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Full-Text Articles in Life Sciences

To Laugh Or Not To Laugh: That Is The Question Of Humor Techniques And Sex Differences, Yu-Chen Chan Jan 2023

To Laugh Or Not To Laugh: That Is The Question Of Humor Techniques And Sex Differences, Yu-Chen Chan

Journal of Educational Technology Development and Exchange (JETDE)

A humor structure comprises two essential stages: the setup and the punch line. The punch line stage is to provide the incongruity resolution that creates amusement in humor. The current article aimed to look into how humor is amusing and how it differs between the sexes. Functional and effective connectivity analyses in cognitive and affective neuroscience have facilitated the implications of humor comprehension, appreciation, and laughter responses. The processing of incongruity-resolution humor revealed effective connectivity from the amygdala to the precuneus (amygdala → precuneus). Conversely, the processing of nonsense humor demonstrated effective connectivity from the amygdala to the inferior frontal …


Expression And Purification Of The Bacterial Protein Curli Csga And Its Cross-Interactions With Amyloid-B, Leah Grace Cantrell Jun 2022

Expression And Purification Of The Bacterial Protein Curli Csga And Its Cross-Interactions With Amyloid-B, Leah Grace Cantrell

Honors Theses

One of the main causes of neurodegenerative diseases is aggregation of amyloid proteins that are toxic to the neurons. Proteins like amyloid-β (Aβ) and α-syneuclein (α-syn) form hallmark aggregate lesions that contribute to pathological processes in the brain in Alzheimer and Parkinson’s patients, respectively. Recent ground-breaking studies have suggested a link between the microbiota of the gut and neurodegenerative diseases, called the “gut-brain axis.” It has been long known that the protein, CsgA found in many enteric bacteria, forms amyloid fibers of its own called Curli. Curli fibrils are a structural component of bacterial colonies and maintain the integrity of …


The Ethical Justification Of Equal Candidacy For Organ Transplantation In Alcoholic Patients, Peter A. Depergola Ii May 2018

The Ethical Justification Of Equal Candidacy For Organ Transplantation In Alcoholic Patients, Peter A. Depergola Ii

Journal of Health Ethics

An increasingly blurred understanding of the distinctive challenges posed to transplantation medicine and, by extension, public health, by the debilitating reality of alcoholism suggests a critical need to revisit the relationship between causality, candidacy, and culpability in light of substance addiction. This essay grounds its arguments in two, straightforward premises: (i) compassionate medical practice - understood as the sympathetic willingness to enter into the existential suffering of another in order to ameliorate the anguish invoked by disease - rests on the fiduciary relationship shared between provider and patient; and (ii) allocating medical goods according to moral desert rather than existential …