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Increased Reactive Oxygen Intermediate Production By Hemocytes Withdrawn From Crassostrea Virginica Infected With Perkinsus Marinus, Rs Anderson, Ky Paynter, Em Burreson

VIMS Articles

Perkinsus marinus is a protozoan parasite responsible for a major infectious disease of the Eastern oyster, Crassostrea virginica. Nonspecific immunity was assayed in oysters with known intensities of infection so that the physiological responses of the host elicited by the parasite could be better understood. This report describes the capacity of hemocytes to generate reactive oxygen intermediates during the progression of the disease. The hemocytes constitute the major internal defense effector system of oysters, and cytotoxic oxygen species are thought to play central roles in antimicrobial activities of hemocytes and other phagocytic cells. Production of oxyradicals by both resting and …