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Cell and Developmental Biology

Selected Works

1987

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

The Lin-14 Locus Of Caenorhabditis Elegans Controls The Time Of Expression Of Specific Postembryonic Developmental Events, Victor R. Ambros, H. Robert Horvitz May 1987

The Lin-14 Locus Of Caenorhabditis Elegans Controls The Time Of Expression Of Specific Postembryonic Developmental Events, Victor R. Ambros, H. Robert Horvitz

Victor R. Ambros

The lin-14 locus of Caenorhabditis elegans plays an important role in specifying the normal timing and sequence of developmental events in the lateral hypodermal cell lineages. The results of gene dosage, complementation, and temperature-shift experiments indicate that the fates expressed by cells at successive stages of these cell lineages are specified by the level of lin-14 activity and that lin-14 acts at multiple times during development to control stage-specific choices of cell fate. Our observations suggest that during normal development a reduction in the level of lin-14 gene function causes the sequential expression of stage-specific cell fates.

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Mcnamara 1987 Uiuc Phd Dissertation - Morphogenetic Movements Contributing To Cell Aggregation In Dictyostelium Discoideum Wild-Type And Streamer F Mutants, George Mcnamara Apr 1987

Mcnamara 1987 Uiuc Phd Dissertation - Morphogenetic Movements Contributing To Cell Aggregation In Dictyostelium Discoideum Wild-Type And Streamer F Mutants, George Mcnamara

George McNamara

McNamara 1987 UIUC PhD Dissertation - Morphogenetic movements contributing to cell aggregation in Dictyostelium discoideum wild-type and streamer F mutants.
PhD Supervisor: Robert P. Futrelle.
We investigated some cell processes which may contribute to cell aggregation patterns in the social ameba Dictyostelium discoideum. Aggregation is known to be mediated by chemotaxis up periodic extracellular cAMP gradients; however, the details of cell movement during this stage of development have not been reported. We recorded cell behavior by time-lapse cinemicroscopy and collected cell motion and cell shape data by computer-aided planimetry.
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Bottom line is that I discovered that the reason streamerF …

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