacob, Willis Elkins
Bacterial Diversity Impacts As A Result Of Combined Sewer Overflow In A Polluted Waterway, Olga Calderón, Holly Porter-Morgan, Joby Jacob, Willis Elkins
Publications and Research
Newtown Creek is an industrial waterway and former tidal wetland in New York City. It is one of the most polluted water bodies in the United States and was designated as a superfund site in 2010. For over a century, organic compounds, heavy metals, and other forms of industrial pollution have disrupted the creek’s environment. The creek is also impacted by discharges from twenty combined sewer overflow pipes, which may deposit raw sewage or partially treated wastewater directly into the creek during heavy or sustained rain events. Combined sewer overflow events and associated nutrient over-enrichment at the creek drive eutrophication …