Life Sciences Commons^™

Identifying Genome Associations With Unique Mastitis Phenotypes In Response To Intramammary Streptococcus Uberis Challenge, Lydia Jean Siebert

Doctoral Dissertations

Mastitis, the inflammation of the mammary gland, dramatically decreases dairy industry revenues and milk quality, making improved control and prevention methods a goal of the industry. Prior research has observed variation in response to experimental challenge with regards to inflammation indicators, S. uberis concentrations, and the need for antibiotics. To determine possible causes of the observed variation following experimental S. uberis intramammary challenge, we performed genome association analyses (N = 34 – 36 Holstein dairy cows), a linkage analysis, and S. uberis milk inoculation (N = 21 Holstein dairy cows) trials. Association analyses were done using Illumina’s BovineSNP50 BeadChip and …