Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 16 of 16

Full-Text Articles in Life Sciences

Modulation Of The Host Response To Tacaribe Arenavirus Infection In Ag129 Mice By My-24, Eric Sefing Dec 2012

Modulation Of The Host Response To Tacaribe Arenavirus Infection In Ag129 Mice By My-24, Eric Sefing

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

MY-24 is a new antiviral compound recently shown to protect immunocompromised mice from lethal challenge with Tacaribe virus (TCRV). Tacaribe virus is incapable of causing disease to humans, but is closely related to the highly pathogenic New World arenaviruses that cause often-fatal viral hemorrhagic fever syndromes. Remarkably, MY-24 prevents mortality without reducing virus burden in the circulation or tissues. To investigate the mechanism by which MY-24 protects AG129 mice against Tacaribe virus infection, we first characterized the natural history of disease in the model with an emphasis on host immune response and blood vessel function to establish the best times …


Clark's Nutcracker Seed Harvest Patterns In Glacier National Park And A Novel Method For Monitoring Whitebark Pine Cones, Monika E. Maier May 2012

Clark's Nutcracker Seed Harvest Patterns In Glacier National Park And A Novel Method For Monitoring Whitebark Pine Cones, Monika E. Maier

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Clark's Nutcracker (Nucifraga columbiana) is the primary seed disperser of whitebark pine (Pinus albicaulis), which is in decline throughout its range. There is concern that a decline in whitebark pine will lead to a subsequent decline in local populations of Clark's Nutcracker. Because natural regeneration depends on the presence of Clark's Nutcracker, the process of harvesting whitebark pine seeds needs to be fully understood. In addition, resource managers need a cost-effective method for monitoring nutcracker occurrence in whitebark pine stands during the seed harvest season. I visited eleven study sites in Glacier National Park, Montana, where …


Caddisfly Larvae (Limnephilidae) As Predators Of Newt (Taricha Granulosa) Eggs: Another Player In The Coevolutionary Arms Race Revolving Around Tetrodotoxin?, Brian G. Gall May 2012

Caddisfly Larvae (Limnephilidae) As Predators Of Newt (Taricha Granulosa) Eggs: Another Player In The Coevolutionary Arms Race Revolving Around Tetrodotoxin?, Brian G. Gall

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Some populations of newts (Taricha granulosa) possess large quantities of the neurotoxin tetrodotoxin (TTX) in their skin and eggs. Many populations of garter snake (Thamnophis sirtalis) are resistant to this toxin and can consume large numbers of newts with no negative effects. Despite the wealth of information acquired on the interaction between newts and their predator, garter snakes, very little research has been conducted on possible interactions between newts and other predators. I conducted a suite of experiments examining for the presence of other predators on newts, specifically focusing on predators of their eggs and larvae. …


Characterization Of The Function And Interaction Of Proteins Involved In Exopolysaccharide Synthesis In Streptococcus Thermophilus, Streptococcus Iniae, And Lactococcus Lactis Subsp. Cremoris, Angela D. Cefalo May 2012

Characterization Of The Function And Interaction Of Proteins Involved In Exopolysaccharide Synthesis In Streptococcus Thermophilus, Streptococcus Iniae, And Lactococcus Lactis Subsp. Cremoris, Angela D. Cefalo

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Many microorganisms produce capsules of repeating sugar units that surround the cell called exopolysaccharides. The synthesis of these capsules is a complex process that involves numerous protein components. A better understanding of the way these proteins function and interact with one another will benefit many industrial processes by aiding in the construction of bacterial strains with enhanced properties and could also lead to new treatment strategies against microbial pathogens in which capsule production is important in their ability to cause disease. In this study, the function of one of the proteins involved in the regulation of capsule synthesis in the …


Social Organization And Decision Making In North American Bison: Implications For Management, Ryan A. Shaw May 2012

Social Organization And Decision Making In North American Bison: Implications For Management, Ryan A. Shaw

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Social organization varies widely among herbivores, and the level of social organization in bison is widely debated. I hypothesized that when mother-daughter relationships are allowed to develop, bison form long-term associations. In my study, 25 treatment mothers were selected from a free-ranging herd and kept together with their calves, while 25 control females had their calves forcefully removed. Treatment mothers and offspring had by far the greatest number of associations with a greater percentage of individuals with a half weight index (HWI) > 0.50. The strongest associations (HWI > 0.31) were among treatment mothers and their offspring. Moreover, these associations persisted over …


Two New Species Of Trigonotylus (Hemiptera: Heteroptera: Miridae: Stenodemini) From Western Canada And Northwestern United States, G G.E. Scudder, Michael D. Schwartz Jan 2012

Two New Species Of Trigonotylus (Hemiptera: Heteroptera: Miridae: Stenodemini) From Western Canada And Northwestern United States, G G.E. Scudder, Michael D. Schwartz

Green Canyon Environmental Research Area, Logan Utah

No abstract provided.


