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Full-Text Articles in Life Sciences
Synthesis, Evaluation, And Characterization Of An Ergotamine Imprinted Styrene-Based Polymer For Potential Use As An Ergot Alkaloid Selective Adsorbent, Manoj B. Kudupoje, Eric S. Vanzant, Kyle R. Mcleod, Alexandros Yiannikouris
Synthesis, Evaluation, And Characterization Of An Ergotamine Imprinted Styrene-Based Polymer For Potential Use As An Ergot Alkaloid Selective Adsorbent, Manoj B. Kudupoje, Eric S. Vanzant, Kyle R. Mcleod, Alexandros Yiannikouris
Animal and Food Sciences Faculty Publications
Alkaloid toxicities negatively impact livestock health and production. To assess alkaloid occurrences, adsorbent technologies may offer effective means to their extraction and isolation from a complex feed matrix. In this study, molecularly imprinted polymers (MIPs) were synthesized and evaluated for their specificity of binding to various ergot alkaloids. Co-polymers of styrene and hydroxyethyl methacrylate were synthesized in the absence or presence of an ergotamine (ETA) template, yielding non-imprinted polymer (NIP) and molecularly imprinted polymer (MIP), respectively. The influence of parameters such as pH, temperature, and initial concentration on the adsorption of ergot alkaloids was evaluated along with their application as …