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Biology

Duquesne University

Electronic Theses and Dissertations

Acetylcholinesterase inhibitor

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Evaluating The Biological Effects And Safety Of Exposure To Low, Putatively Safe Concentrations Of The Common Pesticide Chlorpyrifos Using An Anuran Model, Sara Mcclelland Aug 2020

Evaluating The Biological Effects And Safety Of Exposure To Low, Putatively Safe Concentrations Of The Common Pesticide Chlorpyrifos Using An Anuran Model, Sara Mcclelland

Electronic Theses and Dissertations

In the US, over 1.1 billion pounds of pesticides are applied annually. Unfortunately, pesticides contaminate natural habitats affecting animal health. Chlorpyrifos (CPF) is an organophosphorous insecticide that contaminates surface waters. Few studies have assessed the impacts of CPF at low, ecologically realistic doses. I aimed to test the effects of low dose CPF exposures on biological parameters including body morphology, hormone levels, and brain development in Northern Leopard Frogs (Lithobates pipiens), a common vertebrate model. To determine if CPF exposure has direct impacts or indirectly impacts animals through the disruption of the food web, I examined CPF exposure …