Livestock Foraging Behavior In Response To Sequence And Interactions Among Alkaloids, Tannins, And Saponins, Tiffany L. Jensen Jan 2012

Livestock Foraging Behavior In Response To Sequence And Interactions Among Alkaloids, Tannins, And Saponins, Tiffany L. Jensen

Green Canyon Environmental Research Area, Logan Utah

No abstract provided.


The Role Of Fine-Scale Habitat Associations In Structuring Spider Assemblages: Determinants Of Spatial Patterns In Community Compostion, Stephanie M. Cobbold Jan 2012

The Role Of Fine-Scale Habitat Associations In Structuring Spider Assemblages: Determinants Of Spatial Patterns In Community Compostion, Stephanie M. Cobbold

Green Canyon Environmental Research Area, Logan Utah

No abstract provided.


Survey Of Erwinia Amylovora, Causal Agent Of Fire Blight, From Apple And Pear Orchards In Utah For Streptomycin Resistance, Christine Dhiman Jan 2012

Survey Of Erwinia Amylovora, Causal Agent Of Fire Blight, From Apple And Pear Orchards In Utah For Streptomycin Resistance, Christine Dhiman

Browse All Undergraduate research

Fire blight caused by the bacterium Erwinia amylovora results in millions of dollar in losses worldwide. It is the most important disease problem for apple and pear growers in Utah. Currently the only effective management strategy is application of the antibiotic streptomycin. In 2006, resistant isolates were detected in an apple orchard in Utah County. To determine the distribution of resistant isolates, samples collected in 2006, 2007, 2010 and 2011 from orchards across Utah were tested for resistance to streptomycin. Isolates were screened at 0, 100 and 1000ppm of streptomycin. Bacteria were spread on LB agar. A hole was punched …


Survey Of Erwinia Amylovora, Causal Agent Of Fire Blight, From Apple And Pear Orchards In Utah For Streptomycin Resistance, Christine Dhiman Jan 2012

Survey Of Erwinia Amylovora, Causal Agent Of Fire Blight, From Apple And Pear Orchards In Utah For Streptomycin Resistance, Christine Dhiman

NCUR

Fire blight caused by the bacterium Erwinia amylovora results in millions of dollar in losses worldwide. It is the most important disease problem for apple and pear growers in Utah. Currently the only effective management strategy is application of the antibiotic streptomycin. In 2006, resistant isolates were detected in an apple orchard in Utah County. To determine the distribution of resistant isolates, samples collected in 2006, 2007, 2010 and 2011 from orchards across Utah were tested for resistance to streptomycin. Isolates were screened at 0, 100 and 1000ppm of streptomycin. Bacteria were spread on LB agar. A hole was punched …


Strong Self-Limitation Promotes The Persistence Ofrare Species, G. M. Yenni, P. B. Adler, S.K. Morgan Ernest Jan 2012

Strong Self-Limitation Promotes The Persistence Ofrare Species, G. M. Yenni, P. B. Adler, S.K. Morgan Ernest

Biology Faculty Publications

Theory has recognized a combination of niche and neutral processes each contributing, with varying importance, to species coexistence. However, long-term persistence of rare species has been difficult to produce in trait-based models of coexistence that incorporate stochastic dynamics, raising questions about how rare species persist despite such variability. Following recent evidence that rare species may experience significantly different population dynamics than dominant species, we use a plant community model to simulate the effect of disproportionately strong negative frequency dependence on the long-term persistence of the rare species in a simulated community. This strong self-limitation produces long persistence times for the …


Improved Ex Vivo Method For Microbiocidal Activity Across Vertebrate Species, Susannah S. French, Lorin A. Neuman-Lee Jan 2012

