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Rapid Quantitative Analysis Of Toxic Norditerpenoid Alkaloids In Larkspur (Delphinium Spp.) By Flow Injection - Electrospray Ionization – Mass Spectrometry, Dale R. Gardner, Stephen T. Lee, Daniel Cook
Rapid Quantitative Analysis Of Toxic Norditerpenoid Alkaloids In Larkspur (Delphinium Spp.) By Flow Injection - Electrospray Ionization – Mass Spectrometry, Dale R. Gardner, Stephen T. Lee, Daniel Cook
Poisonous Plant Research (PPR)
A rapid flow injection - electrospray ionization – mass spectrometry (FI-ESI-MS) method for the quantitative and qualitative analysis of norditerpenoid alkaloids in larkspur plants was developed. The FI-ESI-MS method was calibrated for alkaloid concentrations with larkspur plant samples against an existing Fourier transform infrared spectroscopy FTIR method. There was a strong correlation (r = 0.9926, r = 0.9891) between the FTIR and FI-ESI-MS methods. The relative standard deviation (RSD) for all measurements were ≤ 6.2 % except for the sample with the lowest concentration which was 19%. The sample throughput of the FI-ESI-MS method is much higher than the FTIR …
An Evaluation Of The Susceptibility Of Goats To Larkspur Toxicosis, Kevin D. Welch, Clint A. Stonecipher, Dale R. Gardner, Benidict T. Green, Daniel Cook
An Evaluation Of The Susceptibility Of Goats To Larkspur Toxicosis, Kevin D. Welch, Clint A. Stonecipher, Dale R. Gardner, Benidict T. Green, Daniel Cook
Poisonous Plant Research (PPR)
Larkspurs (Delphinium spp.) are a major cause of cattle losses in western North America, whereas sheep have been shown to be resistant to larkspur toxicosis. Goats are often used as a small ruminant model to study poisonous plants, even though they can be more resistant to some poisonous plants. It is not known how susceptible goats are to the adverse effects of larkspurs. In this study, we evaluated the susceptibility of goats to larkspur toxicosis by performing a dose-response study. We dosed goats with D. barbeyi collected near Cedar City, Utah at 3.3, 4.4, 6.6, 8.8 and 10.0 g …