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Immunological Effects Of Ketoconazole, Itraconazole And Fluconazole On Lymphocyte Cell Proliferation And Natural Killer Cell Activity In Immune-Normal, Cyclosporine-Compromised And Cyclophosphamide-Compromised Mouse Models, Jeffrey Tullis Mitchell
Immunological Effects Of Ketoconazole, Itraconazole And Fluconazole On Lymphocyte Cell Proliferation And Natural Killer Cell Activity In Immune-Normal, Cyclosporine-Compromised And Cyclophosphamide-Compromised Mouse Models, Jeffrey Tullis Mitchell
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Over the past several years there has been a steady increase in the incidence of immunologically compromised patients. This has been the result of both chemical agents, such as those used in cancer chemotherapy, and biological agents such as HIV, the cause of Acquired lmmunodefeciency Syndrome (AIDS). The increase in immune-suppressed patients has lead to an increase in life-threatening mycoses requiring treatment with antifungal agents. Pharmaceutical companies have increased research for the development of new antifungal agents which are more effective and less toxic than those that are currently used. Several researchers have reported on antifungal agents that demonstrate both …