Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- 5-fluorouracil (1)
- Azoxymethane (1)
- Beans peas lentils (1)
- CRISPR-Cas9 (1)
- Carbonation (1)
-
- Chronic diseases (1)
- Colorectal cancer (1)
- Conformational dynamics (1)
- Craft Brewing (1)
- Craft beer (1)
- DNA Sequencing (1)
- Diffuse reflectance spectroscopy (1)
- Drug Delivery (1)
- Duchenne Muscular Dystrophy (1)
- Eddy covariance (1)
- Emissions (1)
- Encapsulation (1)
- Engineering (1)
- Food production (1)
- Food systems (1)
- Gene Editing (1)
- Generalized additive models (1)
- Healthy and sustainable food choice (1)
- Irrigation (1)
- Life cycle assessment (1)
- Membrane proteins (1)
- Metal-organic Framework (1)
- Methane (1)
- Metronomic chemotherapy (1)
- Molecular dynamics simulations (1)
Articles 1 - 8 of 8
Full-Text Articles in Life Sciences
Sustainability And Health Impacts Of Pulse Crops In The United States Using Life Cycle Assessment, Prathamesh A. Bandekar
Sustainability And Health Impacts Of Pulse Crops In The United States Using Life Cycle Assessment, Prathamesh A. Bandekar
Graduate Theses and Dissertations
Environmental sustainability and human health impact of pulses produced and consumed in the United States was assessed using life cycle assessment (LCA). The study included three objectives 1) to estimate environmental impact of current production and consumption practices in the United States using attributional LCA; 2) to estimate environmental and human health impact of iso-caloric diets containing varying amounts of pulses using Hybrid-LCA and Combined Nutritional and Environmental-LCA (CONE-LCA); and 3) to estimate environmental impact of increased demand for pulses using consequential LCA. Scope of the study varied for each objective with system boundary encompassing cradle-to-grave activities for objective 1 …
A Study On Interactions Between Metal-Organic Frameworks And Biological Materials, Josh Phipps
A Study On Interactions Between Metal-Organic Frameworks And Biological Materials, Josh Phipps
Graduate Theses and Dissertations
Metal-organic frameworks or MOFs are an extremely useful tool in many areas of applications. Their popularity in recent years has arisen from their high efficiency in catalytic chemical reactions. This is made possible due to their porous interior and the ability of the MOFs components to be functionalized. These same traits make MOFs excellent for use in protein encapsulation or immobilization and have the potential to become excellent drug carriers. Their development in this utilization has been limited dramatically compared to MOFs chemical applications. This is due in part to the nature of biological processes taking longer to study, but …
Using Molecular Dynamics Simulations To Decipher Mechanistic Details Of Biomolecular Processes Of Biology And Biotechnology Oriented Applications, Adithya Polasa
Graduate Theses and Dissertations
Researchers in chemistry and biology often utilize computer simulations, in conjunction with experimental data, to model and predict the structures, energies, kinetics, processes, and functions of the systems that are their focus of study, ranging from single molecules to whole viruses. Here, we use molecular dynamics (MD) techniques to gain a deeper understanding of biomolecular processes in biology and biotechnology-oriented applications. Using a mixture of equilibrium and non-equilibrium MD simulations, this work describes the insertion process of YidC at the atomic level. In order to better comprehend the insertion process, several docking models of YidC-Pf3 in the lipid bilayer were …
Modeling The Impact And Accelerating The Process Of Transitioning To A Sustainable Healthy Diet Through Decision Support Systems, Prince Agyemang
Modeling The Impact And Accelerating The Process Of Transitioning To A Sustainable Healthy Diet Through Decision Support Systems, Prince Agyemang
Graduate Theses and Dissertations
Food production and consumption are essential in human existence, yet they are implicated in the high occurrences of preventable chronic diseases and environmental degradation. Although healthy food may not necessarily be sustainable and vice versa, there is an opportunity to make our food both healthy and sustainable. Attempts have been made to conceptualize how sustainable healthy food may be produced and consumed; however, available data suggest a rise in the prevalence of health-related and negative environmental consequences of our food supply. Thus, the transition from conceptual frameworks to implementing these concepts has not always been effective. This paper explores the …
