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Insulin Treatment Increases Myocardial Ceramide Accumulation And Disrupts Cardiometabolic Function, Aimee Elizabeth Hodson
Insulin Treatment Increases Myocardial Ceramide Accumulation And Disrupts Cardiometabolic Function, Aimee Elizabeth Hodson
Theses and Dissertations
Prevalence of diabetes, especially type 2 diabetes mellitus (T2DM) is increasing worldwide. Millions of people are already affected by T2DM and estimates predict over half a billion people will likely be suffering from the disease by 2030. T2DM is associated with an increased risk of developing cardiovascular disease. Cardiovascular dysfunction is the leading cause of mortality among type 2 diabetics. Treatment for T2DM has changed over time. Though it was once known as insulin independent, a large portion of type 2 diabetics are now treated with insulin injections. However, type 2 diabetics treated with insulin are more likely to suffer …