Life Sciences Commons^™

Altered Gene Response To Aflatoxin B1 In The Spleens Of Susceptible And Resistant Turkeys, Kent M. Reed, Kristelle M. Mendoza, Roger A. Coulombe Jr.

Animal, Dairy, and Veterinary Science Faculty Publications

Susceptibility and/or resistance to aflatoxin B₁ (AFB₁) is a threshold trait governed principally by glutathione S transferase (GST)-mediated detoxification. In poultry, domesticated turkeys are highly sensitive to AFB₁, most likely due to dysfunction in hepatic GSTs. In contrast, wild turkeys are comparatively resistant to aflatoxicosis due to the presence of functional hepatic GSTAs and other possible physiological and immunological interactions. The underlying genetic basis for the disparate GST function in turkeys is unknown as are the broader molecular interactions that control the systemic response. This study quantifies the effects of dietary AFB₁ on gene …

Differential Transcriptome Responses To Aflatoxin B1 In The Cecal Tonsil Of Susceptible And Resistant Turkeys, Kent M. Reed, Kristelle M. Mendoza, Roger A. Coulombe Jr.

Animal, Dairy, and Veterinary Science Faculty Publications

The nearly-ubiquitous food and feed-borne mycotoxin aflatoxin B₁ (AFB₁) is carcinogenic and mutagenic, posing a food safety threat to humans and animals. One of the most susceptible animal species known and thus a good model for characterizing toxicological pathways, is the domesticated turkey (DT), a condition likely due, at least in part, to deficient hepatic AFB₁-detoxifying alpha-class glutathione S-transferases (GSTAs). Conversely, wild turkeys (Eastern wild, EW) are relatively resistant to the hepatotoxic, hepatocarcinogenic and immunosuppressive effects of AFB₁ owing to functional gene expression and presence of functional hepatic GSTAs. This study was designed to …

Bulletin No. 102 - Poultry Experiments, James Dryden

UAES Bulletins

There are many problems connected with the housing of poultry. Among them the question of egg fertility is one of the most important. We have begun investigations at this Station to learn if possible what kind or method of housing is most conducive to a high percentage of fertility in the eggs. It is a serious question with many poultrymen how to maintain the percentage of fertile eggs, and there have been cases where the poultryman has been driven out of the business because of inability to renew his flock. There is little doubt that the artificial methods, both in …

Bulletin No. 92 - Poultry Experiments, James Dryden

UAES Bulletins

This bulletin reports experiments extending over several

years on the following subjects:

1. The egg-type in hens.

2. Breeding to increase egg yield.

3. Cost and profit of egg production.

4. Weight and cost of food eaten.

5. The value of exercise for the laying hen.

6. The relative value of different breeds.

7. The most profitable age of the hen.

8. The relative value of different forms of animal food.

9. The value of fat in poultry foods.

10. Feeding color into the egg.

11. Incubator experiments.

12. Tests of evaporation of eggs during incubation.

13. Tests of carbonic …

Bulletin No. 67 - Poultry Experiments, James Dryden

UAES Bulletins

The results of the third year's work in egg production at this Station, together with the summing up of the results of the three years, are given herewith. The third year's work began Nov. 7,1898, and ended Nov. 1,1899. Some of the experiments originally planned have run the full period of three years. In addition to a continuation of the original work a set of feeding experiments was conducted during the third year. This latter work was made possible by the erection of an addition to the poultry house which doubled the experimental capacity of the building and made possible …

Bulletin No. 60 - Poultry Experiments, James Dryden

UAES Bulletins

The experiments in egg production outlined in Bulletin No. 51 of this Station, were, in the main, continued during the year ending November 7, 1898. The results of this second year's work are reported herein.

Bulletin No. 51 - Poultry Experiments, James Dryden

UAES Bulletins

In November, 1896, experiments in egg production were begun at this station.