Improved Ex Vivo Method For Microbiocidal Activity Across Vertebrate Species, Susannah S. French, Lorin A. Neuman-Lee

Biology Faculty Publications

The field of ecoimmunology is currently undergoing rapid expansion, whereby biologists from a wide range of ecological disciplines are increasingly interested in assessing immunocompetence in their study organisms. One of the key challenges to researchers is determining what eco-immune measures to use in a given experiment. Moreover, there are limitations depending on study species, requirements for specific antibodies, and relevance of the methodology to the study organism. Here we introduce an improved ex vivo method for microbiocidal activity across vertebrate species. The utility of this assay is that it determines the ability of an organism to remove a pathogen that …


An Improved Competitive Inhibition Enzymatic Immunoassay Method For Tetrodotoxin Quantification, James P. Strange, Becky L. Williams, Susannah S. French Jan 2012

An Improved Competitive Inhibition Enzymatic Immunoassay Method For Tetrodotoxin Quantification, James P. Strange, Becky L. Williams, Susannah S. French

Biology Faculty Publications

Quantifying tetrodotoxin (TTX) has been a challenge in both ecological and medical research due to the cost, time and training required of most quantification techniques. Here we present a modified Competitive Inhibition Enzymatic Immunoassay for the quantification of TTX, and to aid researchers in the optimization of this technique for widespread use with a high degree of accuracy and repeatability.


Methodological Tools, Ethan P. White, Xiao Xiao, J. B. Nick, Richard M. Sibly Jan 2012

Methodological Tools, Ethan P. White, Xiao Xiao, J. B. Nick, Richard M. Sibly

Biology Faculty Publications

Methodological approaches for comparing metabolic theory predictions to empirical data fall into two general categories: 1) determining if the general functional form of a relationship predicted by the theory is valid; and 2) determining whether the observed values of the parameters match the specific quantitative predictions made by the theory. Both of these categories of analysis rely on being able to accurately determine the best fitting form of a model with the same general functional form as that of MTE, so we will begin by discussing how this has typically been done using OLS regression on appropriately transformed data. Potential …


Investigating Human Impact In The Environment With Faded Scaffolded Inquiry Supported By Technologies, D. T. Longhurst, M. Longhurst, A. M. Duffy, Paul G. Wolf Jan 2012

Investigating Human Impact In The Environment With Faded Scaffolded Inquiry Supported By Technologies, D. T. Longhurst, M. Longhurst, A. M. Duffy, Paul G. Wolf

Biology Faculty Publications

Teaching science as inquiry is advocated in all national science education documents and by leading science and science teaching organizations. In addition to teaching science as inquiry, we recognize that learning experiences need to connect to students’ lives. This article details how we use a sequence of faded scaffolded inquiry supported by technologies to engage students meaningfully in science connected to their lives and schoolyards. In this approach, more teacher guidance is provided earlier in the inquiry experiences before this is faded later in the sequence, as students are better prepared to complete successful inquiries. The sequence of inquiry experiences …


Widespread Triploidy In Western North American Aspen (Populus Tremuloides), Karen E. Mock, Colin M. Callahan, M. Nurul Islam-Faridi, John D. Shaw, Hardeep S. Rai, Stewart C. Sanderson, Carol A. Rowe, Ronald J. Rye, Michael D. Madritch, Richard S. Gardner, Paul G. Wolf Jan 2012

Widespread Triploidy In Western North American Aspen (Populus Tremuloides), Karen E. Mock, Colin M. Callahan, M. Nurul Islam-Faridi, John D. Shaw, Hardeep S. Rai, Stewart C. Sanderson, Carol A. Rowe, Ronald J. Rye, Michael D. Madritch, Richard S. Gardner, Paul G. Wolf

Biology Faculty Publications

We document high rates of triploidy in aspen (Populus tremuloides) across the western USA (up to 69% of genets), and ask whether the incidence of triploidy across the species range corresponds with latitude, glacial history (as has been documented in other species), climate, or regional variance in clone size. Using a combination of microsatellite genotyping, flow cytometry, and cytology, we demonstrate that triploidy is highest in unglaciated, drought-prone regions of North America, where the largest clone sizes have been reported for this species. While we cannot completely rule out a low incidence of undetected aneuploidy, tetraploidy or duplicated loci, our …