The Effect Of Water Management And Ratoon Rice Cropping On Methane Emissions And Harvest Yield In Arkansas, Marguerita Leavitt
The Effect Of Water Management And Ratoon Rice Cropping On Methane Emissions And Harvest Yield In Arkansas, Marguerita Leavitt
Graduate Theses and Dissertations
Sustainable intensification of rice farming is crucial to meeting human food needs while reducing environmental impacts. Rice produces 8% of all anthropogenic CH4, which is a potent greenhouse gas. CH4 emissions can potentially be reduced by cultivation practices that minimize the number of days the fields are saturated, such as dry-seeding instead of water-seeding and irrigation using the alternate wetting and drying (AWD) technique instead of delayed, continuous flooding (DF). Ratoon cropping, wherein a second crop of rice is grown from the harvested stubble of the first crop, can be used to produce additional yield with minimal labor, but may …
The Effects Of Metronomic And Maximum-Tolerated Dose Chemotherapy In Colorectal Cancer Angiogenesis: A Combined Approach Using Endoscopic Diffuse Reflectance Spectroscopy And Mrna Expression, Ariel Isaac Mundo Ortiz
The Effects Of Metronomic And Maximum-Tolerated Dose Chemotherapy In Colorectal Cancer Angiogenesis: A Combined Approach Using Endoscopic Diffuse Reflectance Spectroscopy And Mrna Expression, Ariel Isaac Mundo Ortiz
Graduate Theses and Dissertations
Colorectal cancer (CRC) continues to be one of the most incident and deadliest types of cancer worldwide. Chemotherapy has proven effective to reduce tumor burden for CRC patients, but there are several disadvantages associated with the use of mainstay maximtolerated dose (MTD) chemotherapeutic strategies. Metronomic chemotherapy (MET) has been developed as an alternative that addresses the shortcomings of maximum-tolerated dose chemotherapy but so far its effectiveness as a neoadjuvant strategy for CRC has not been explored.
This dissertation uses a combined optics and molecular biology approach (using diffuse reflectance spectroscopy and mRNA expression) to study the changes in angiogenesis and …
Development Of A Long-Read Sequencing Protocol To Assess The Precision And Efficacy Of Gene Editing For Duchenne Muscular Dystrophy, Landon Andrew Burcham
Development Of A Long-Read Sequencing Protocol To Assess The Precision And Efficacy Of Gene Editing For Duchenne Muscular Dystrophy, Landon Andrew Burcham
Graduate Theses and Dissertations
This work establishes a method for assessing on-target precision due to CRISPR-Cas9 gene editing, especially within the context of exon skipping therapy for Duchenne Muscular Dystrophy. The proposed method utilizes an Oxford nanopore long-read sequencing approach to sequence amplified regions of DNA that have been edited using CRISPR-Cas9. NIH3T3 and C2C12 cell lines were treated with a dual-guide CRISPR-Cas9 system, that targets and deletes exon 23 from the DMD gene in mouse samples. Deletion PCR revealed deletion of exon 23 in both DNA and cDNA samples. Additionally, sequencing using Oxford Nanopore revealed targeted exon 23 deletion as the most prevalent …
An Engineering And Economic Analysis Of The Implementation Of The Carbo Rock-It, Lydia Huck
An Engineering And Economic Analysis Of The Implementation Of The Carbo Rock-It, Lydia Huck
Graduate Theses and Dissertations
The patented Carbo Rock-It system was developed to carbonate beverages for the craft brewing industry with the goal of reducing time, cost, and environmental impacts of the carbonation process. This research field tests, models, analyzes and optimizes the engineering and economic performance of a commercial-scale Carbo Rock-It placed in production at an operating brewery (Core Brewing and Distilling Co., Springdale, AR). Field tests indicated that the Carbo Rock-It was able to successfully carbonate twelve 120 BBL batches of Scarlet Letter Seltzer to 3.0 vol/vol while meeting all beverage quality and safety requirements. The Carbo Rock-It was able to reduce carbonation …