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Full-Text Articles in Life Sciences
Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson
Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson
Graduate Theses and Dissertations
Context: Cardiovascular disease (CVD) is one of the leading causes of mortality in the United States, accounting for about 1 in every 4 deaths annually. Studies have shown that passive heating does have some degree of effect on arterial stiffness, but not much is known about populations with higher stiffness. Objective: To examine the independent effect of core temperature increase during passive heating on arterial stiffness. Methods: Participants visited the lab three times; one familiarization and two experimental trials. The experimental trials consisted of subjects being passively heated in an environment of 40°C / 40% relative humidity (HEAT) or normal …
Impacts Of Micrornas On Skeletal Muscle Protein Synthesis And Mitochondrial Quality, David Lee
Impacts Of Micrornas On Skeletal Muscle Protein Synthesis And Mitochondrial Quality, David Lee
Graduate Theses and Dissertations
microRNA (miRNA) post-transcriptional modification is becoming a well-established mechanism for controlling mRNA translation. microRNAs -1, -133, and -206 are under the control of skeletal muscle promoters and affect muscle plasticity and metabolic health. A detailed review on the generation and processing of miRNAs with a view to skeletal muscle brings up intriguing connections in the transcriptional connections between multiple miRNAs. Additionally, exciting new research has defined a role of miRNAs in skeletal muscle mitochondria showing an additional, direct link to metabolic function. Multiple investigations in models of exercise, aging, hypertrophy, and injury have shown how these interventions can affect miRNA …
The Effects Of Apoe Knock Out On Skeletal Muscle Regeneration: A Look Into Markers Of Protein Synthesis And Satellite Cell Function, Joshua Eden Ragland
The Effects Of Apoe Knock Out On Skeletal Muscle Regeneration: A Look Into Markers Of Protein Synthesis And Satellite Cell Function, Joshua Eden Ragland
Graduate Theses and Dissertations
ApoE helps regulate serum cholesterol levels by adding in transport of cholesterol into the cells, as well as, to the liver. ApoE knockout mice (ApoE KO) present a model that demonstrates the effects of hypercholesterolemia. Damage to muscle stimulates a complex regenerative response. The effects of high cholesterol on this regenerative response are not known. PURPOSE: To determine if skeletal muscle regeneration is altered in apoE KO mice by measuring protein synthesis regulator IGF-1, Akt, mTOR, and p70S6K, cell cycle regulator cyclin D1, and myogenic regulatory factors myoD and myogenin. METHODS: Female C57/BL6 (WT) and apoE KO were assigned to …
Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers
Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers
Graduate Theses and Dissertations
Long-term exposure to head-supported mass (HSM) has been linked with spinal degeneration including foraminal stenosis and disc deterioration. Anecdotally, HSM has also been linked to neck and arm pain and muscle atrophy, but nerve function has not been tested specifically. The combined effect of various head positions and HSM may be sufficient to compress the nerve root in aviators and Soldiers during job performance, potentially leading to short- and long-term neuromuscular effects. The Hoffmann (H) reflex, a well-established measure of nerve function, has shown to be sensitive to changes in nerve root space which occurs with different head positions. This …
The Use Of Cortisol And Hba1c As Biomarkers Of Stress In University Administrators, Jacilyn Marie Olson
The Use Of Cortisol And Hba1c As Biomarkers Of Stress In University Administrators, Jacilyn Marie Olson
Graduate Theses and Dissertations
PURPOSE: The purpose of this study was to explore the impact of perceived stress and cardiorespiratory fitness on cortisol and HbA1c, biomarkers of stress, in a group of select university administrators. The impact of gender on these relationships was of special concern. METHODS: University administrators with job titles of Chancellor, Provost, Vice Chancellors and Vice Provosts of the university, and Deans and Associate Deans at the college level were recruited. Twenty-five administrators (15 males and 10 females) agreed to participate and completed a battery of assessments that included completion of the University Administrative Concerns Questionnaire, a finger-stick blood test for …