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Articles 1 - 4 of 4
Full-Text Articles in Life Sciences
Harness Organoid Models For Virological Studies In Animals: A Cross-Species Perspective, Yongming Sang, Laura C. Miller, Rahul K. Nelli, Luis Gabriel Giménez-Lirola
Harness Organoid Models For Virological Studies In Animals: A Cross-Species Perspective, Yongming Sang, Laura C. Miller, Rahul K. Nelli, Luis Gabriel Giménez-Lirola
Agricultural and Environmental Sciences Faculty Research
Animal models and cell culture in vitro are primarily used in virus and antiviral immune research. Whereas the limitation of these models to recapitulate the viral pathogenesis in humans has been made well aware, it is imperative to introduce more efficient systems to validate emerging viruses in both domestic and wild animals. Organoids ascribe to representative miniatures of organs (i.e., mini-organs), which are derived from three-dimensional culture of stem cells under respective differential conditions mimicking endogenous organogenetic niches. Organoids have broadened virological studies in the human context, particularly in recent uses for COVID19 research. This review examines the status and …
Effects Of Lactobacillus Reuteri And Streptomyces Coelicolor On Growth Performance Of Broiler Chickens, Sarayu Bhogoju, Collins N. Khwatenge, Thyneice Taylor-Bowden, Gabriel Oluwamuyiwa Akerele, Boniface M. Kimathi, Joseph Donkor, Samuel N. Nahashon
Effects Of Lactobacillus Reuteri And Streptomyces Coelicolor On Growth Performance Of Broiler Chickens, Sarayu Bhogoju, Collins N. Khwatenge, Thyneice Taylor-Bowden, Gabriel Oluwamuyiwa Akerele, Boniface M. Kimathi, Joseph Donkor, Samuel N. Nahashon
Agricultural and Environmental Sciences Faculty Research
There are well documented complications associated with the continuous use of antibiotics in the poultry industry. Over the past few decades, probiotics have emerged as viable alternatives to antibiotics; however, most of these candidate probiotic microorganisms have not been fully evaluated for their effectiveness as potential probiotics for poultry. Recent evaluation of a metagenome of broiler chickens in our laboratory revealed a prevalence of Lactobacillus reuteri (L. reuteri) and Actinobacteria class of bacteria in their gastrointestinal tract. In this study Lactobacillus reuteri and Streptomyces coelicolor (S. coelicolor) were selected as probiotic bacteria, encapsulated, and added into broiler feed at a …
Recent Advances In The Application Of Crispr/Cas9 Gene Editing System In Poultry Species, Collins N. Khwatenge, Samuel N. Nahashon
Recent Advances In The Application Of Crispr/Cas9 Gene Editing System In Poultry Species, Collins N. Khwatenge, Samuel N. Nahashon
Agricultural and Environmental Sciences Faculty Research
CRISPR/Cas9 system genome editing is revolutionizing genetics research in a wide spectrum of animal models in the genetic era. Among these animals, is the poultry species. CRISPR technology is the newest and most advanced gene-editing tool that allows researchers to modify and alter gene functions for transcriptional regulation, gene targeting, epigenetic modification, gene therapy, and drug delivery in the animal genome. The applicability of the CRISPR/Cas9 system in gene editing and modification of genomes in the avian species is still emerging. Up to date, substantial progress in using CRISPR/Cas9 technology has been made in only two poultry species (chicken and …
Sensitivity Of Wild-Type And Rifampicin-Resistant O157 And Non-O157 Shiga Toxin-Producing Escherichia Coli To Elevated Hydrostatic Pressure And Lactic Acid In Ground Meat And Meat Homogenate, Abimbola Allison, Aliyar Cyrus Fouladkhah
Sensitivity Of Wild-Type And Rifampicin-Resistant O157 And Non-O157 Shiga Toxin-Producing Escherichia Coli To Elevated Hydrostatic Pressure And Lactic Acid In Ground Meat And Meat Homogenate, Abimbola Allison, Aliyar Cyrus Fouladkhah
Agricultural and Environmental Sciences Faculty Research
Various serogroups of Shiga toxin-producing Escherichia coli have been epidemiologically associated with foodborne disease episodes in the United States and around the globe, with E. coli O157: H7 as the dominant serogroup of public health concern. Serogroups other than O157 are currently associated with about 60% of Shiga toxin-producing E. coli related foodborne illness episodes. Current study evaluated sensitivity of the O157 and epidemiologically important non-O157 serogroups of the pathogen to elevated hydrostatic pressure and 1% lactic acid. Pressure intensity of 250 to 650 MPa were applied for 0 to 7 min for inactivation of strain mixtures of …